Safety and efficacy of microvascular decompression in elderly patients with cranial neuropathy / 中华老年医学杂志

Objective To investigate the safety and clinical efficacies of microvascular decompression(MVD) on cranial neuropathy such as trigeminal neuralgia (TN),hemifacial spasm (HFS)and glossopharyngeal neuralgia(GN)in elderly patients.Methods Clinical data of 72 patients aged 70 years and over diagnosed as cranial neuropathy and undergoing microvascular decompression in our department from January 2015 to August 2017 were retrospectively analyzed.The curative effect and complications were analyzed after treatment.Results All patients successfully underwent MVD under general anesthesia.The facial pain completely disappeared or was significantly improved in 85.7 ％ (30/35)of TN patients one year after operation.The intermittent tonic contractions of the facial muscles were completely disappeared in 94.3％ (33/35)of HFS patients.Clinical symptoms were completely disappeared in 2 patients with GN,4 patients with TN and HFS and 1 patients with TN and GN.Conclusions The surgery goes well and the patients have good postoperative recovery,with no severe complications such as intracranial hematoma,infarction,cerebrospinal fluid leakage,acute hydrocephalus and death.After an adequate preoperative evaluation,MVD is safe and effective with a few complications.It can significantly improve the quality of life in elderly patients with trigeminal neuralgia,hemifacial spasm,and glossopharyngeal neuralgia.

Clinical application of post mastoid transverse incision in keyhole microvascular decompression / 中华神经医学杂志

Objective To explore the clinical value of post mastoid transverse incision in keyhole microvascular decompression (MVD) for cranial neuropathy.Methods Fifty-eight patients with trigeminal neuralgia,hemifacial spasm or glossopharyngeal neuralgia,admitted to and accepted postmastoid transverse incision keyhole surgery in our hospital from October 2015 to October 2017,were chosen.Their clinical data and efficacy were retrospectively analyzed.Results Lesions of cranial nerves in all 58 patients were exposed satisfactorily (trigeminal nerve,facial nerve,or glossopharyngeal nerve).Postoperative complications included severe facial numbness in one patient,scalp hydrops in one patient,ear discomfort in two patients,and hearing loss in two patients.No cerebrospinal fluid leakage or intracranial infection,no facial paralysis or ear deafness,no hoarseness or drinking cough,and no intracranial hemorrhage or death were observed.All patients were followed up for 3-24 months,enjoying total effective rate of 98.3％ (57/58);and no recurrence or aggravation was noted.Conclusion MVD of post mastoid transverse incision in keyhole is a safe and effective surgical method for treatment of cranial nerve disorders;the steps of craniotomy and craniotomy in this method are simple,easy accessed,and fully neurologically exposed,having high surgical safety and good postoperative cosmetic results,which is worth of promoting application.

Ramsay-Hunt Syndrome Without Vesicle Presenting With Ulilateral Abducens and Vestibular Paralysis Followed by V, VII, IX, and X Nerve Palsies

No abstract available.

Ramsay-Hunt Syndrome Without Vesicle Presenting With Ulilateral Abducens and Vestibular Paralysis Followed by V, VII, IX, and X Nerve Palsies

No abstract available.

Two Cases of Delayed Post-radiation Lower Cranial Nerve Palsies

Radiation-induced lower cranial neuropathy shows a clinical presentation similar to tumor recurrence or amyotrophic lateral sclerosis. We experienced two patients with bulbar palsies several years after radiotherapy for nasopharyngeal cancer. Brain magnetic resonance imaging showed no evidence of tumor recurrence. Electrophysiologic studies demonstrated mild denervation changes and myokymic discharges in muscles innervated by cranial nerves. Bulbar palsies progressed for 1 year then became stable. We emphasize the importance of myokymic discharges in the differential diagnosis of radiation-induced cranial neuropathy as radiation plexopathies.

Therapeutic effect of left medullary microvascular decompression on primary hypertension / 中华神经医学杂志

Objective To explore the clinical effect of left medullary microvascular decompression (MVD) on primary hypertension complicated by cerebral hematoma and cranial nerve disease. Methods After left cerebral hematomas in 26 patients and cerebellar hematomas in 2 patients were evacuated, left medullary MVD was performed via suboccipital retromastoidal approach. Fifteen of them were operated emergently. Eight hypertensive patients complicated by cranial nerve diseases (4trigeminal neuralgia, 1 glossopharyngeal neuralgia, 2 acoustic neuroma, 1 trigeminal neuroma) underwent left medullary MVD after the planned cranial nerve MVD and tumor resection. Blood pressure was monitored and the variety and dosage changes of anti-hypertension were recorded. Results Vessel loops that compressed, contacted or transfixed the medulla oblongata and vagus nerve root entry zone (REZ) were found in all patients. The offending vessel loops included posterior inferior cerebellar artery (PICA, n=20), vertebral artery (VA, n=11), and anterior inferior cerebellar artery (AICA, n=5). The relationship between the offending vessel loops and medulla oblongata, vagus nerve REZ were divided into four types: Contacting type (n=14), compressing type (n=10), adhesion type (n=9) and transfixing type (n=3). In the 36 patients, 24 hypertension cases (66.7%) were cured, 10 (27.8%) were improved, and2 (5.5%) did not get better. Conclusions Left medulla oblongata MVD is effective in treating primary hypertension. To explore and settle carefully of the drag stimulation like a string from the vessel loops deviated from the medulla, vague nerve REZ will improve the effects of medullary MVD for primary hypertension.