A new phenylethanoid glycoside from roots of Incarvillea compacta / 中草药

Objective: To study the chemical constituents from the roots of Incarvillea compacta (Tibetan medicine). Methods: The constituents were isolated and purified by silica gel, Sephadex LH-20, ODS column chromatography, and preparative HPLC. Their structures were elucidated on the basis of their physicochemical properties and spectral data. Results: Four phenylethanoid glycosides were obtained from the ethanol extract in the roots of I. compacta and identified as Z-3‴-O-methylisocrenatoside (1), 3‴-O-methylcrenatoside (2), crenatoside (3), and isomartynoside (4), respectively. Conclusion: Compound 1 is a new phenylethanoid glycoside and compounds 2-4 are isolated from the plants of Incarvillea A. Juss. for the first time.