A case report on incidental finding of thymoma as anterior mediastinal mass

Thymomas are rare tumors in the anterior mediastinum, representing 50% of anterior mediastinal masses and about 20-30% of all mediastinal tumors. They are of unknown etiology; about 50% of patients with thymomas are diagnosed incidentally with chest radiography. Thymoma is classified into different stages, which determine the prognosis and type of management, the standard primary treatment for these tumors is Thymectomy. We present a case of 55-year female presented with shortness of breath, cough with expectoration and fever for past ten days. Chest x-ray revealed mediastinal widening. CECT chest showed a well-circumscribed heterogeneous solid enhancing mass lesion. FNAC was planned that showed features in favour of thymoma. Biopsy was done that confirmed lymphocyte rich type B thymoma.

Langerhans Cell Histiocytosis Presenting as Isolated Mediastinal Mass in an Infant.

Background: Isolated mediastinal involvement in Langerhans cell histiocytosis (LCH) has been rarely reported. Case characteristics: A 3-month-old boy presented with history of low grade intermittent fever, cough and noisy breathing for 2 weeks. Observation: A chest X-ray showed massive mediastinal widening. Biopsy of the mass confirmed LCH. Outcome: Patient is doing well after one year of treatment with LCH III protocol. Message: Langerhans cell histiocytosis should be considered in differential diagnosis of mediastinal mass in infants.