Perfil de óbitos associados à trauma abdominal submetidos ao instituto médico-legal do município de Toledo ­ Pr / Profile of deaths associated with abdominal trauma submitted to the medical-legal institute of the municipality of Toledo ­ Pr / Perfil de muertes asociadas a trauma abdominal presentado al instituto médico-legal del municipio de Toledo ­ Pr

Introdução: Os traumas abdominais representam notável importância dentre as causas predominantes de morbi-mortalidade no mundo. Em se tratando de óbitos relacionados a essas lesões, estão na categoria de causas externas, as quais no Brasil representam a segunda causa geral de mortalidade, principalmente na população em idade ativa. Notadamente, traumas estão fortemente relacionados a acidentes automobilísticos, cujas taxas vêm crescendo nos últimos anos. Neles, ocorrem os politraumas, cuja região abdominal é inclusa de forma prevalente. Objetivo: a presente pesquisa tem como objetivo apresentar o perfil de óbitos os quais sejam associados a trauma abdominal e submetido ao Instituto Médico-Legal, entre os anos de 2019 até 2021. Metodologia: estudo retrospectivo, do tipo transversal, de caráter fundamentalmente quantitativo, no qual foram avaliados os laudos de óbitos decorrentes de trauma abdominal necropsiados no IML de Toledo (PR), no período de 2019 a 2021. Foram avaliadas as variáveis sexo, idade, tipo de lesão, circunstância dos óbitos e órgão mais acometido. Resultados e discussão: dos 916 óbitos trazidos à Polícia Científica de Toledo (PR) advindos de causas externas, os inclusos dentre os traumas abdominais representaram um percentual de 51,05% (n=462), no período de 2019 a 2021. Observou-se maior prevalência de óbitos por acidentes automobilísticos (68,61%), cuja causa principal foi o politrauma (37,45%). O sexo masculino fora o mais prevalente, com 84,85% (n=392), cuja faixa etária teve concentração entre os 18 aos 29 anos. Os órgãos mais lesionados foram o fígado (69,31%) e o baço (33,66%). Considerações finais: nesta amostra houve predominância de óbitos por acidentes, principalmente associados ao trauma contuso, em homens na faixa entre 18 e 29 anos, cujo órgão mais lesado fora o fígado. O conhecimento acerca do perfil de óbitos é uma importante ferramenta epidemiológica frente a possíveis intervenções, além de servir como fonte estatística para outros trabalhos do âmbito médico-legal.

Introduction: Trauma represents a notable importance among the predominant causes of morbidity and mortality in the world. When it comes to deaths related to these injuries, they are in the category of external causes, since in Brazil they represent the second general cause of mortality, especially in the working-age population. Notably, traumas are strongly related to car accidents, whose rates have been increasing in recent years. In them, polytraumas occur, whose abdominal region is prevalently included. Objective: this research aims to present the profile of deaths which are associated with abdominal trauma and hospitalized at the Instituto Médico-Legal, between the years 2019 to 2021. Methodology: retrospective, cross-sectional study, fundamentally quantitative, in which the reports of deaths resulting from abdominal trauma necropsied at the IML of Toledo (PR), from 2019 to 2021, were evaluated. The variables were gender, age, type of injury, injuries of the deaths and most affected organ. Results and removal: Of the 916 deaths brought to the Scientific Police of Toledo (PR) from external causes, those included among abdominal traumas represented a percentage of 51.05% (n=462), in the period from 2019 to 2021. there was a higher prevalence of deaths from car accidents (68,61%), whose main cause was polytrauma (37.45%). Males were the most prevalent, with 84.85% (n=392), whose age group was concentrated between 18 and 29 years. The most injured organs were the liver (69.31%) and the spleen (33.66%). Final considerations: in this sample there was a predominance of deaths from accidents, mainly associated with blunt trauma, in men aged between 18 and 29 whose most injured organ outside the liver. Knowledge about the profile of deaths is an important epidemiological tool in the face of possible interventions, in addition to serving as a statistical source for other studies in the medical-legal field.

