A new nortriterpenoid from Sambucus williamsii / 中草药

Objective: To study the chemical constituents in 60% ethanol extract from the stems of Sambucus williamsii. Methods: Six compounds were isolated and purified by macroporous resin D-101, silica gel, Sephadex LH-20, Toyopearl HW-40, ODS column chromatographies, and RP-HPLC. Results: Their structures were elucidated by spectroscopic methods and identified as 23-hydroxy-3-oxo-28-nor-12, 16-dien oleanane (1), 3-oxo-oleanolic acid (2), oleanolic acid (3), betulinic acid (4), palmitic acid (5), and 1-octacosanol (6). Conclusion: Compound 1 is a new nortriterpenoid named sambucusan A. Compounds 2 and 6 are isolated from this plant for the first time.