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1.
Rev. chil. infectol ; 34(3): 280-286, jun. 2017. ilus, tab
Article Dans Espagnol | LILACS | ID: biblio-899713

Résumé

There are very few reports of pediatric patients with infections by dematiaceous filamentous fungi. In this publication we report a case of invasive fungal infection of the nasal septum by Curvularia spicifera in a pediatric patient with acute myeloid leukemia. The patient presented with a painful scabby wound in the nasal vestibule. Culture and universal PCR were consistent with Curvularia spicifera. Early management with surgical debridement and bi-associated antifungal therapy achieved complete resolution of the lesions, with no evidence of dissemination and relapses. Clinical management of these fungal infections represents a challenge as the antifungal selection and duration of therapy is not yet well stablished.


Existen pocos reportes de infecciones por hongos dematiáceos en pediatría. Comunicamos el caso de una infección fúngica invasora del tabique nasal en un niño con una leucemia mieloide aguda, que se presentó como una lesión costrosa dolorosa en el vestíbulo nasal. Se realizó desbridamiento quirúrgico precoz y recibió tratamiento antifúngico biasociado, lográndose resolución completa de las lesiones, sin diseminación ni recaídas. El cultivo y la RPC universal fueron compatibles con Curvularia spicifera. El manejo de estas infecciones fúngicas representa un desafío, considerando que la elección del agente antifúngico y la duración de la terapia no están completamente establecidas.


Sujets)
Humains , Mâle , Enfant , Ascomycota/isolement et purification , Infections opportunistes/complications , Leucémie aigüe myéloïde/complications , Maladies du nez/complications , Phaeohyphomycose/complications , Neutropénie/complications , Infections opportunistes/microbiologie , Leucémie aigüe myéloïde/microbiologie , Maladies du nez/microbiologie , Phaeohyphomycose/microbiologie , Neutropénie/microbiologie
2.
Mycobiology ; : 210-217, 2015.
Article Dans Anglais | WPRIM | ID: wpr-729643

Résumé

A seed-borne fungus, Curvularia sp. EML-KWD01, was isolated from an indigenous wheat seed by standard blotter method. This fungus was characterized based on the morphological characteristics and molecular phylogenetic analysis. Phylogenetic status of the fungus was determined using sequences of three loci: rDNA internal transcribed spacer, large ribosomal subunit, and glyceraldehyde 3-phosphate dehydrogenase gene. Multi loci sequencing analysis revealed that this fungus was Curvularia spicifera within Curvularia group 2 of family Pleosporaceae.


Sujets)
Humains , Classification , ADN ribosomique , Champignons , Glycéraldéhyde 3-phosphate , Oxidoreductases , Grande sous-unité du ribosome , Triticum
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