Résumé
PURPOSE: Massive pediatric burns are subject to progress to wound infection and sepsis at early stage. Early escharectomy and allograft made it safer to treat the pediatric burn patients from this morbidity. The purpose of this study is to analyze the impact of the early escharectomy and temporary wound coverage with allograft on massive pediatric burns. METHODS: From January 1999 to August 2010, 55 pediatric burn patients aged 1 to 10 years whose total burn surface area was over 20% were reviewed. Among them, only 19 patients underwent escharectomy (Pediatric escharectomy group, PEG) and 36 patients underwent escharectomy and allograft (Pediatric allograft group, PAG) And 533 allograft patients (Allograft group, AG) aged over 10 whose total burn surface area were over 20% were reviewed to compare with the pediatric allograft patients. RESULTS: PAG was operated earlier (mean 3.6 days from injury) than PEG (mean 5.9 days). The mortality of PAG (8.3%) was lower than the mortality of PEG (31.6%) significantly. And the PAG were operated earlier than AG (mean 5.8 days from injury). But the difference of mortality was not significant statistically between PAG and AG. CONCLUSION: Early escharectomy and allograft is safe and effective treatment procedure for massive pediatric burn patients by preventing wound sepsis.
Sujets)
Sujet âgé , Humains , Brûlures , Sepsie , Transplantation homologue , Infection de plaieRésumé
PURPOSE: Burn wound infection, sepsis and organ failure have been major causes of death in massive burn patient. Because it is difficult to fundamentally prevent bacterial colonization by medical treatment, the need of surgical intervention is advocated by many authors. Therefore the effects of early excision and optimal time were studied. METHODS: Twenty four patients with thermal injuries, on whom early excision of eschar was performed, between June and Aug. 2003, were studied. Fascial excision over third and fourth degree burns and tangential excision over indeterminate areas were performed. Superficial and deep layers of eschar was separated and cultivated, and bacterial colony counts performed. The patients were divided into two groups: a colony count equal or greater than 10(5)/g (group A) and less than 10(5)/g (group B), and studied. The plasma endotoxin levels were assayed and compared. RESULTS: Sepsis occurred at a higher rate when the bacterial colony counts were equal or greater than 10(5)/g at the wound site. Bacterial colonization appears to be greatly increased on the 4th in of escharectomy in superficial layers, and on the 5th in deep layers, in old aged or young child patients tends to occur earlier and with greater severity. The microorganism isolated in all patients was Pseudomonas aeruginosa. There was no statistical difference in the plasma endotoxin levels between groups A and B. CONCLUSION: It is suggested that all massive burn injuries would be better treated with early excision, within 3 days after burns, especially in old aged or young child patients.