Influence of acupoint catgut embedding combined with exercise therapy on the rehabilitation effect of patients with upper limb spasticity after stroke and qi deficiency and blood stasis type / 国际中医中药杂志

Objective:To explore the influence of acupoint catgut embedding combined with exercise therapy on the rehabilitation effect of patients with upper limb spasticity after stroke and qi deficiency and blood stasis type.Methods:A total of 76 patients with qi deficiency and blood stasis type of upper limb spasticity after stroke who met the inclusion criteria in the hospital were enrolled between May 2018 and May 2020, and they were divided into two groups according to the random number table method, with 38 in each group. The control group was given conventional rehabilitation treatment, while the observation group was combined with acupoint catgut embedding and exercise therapy intervention on the basis of the control group. The degree of elbow spasm was assessed by Modified Ashworth Scale and hemiplegic hand function was evaluated by Hemiplegic Hand Function Classification Scale. Simplified Fugl-Meyer Scale was used to evaluate the limb motor ability and Modified Barthel Index was used for ability of daily living, and the adverse events during treatment were recorded.Results:After treatment, the improvement degree of elbow spasm in observation group was significantly better than that in control group ( Z=2.29, P=0.022), and the hemiplegic hand function classification was significantly better than that in control group ( Z=2.08, P=0.038). After treatment, the scores of upper and lower extremities and total score of Fugl-Meyer Scale in observation group were significantly higher than those in control group ( t=7.17, 7.40, 11.39, all Ps<0.001). While the scores of hemiplegia, faintness, shortness of breath and sallow complexion in observation group were significantly lower than those in control group ( t=7.82, 12.87, 12.55, 7.95, all Ps<0.001). The Barthel index in observation group was significantly higher than that in control group at 6 and 12 months of follow-up ( t=4.82. 6.45, all Ps<0.001). Conclusion:Acupoint catgut embedding combined with exercise therapy for intervention can improve the hemiplegic hand function, and enhance the limb motor function and daily living ability of patients with qi deficiency and blood stasis type of upper limb spasticity after stroke.

Effect of acupoint catgut embedding therapy combined with Ziwu-Liuzhu acupuncture on the sleep quality of the patients with depression / 国际中医中药杂志

Objective To investigate the effect of acupoint catgut embedding combined with Ziwu-Liuzhu theory based acupuncture on the clinical efficacy and sleep quality of depressive patients. Methods A total of 64 patients who met the inclusion criteria were randomly divided into two groups, 32 in each group. The control group was treated with routine electro-acupuncture, while the observation group was treated with acupoint catgut embedding combined with Ziwu-Liuzhu theory based acupuncture. Both groups were treated for 8 weeks. Sleep quality was assessed by Pittsburgh Sleep Quality Index (PSQI), and depression was assessed by Hamilton Depression Scale (HAMD) to evaluate the clinical efficacy. Results After treatment, the HAMD score (11.3 ± 2.4 vs. 14.5 ± 2.6, t=4.986) and PSQI index (9.6 ± 2.3 vs. 11.8 ± 2.5, t=3.307) in the observation group were significantly lower than those in the control group (P<0.01). The quality of life (12.9 ± 2.3 vs. 11.3 ± 2.5, t=2.598) and mental health score (13.5 ± 2.4 vs. 11.3 ± 2.6, t=3.413) of WHOQOL-BREF scale in the observation group were significantly higher than those in the control group (P<0.01). The total effective rate was 93.8％ (30/32) in the observation group and 75.0％ (24/32) in the control group. There were significant differences between the two groups (χ2=4.246, P=0.038). Conclusions Acupoint catgut embedding combined with Ziwu-Liuzhu theory based acupuncture can effectively improve depressive state, sleep quality and quality of life in patients with depression, and the curative effect is better than conventional electro- acupuncture treatment.

