Spectral domain oct patterns of macular edema associated with branch retinal vein occlusion in Indian Eyes.

Aim : To study the spectral domain optical coherence tomography (sd-oct) characteristics of macular edema in branch retinal vein occlusion. Methods : 39 patients with branch retinal vein occlusion were studied with sd-oct . Characteristics analyzed were - integrity of inner segment outer segment junction, integrity of external limiting membrane, central retinal thickness and presence or absence of serous macular detachment. Results : 30 patients had disrupted photoreceptor Inner Segment-Outer Segment integrity. ( 76.9 %). External Limiting Membrane was disrupted in 64.2 % patients ( n=25 ). Serous macular detachment was present in 20. 5% patients. Average central retinal thickness was 363.84 microns. Conclusions : Spectral domain oct characteristics can help to predict the visual outcome in patients with macular edema due to branch retinal vein occlusion.

The Efficacy of Vaccinium Uliginosum for Early Age-Related Macula Degeneration

PURPOSE: To evaluate the effect of Bog Bilberry (Vaccinium uliginosum) extract in eyes with early age-related macular degeneration (AMD). METHODS: Forty-four eyes of forty four patients with early AMD were included in this randomized, double-blinded, and placebo-controlled study. All participants were randomly assigned to either the placebo group (n = 24), or the bog bilberry extract group (n = 20). Before drug administration, an ophthalmic examination which included slit lamp microscopy, best corrected visual acuity, and intraocular pressure was performed, and repeated 1and 3 months after treatment. Objective scatter index, glare and tear film break-up time were checked by Optical Quality Analysis System (OQAS, Visiometrics, Spain) and drusen volume, central macular thickness, and RPE and IS/OS junction thickness were investigated with spectral-domain optical coherence tomography (Spectralis, Heidelberg, Germany). RESULTS: In the bog bilberry extract group, RPE and IS/OS junction thickness was significantly increased compared to the placebo group after 3 months of drug administration. CONCLUSIONS: Bog Bilberry extract may play a favorable role in preventing the atrophic change of RPE and IS/OS junction layer and the progression of early macular degeneration.