Introducción: El traumatismo abdominal representa notable importancia entre las causas predominantes de morbimortalidad en el mundo. Cuando se trata de muertes relacionadas con estas lesiones, se encuentran en la categoría de causas externas, que en Brasil representan la segunda causa general de mortalidad, especialmente en la población en edad de trabajar. En particular, el trauma está fuertemente relacionado con los accidentes automovilísticos, cuyas tasas han aumentado en los últimos años. En ellos se producen politraumatismos, cuya región abdominal está predominantemente incluida. Objetivo: esta investigación tiene como objetivo presentar el perfil de las muertes asociadas a traumatismo abdominal y presentadas al Instituto Médico Legal, entre los años 2019 y 2021. Metodología: estudio retrospectivo, transversal, de carácter fundamentalmente cuantitativo, en el que se analizaron los reportes de muertes. resultantes de trauma abdominal autopsiado en el IML de Toledo (PR), de 2019 a 2021. Se evaluaron las variables sexo, edad, tipo de lesión, circunstancias de las muertes y órgano más afectado. Resultados y discusión: de las 916 muertes aportadas a la Policía Científica de Toledo (PR) por causas externas, las incluidas dentro de los traumatismos abdominales representaron un porcentaje del 51,05% (n=462), en el periodo 2019 a 2021. observado- hubo mayor prevalencia de muertes por accidentes automovilísticos (68,61%), cuya principal causa fue el politraumatismo (37,45%). El sexo masculino fue el de mayor prevalencia, con 84,85% (n=392), cuyo grupo etario se concentró entre 18 y 29 años. Los órganos más lesionados fueron el hígado (69,31%) y el bazo (33,66%). Consideraciones finales: en esta muestra hubo predominio de muertes por accidentes, principalmente asociados a traumatismos cerrados, en hombres con edades entre 18 y 29 años, cuyo órgano más lesionado fue el hígado. El conocimiento sobre el perfil de defunciones es una importante herramienta epidemiológica de cara a posibles intervenciones, además de servir como fuente estadística para otros trabajos médico-legales.

Perfil epidemiológico da violência contra mulheres no estado da Paraíba de 2009 a 2019 / Epidemiological profile of violence against women in the state of Paraíba from 2009 to 2019

O objetivo desse estudo é traçar o perfil epidemiológico das notificações de violência contra a mulher no estado da Paraíba, no período de 2009 a 2019. Trata-se de um estudo transversal, descritivo, realizado por meio de consulta online ao Sistema de Informação TabNet na seção de Doenças e Agravos de Notificação através do campo violência interpessoal. Como parte dos resultados, identificamos que a violência mais frequente é a física, 45,2%. Foi observado que o maior número de queixas envolve mulheres negras, com 60,11% dos casos; na faixa etária de 20 a 29 anos, 22,71%; com ensino fundamental incompleto, 14,21%. Ademais, 59,2% das situações de violência contra a mulher ocorrem, predominantemente, em locais residenciais. Quanto aos encaminhamentos ao setor de saúde, os achados revelam que, nesse item, em 54,15% dos registros é definido como ignorado. O estudo apontou uma grande fragilidade nos registros de dados sobre violência, tanto pela falta de informações quanto pelo preenchimento inadequado das fichas. Por isso, é crucial reforçar a importância do preenchimento adequado das fichas de notificação compulsória e a qualificação dos profissionais para fornecer evidências precisas sobre o problema e subsidiar a gestão para os enfrentamentos.