Clinical Effectiveness of Intradermal Needle-embedding Therapy for Swallowing Function in Stroke Patients with Dysphagia / 针刺研究

OBJECTIVE: To observe the clinical efficacy of intradermal needle-embedding therapy in the treatment of dysphagia in stroke patients. METHODS: A total of 80 stroke patients with dysphagia were randomly divided into treatment group and control group (n ＝ 40 in each). The control group was treated with conventional medicines, neuromuscular electrical stimulation of the bilateral midlines of the neck and swallowing function training, and the treatment group treated by intradermal needle-embedding at Lianquan (CV 23), Jialianquan-point, Yifeng (TE 17), Ashi-point, etc. (once every other day for 20 days) on the basis of the treatments used in the control group. Swallowing function (0－10 points scaling, the bigger the better)and surface electromyography (sEMG) of the bilateral suprahyoid muscles and infrahyoid muscles in the relaxing, nothing swallowing and water-swallowing conditions were tested before and after the treatment. RESULTS: After treatment, the swallowing scores were significantly increased in both groups compared with those of their individual pre-treatment (P<0.05), suggesting an improvement of swallowing function. During relaxing, nothing swallowing and water-swallowing conditions, the peak amplitudes of sEMG were considerably increased in both groups relevant to those of their individual pre-treatment (P<0.05)．The swallowing function score, and maximum amplitudes of sEMG during relaxing, nothing swallowing and water-swallowing conditions were significantly higher in the treatment group than in the control group (P<0.05), suggesting a better efficacy of intradermal needle-embedding treatment. CONCLUSION: Intradermal needle-embedding can significantly improve the swallowing function of stroke patients with dysphagia.

Effect of Catgut Implantation on Spatial Learning-memory Ability, Expression of Hippocampal Protein Kinase C Interacting Protein 1 and GluR 2 and Ca2+ Content in Rats with Chronic Ischemic Cognitive Impairment / 针刺研究

OBJECTIVE: To observe the effect of catgut embedment at "Baihui" (GV 20), "Dazhui" (GV 14), etc. on learning-memory ability, expression of hippocampal protein kinase C interacting protein 1 (PICK 1) and glutamate receptor 2 (GluR 2) proteins and level of calcium ions, so as to explore its mechanism underlying improvement of vascular cognitive impairment. METHODS: A total of 56 male SD rats were randomly divided into sham operation, model, catgut embedment and medication groups (n=14 in each). The chronic ischemic cognitive impairment model was established by permanent occlusion of bilate-ral common carotid arteries. The catgut embedment was applied to GV 20, GV 14, "Shenshu" (BL 23) and "Xuanzhong" (GB 39), once a week, for 4 weeks. Rats of the medication group received intraperitoneal injection of monosialate tetrahexose ganglioside sodium (GM-1, 0.33 mg/kg), once daily for 4 weeks. The rats' learning-memory ability was detected by Morris water maze tasks, pathological changes of hippocampal Nissl's bodies were tested by Nissl staining. The expression levels of PICK 1 and GluR 2 proteins in the hippocampus were detected by Western bolt (WB), and the concentration of calcium ions in the hippocampus tissue was measured by Bicinchoninic acid (BCA) assay. RESULTS: After modeling, the mean escape latencies of place navigation test were significantly increased while the crossing times of target platform quadrant of space probing test notably decreased in the model, catgut embedment and medication groups compared with their own individual pre-modeling (P0.05). CONCLUSION: Catgut implantation at GV 20 etc. can effectively improve the learning-memory ability in rats with chronic ischemic cognitive impairment, which may be related to its effects in down-regulating the expression of PICK 1 and calcium ion concentration and up-regulating the expression of AMPA receptor subunit GluR 2 protein in the hippocampus.

Effect of different types of dressings on early puncture site infection after peritoneal dialysis catheter implantation / 局解手术学杂志

