A Case of Small Cell Neuroendocrine Carcinoma in the Parotid and Lacrimal Glands

Small cell carcinoma is most frequently found in the lung. Extrapulmonary sites of this neoplasm account for only 4% of all small cell carcinomas. Small cell carcinomas arising in the salivary glands are extremely rare, accounting for less than 1% of all parotid gland carcinomas. A 72-years- old women visited our clinic to evaluate hard protruding masses in the left preauricular region and the left orbit. Superficial parotidectomy and incisional biopsy for orbital mass revealed small cell neuroendocrine carcinoma. As the extrapulmonary small cell neuroendocrine carcinoma, arising in both left parotid and lacrimal glands is reported rarely in the world and not reported in Korea yet, we report its clinical progress.