This study aims to trace the epidemiological profile of notifications of violence against women in the state of Paraíba from 2009 to 2019. This cross-sectional, descriptive study conducted an online consultation of the TabNet Information System in the Diseases and Notifiable Diseases section through the field of interpersonal violence. As part of the results, we identified that the most frequent form of violence was physical violence (45.2%). We found that the highest number of complaints involved black women, with 60.11% of cases; in the 20-29 age group, 22.71%; and with incomplete primary education, 14.21%. In addition, 59.2% of situations of violence against women occur predominantly in residential areas. As for referrals to the health sector, the findings reveal that 54.15% of the records were defined as ignored. The study pointed to a significant weakness in the recording of data on violence, both due to the lack of information and the inadequate filling out of forms. For this reason, it is crucial to reinforce the importance of correctly filling out compulsory notification forms and training professionals to provide accurate evidence of the problem and support management in dealing with it.

Estudo das prescrições de psicotrópicos dispensados em uma farmácia básica do sertão paraibano / Study of psychotropic prescriptions dispensed in a basic pharmacy in the hinterland of Paraíba

O uso indiscriminado de psicotrópicos tem importância econômica, social e requer atenção dos profissionais de saúde. Nessa perspectiva, a pesquisa tem como objetivo avaliar a prescrição e o perfil de utilização de psicotrópicos na Farmácia Básica do município de Catolé do Rocha/PB. O presente estudo é transversal, quantitativo do tipo descritivo. A coleta de dados foi realizada por meio de questionários aplicados no período de abril a maio de 2021. Foram entrevistados 200 usuários, selecionados com base em critérios de inclusão e exclusão. Os resultados apontaram a prevalência do sexo feminino (63,0%), casados (53,5%), residentes da zona urbana (70,5%), baixa escolaridade (56,5%) e aposentados (44,5%). Em suma, as prescrições eram obtidas em UBS (81,0%) por queixas de ansiedade (24,0%) e insônia (23,5%). Observou-se maior frequência de prescrição para clonazepam (18,6%) e alprazolam (15,9%), ambos considerados MPI. Estes foram prescritos principalmente por clínicos gerais (71,8%). Assim, evidencia-se a importância do farmacêutico na APS, tanto na sensibilização dos prescritores com relação à escolha e prescrição adequada destes medicamentos quanto na orientação dos pacientes com vistas à promoção do uso racional de psicotrópicos.

The use of psychotropic drugs has economic and social importance and requires attention from health professionals. he objective of this research was to evaluate the prescription and the profile of use of psychotropic drugs in the Basic Pharmacy in the municipality of Catolé do Rocha/PB. This is a cross-sectional, quantitative, descriptive study. Data collection was carried out through questionnaires applied from April to May 2021. Two hundred users were interviewed, selected based on inclusion and exclusion criteria. The results showed a prevalence of females (63.0%), married (53.5%), residing in the urban area (70.5%), with low education (56.5%), and retired (44.5%). The prescriptions were obtained at the Basic Health Unit (81.0%) for complaints of anxiety (24.0%) and insomnia (23.5%). We observed a higher frequency of prescriptions for clonazepam (18.6%) and alprazolam (15.9%), both considered potential inappropriate drugs. These were mainly prescribed by general practitioners (71.8%). Thus, the importance of pharmacists in Primary Health Care is evident both to increase the awareness among prescribers regarding the choice and proper prescription of medications and to guide patients with a view to promoting the rational use of psychotropic drugs.

Equipe de enfermagem das unidades básicas de saúde na fronteira franco brasileira / Nursing team from basic health units on the Franco-Brazilian border

