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Korean Journal of Otolaryngology - Head and Neck Surgery ; : 453-456, 2009.
Article Dans Coréen | WPRIM | ID: wpr-647107

Résumé

Leptomeningeal carcinomatosis is defined as the diffuse infiltration of the leptomeninges by malignant cells metastasized from systemic cancer. We report a case of leptomeningeal carcinomatosis presenting bilateral sensorineural hearing loss and dizziness. A 51-year-old woman who was diagnosed with non-small cell lung cancer with leptomeningeal carcinomatosis was referred to our department because of progressive hearing loss and dizziness. Magnetic resonance imaging revealed an abnormal enhancement of the vestibulocochlear nerves within the internal auditory canals bilaterally. The patient received chemotherapy concurrently with an intrathecal methotrexate injection. Leptomeningeal carcinomatosis must be considered in the differential diagnosis of cancer patients with bilateral progressive sensorineural hearing loss.


Sujets)
Femelle , Humains , Adulte d'âge moyen , Carcinomes , Carcinome pulmonaire non à petites cellules , Diagnostic différentiel , Sensation vertigineuse , Ouïe , Perte d'audition , Surdité bilatérale partielle , Surdité neurosensorielle , Imagerie par résonance magnétique , Méningite carcinomateuse , Méthotrexate , Nerf vestibulocochléaire
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