Résumé
No abstract available.
Sujets)
Pustulose exanthématique aigüe généralisée , Poulets , Consommation alimentaire , Hémodynamique , LaqueRésumé
Acute generalized exanthematous pustulosis (AGEP) is a rare disease characterized by multiple acute, small, non-follicular, sterile pustules on an erythematous background, usually accompanied by fever and leukocytosis. AGEP is attributed to systemic drugs, mainly beta-lactam and macrolide antimicrobials, in more than 90% of cases. Systemic contact dermatitis is not rare after ingesting lacquer broth, but few reported cases of AGEP have occurred after the ingestion of lacquer chicken broth without a past history of drugs, viral infection, or contact allergy to mercury. Here, we report a rare case of AGEP with a pattern of septic shock induced by the intake of lacquer chicken in a 40-year-old male patient. He developed a generalized pustular lesion with high fever and hypotension. Histologic examination showed subcorneal neutrophilic pustules, papillary dermal edema, and lymphohistiocytic perivascular infiltrates with some eosinophils and neutrophils. The patient was treated with empirical antibiotics and systemic steroids, and the pustular lesions improved 2 weeks later without recurrence.
Sujets)
Adulte , Humains , Mâle , Pustulose exanthématique aigüe généralisée , Antibactériens , Poulets , Eczéma de contact , Consommation alimentaire , Oedème , Granulocytes éosinophiles , Fièvre , Hypersensibilité , Hypotension artérielle , Laque , Hyperleucocytose , Granulocytes neutrophiles , Maladies rares , Récidive , Choc septique , StéroïdesRésumé
Lacquer has been widely used for decorating or protecting furniture, floors, tea-pots and ornaments in East Asia (Korea, Japan and China), and it is a common cause of contact dermatitis that occurs after direct skin contact. Lacquer chicken broth has been considered as a folk medicine or health food in East Asia, and especially in Korea. Thus, systemic contact dermatitis accompanied by cutaneous eruptions and systemic symptoms is not uncommon after ingesting lacquer chicken broth. The clinical manifestations of systemic contact dermatitis by ingesting lacquer chicken broth are mainly maculopapular eruptions (65%), erythema multiforme-like eruptions (32%) and erythrodermic eruptions (19%) and these lesions can also present in the form of pustules, purpuras, wheals and blisters. However, there are few reported cases of acute generalized exanthematous pustulosis (AGEP) occurring after ingesting lacquer chicken broth without a past history for drugs, viral infection and contact allergy to mercury. We herein describe a case of AGEP accompanied by erythema multiforme-like lesions occurringafter ingesting lacquer chicken broth in a 64-year-old female patient.
Sujets)
Femelle , Humains , Adulte d'âge moyen , Pustulose exanthématique aigüe généralisée , Cloque , Poulets , Eczéma de contact , Consommation alimentaire , Érythème , Extrême-Orient , Sols et revêtements , Nourriture biologique , Hypersensibilité , Architecture d'intérieur et mobilier , Japon , Corée , Laque , Médecine traditionnelle , Purpura , PeauRésumé
Acute generalized exanthematous pustulosis (AGEP) is an acute pustular eruption characterized by multiple small, sterile, non-follicular pustules on an erythematous and edematous base, usually accompanied by fever and neutrophilia. It is attributed to systemic drugs in over 90% of cases, mainly beta-lactam and macrolide antimicrobials. Viral infections, mercury exposure, Ginkgo biloba, and spider bites may occasionally cause the condition. We report a rare case of AGEP induced by intake of lacquer chicken in a 40-year-old man.