The Neutrophil to Lymphocyte Ratio: An Emerging Diagnostic Biomarker for Parainflammation

The present century health care system has made great innovations for the diagnosis and treatment of diseases. Despite this, the diagnosis of parainflammation is difficult due to absence of symptoms in individuals. The development of diseases could generally be mitigated by early detection and control of parainflammation since it appears to be a unifying factor for infectious and non-infectious diseases. The present review describes the value of the neutrophil to lymphocyte ratio as a biomarker for the detection of parainflammation in disease asymptomatic (apparently healthy) individuals

Attributional Style in Healthy Persons: Its Association with 'Theory of Mind' Skills

OBJECTIVE: Attributional style, especially external personal attribution bias, was found to play a pivotal role in clinical and non-clinical paranoia. The study of the relationship of the tendency to infer/perceive hostility and blame with theory of mind skills has significant theoretical importance as it may provide additional information on how persons process social situations. The aim of this study was whether hostility perception bias and blame bias might be associated with theory of mind skills, neurocognition and emotional factors in healthy persons. METHODS: Total 263 participants (133 male and 130 female) were recruited. The attributional style was measured by using the Ambiguous Intentions Hostility Questionnaire (AIHQ). Participants were requested to complete a Brune's Theory of Mind Picture Stories task, neurocognitive task including Standard Progressive Matrices (SPM) and digit span, and other emotional dysregulation trait scales including Rosenberg's self-esteem, Spielberg's trait anxiety inventory, and Novaco anger scale. RESULTS: Multiple regression analysis showed that hostility perception bias score in ambiguous situation were found to be associated with theory of mind questionnaire score and emotional dysregulation traits of Novaco anger scale. Also, composite blame bias score in ambiguous situation were found to be associated with emotional dysregulation traits of Novaco anger scale and Spielberg's trait anxiety scale. CONCLUSION: The main finding was that the attributional style of hostility perception bias might be primarily contributed by theory of mind skills rather than neurocognitive function such as attention and working memory, and reasoning ability. The interpretations and implications would be discussed in details.

Serum levels of apolipoproten A-l and apolipoprotein B in healthy persons

Serum levels of apolipo protein A-I (Apo A-I) and apolipo protein B (Apo B) were determined with immumo turbidimetry technique on 42 healthy subjects. Obtained Apo AI values were distributed according to standard Gauss rule. Apo AI values were determined in the interval of 87-94 mg/dl, and Apo B- 57.112 mg/dl. There was no difference between male and female subjects in terms of serum levels of Apo B and Apo A-I. The results could be approved temporarily as reference for laboratory and clinical works