Objective To explore the influence of dressings( occlusive and semi-occlusive) on puncture site infection of patients with peritoneal dialysis. Methods The clinical data of 2458 patients who underwent peritoneal dialysis and dressings in our hospital from January 2006 to January 2015 were collected. According to the type of dressings( occlusive or semi-occlusive) ,the patients were respectively divided into occlusive dressing group(2031 cases) and semi-occlusive dressing group (427 cases). The relationship between the two variants was an-alyzed with χ2 and the difference between the two groups was analyzed with the Logistic regression model. Results Among the 2,458 patients who underwent catheter placement,1778 patients (72. 25％) were subjected to open operation, 598 patients(24. 32％) were subjected to special trocar,81 patients (3. 29％) were subjected to laparoscopy and 3 patients (0. 12％) were subjected to embedded catheter. Through univariate analysis, OR of occlusive dressing was 2. 17 with 95％CI (0. 8～5. 74). After variant adjustment,OR of occlusive dressing group was 2. 15 (95％CI 0. 81～5. 70). The incidence of infection at the puncture site was unaffected by the type of dressing used. The combined results of puncture site infection and tunnel infection showed no significant difference between the two groups ( OR 1. 46, 95％CI 0. 72 ～2. 97). For the independent predictive factor on the ppuncture site of patients over 65 years old,OR was 2. 04, 95％CI (1. 25～3. 30). Con-clusion The type of dressings( occlusive and semi-occlusive) used after insertion of catheter during peritoneal dialysis has no influence on the early infection of puncture site,but the occlusive dressing is more suitable for clinical application due to less adverse reaction,easy opera-tion,low material cost and less workload on the nurses.

New and probable ultrastructural criteria for identification of cytoplasmic sol ­ gel states / Nuevo y probable criterio ultraestructural para la identificación de los estados citoplasmáticos sol ­ gel

In embedment-free transmission electron microscopy without employing epoxy embedding media, the cytoplasmic matrix, in which cell organelles and elements including the cytoskeletons are held in place, lattices of strands are clearly and constantly disclosed in every cell. Their compactness is variable in different kinds of cells and in different domains of one and the same cell, and it is changeable under hypo- or hyper-osmolarity. In addition, the appearance of strand-lattices is duplicable in artificial proteins at different sol/gel states and concentrations. All taken together, a new and probable ultrastructural criteria has been proposed for identification of cytoplasmic sol/gel states with a hope that the dynamic properties of the cell is understood not only by the cytoskeleton but also by the sol/gel states of cytosolic proteins and their concentration in distinct association with cellular ultrastructural entities.

En microscopía electrónica de transmisión, la inclusión-libre sin el uso de medios de inclusión epoxi, la matriz citoplasmática (los orgánulos celulares y elementos, incluyendo los citoesqueletos) se mantienen en su lugar y las redes de hebras aparecen claramente y constantemente en cada célula. Su tamaño compacto es variable en diferentes tipos de células y en diferentes dominios de una y la misma célula, y es modificable bajo hipo o hiper-osmolaridad. Además, la aparición de redes de hebras es duplicable en las proteínas artificiales en diferentes estados de concentraciones sol / gel. En este contexto se ha propuesto un criterio ultraestructural nuevo y probable para la identificación de los estados sol / gel citoplasmáticos, con el objetivo de que las propiedades dinámicas de la célula se comprendan no solo a partir del citoesqueleto, sino también a partir de los estados sol / gel de proteínas citosólicas y su concentración en relación con una asociación indistinta con las entidades celulares ultraestructurales.

Practice and model of embedded subject service for research in nursing science in hospital library / 中华医学图书情报杂志

After the practical experiences with embedded subject service for research in nursing science in Library , The First Affiliated Hospital of Chongqing Medical University was described , such as constructing and recommending resources for nursing staff , helping them to search and read related resources , providing training service of how to write and submit papers , the models of embedded subject service for research in nursing science were summarized , such as laying equal stress on construction and recommendation of resources , systematic service in the embedding processes , and tackling problems by groups in coordination .

Embedment of professional knowledge into literature retrieval course of traditional Chinese medicine / 中华医学图书情报杂志

The online teaching quality assessment system that was established by embedding the professional knowledge into the teaching of literature retrieval course, can help the students master the methods and skills to ac-cess and use the literature information they need and the basic knowledge of subjects in which they major .

Value of long-term embedment of thick needle at Tanzhong point (膻中穴) in weaning from mechanical ventilation in patients with chronic obstructive pulmonary disease / 中国中西医结合急救杂志

0.05).The successful rates of weaning from MV of embedment group(60%,75%) were significantly higher than those of control group(30%,35%) and traditional needle group(25%,30%) in the 2 nd and 4 th week after treatment(all P