Objetivo: O estudo teve como objetivo traçar o perfil da equipe de enfermagem que atuam nas unidades básicas de saúde no município de Oiapoque, identificando as variáveis socioeconômica e demográfica, nível de formação profissional e o seu aperfeiçoamento no processo de trabalho. Métodos: Tratou-se de uma pesquisa descritiva transversal, com abordagem quantitativa, composta pelos técnicos e enfermeiros que trabalham nas cinco unidades básicas de saúde em funcionamento no município de Oiapoque, feita através de um questionário aplicado individualmente. Resultados: Os resultados obtidos constataram que a maioria dos pesquisados; encontra-se numa faixa etária entre 31 a 35 anos (30%); são do sexo feminino (86%); técnicos de enfermagem (57%), seguido de enfermeiros (43%); possuem ensino superior (29%), pós-graduação (14%), atuação na profissão de 1 a 5 anos (42%), com vínculo contratual temporário (86%); e a principal dificuldade encontrada pelos profissionais é a falta de recursos matérias e equipamentos (56%). Conclusão: Espera-se que os resultados apresentados possam contribuir para melhores investimentos na formação e inserção do profissional da enfermagem nos cuidados primários de áreas transfronteiriças, visto que ainda há carência de profissionais qualificados, principalmente para prestar assistência em tais regiões com saúde singular.(AU)

Objective: The study aimed to outline the profile of the nursing team working in basic health units in the municipality of Oiapoque, identifying the socioeconomic and demographic variables, level of professional training and their improvement in the work process. Methods: This was a cross-sectional descriptive study, with a quantitative approach, composed of technicians and nurses working in the five basic health units operating in the municipality of Oiapoque, carried out through a questionnaire applied individually. Results: The results obtained found that the majority of those surveyed; is in an age range between 31 to 35 years (30%); are female (86%); nursing technicians (57%), followed by nurses (43%); have higher education (29%), postgraduate (14%), work in the profession from 1 to 5 years (42%), with temporary contractual relationship (86%); and the main difficulty encountered by professionals is the lack of material resources and equipment (56%). Conclusion: It is hoped that the results presented can contribute to better investments in the training and insertion of nursing professionals in primary care in cross-border areas, since there is still a shortage of qualified professionals, mainly to provide assistance in such regions with unique health.(AU)

El estudio tuvo como objetivo determinar el perfil del equipo de enfermería que trabaja en unidades básicas de salud en el municipio de Oiapoque, identificando como variables socioeconómicas y demográficas, el nivel de capacitación profesional y su mejora en el proceso de trabajo. Métodos: Esta es una investigación descriptiva transversal, con un enfoque cuantitativo, compuesta por técnicos y enfermeras que utilizan las cinco unidades básicas de salud que operan en el municipio de Oiapoque, realizadas mediante un cuestionario utilizado. Resultados: Los resultados obtenidos encontraron que la mayoría de los encuestados; tiene un rango de edad entre 31 y 35 años (30%); son mujeres (86%); técnicos de enfermería (57%), seguidos por enfermeras (43%); tener educación superior (29%), posgrado (14%), trabajar en la profesión de 1 a 5 años (42%), con relación contractual temporal (86%); La principal dificultad encontrada por los profesionales es la falta de recursos materiales y de equipo (56%). Conclusión: Se espera que los resultados mostrados puedan contribuir a mejores inversiones y capacitación de enfermería profesional en atención primaria en áreas transfronterizas, ya que todavía hay una escasez de profesionales calificados, principalmente para brindar asistencia en tales situaciones con una salud única.(AU)

Ensino, pesquisa e extensão em ginástica na região sul do Brasil: desenvolvimento e potencial crescimento / Teaching, research and extension in gymnastics at southern region of Brazil: development and potential growth / Enseñanza, investigación y extensión in gimnasia em la región sur de Brasil: desenvolvimiento y potencial crecimiento

Essa pesquisa estudou o perfil e a atuação acadêmi-ca de 31 docentes que atuam com o ensino da Ginástica em 20 Instituições de Ensino Superior (IES) públicas da região Sul do Brasil, por meio de pesquisa documental. Foi constatada atuação majoritária de não-especialistas, que tematizam principalmente as ginásticas competitivas em suas disciplinas. As ações extensionis-tas e as publicações e orientações de pesquisas específicas sobre a Ginástica são incipientes e concentradas nos docentes especialis-tas. Destaca-se uma IES, com resultado do esforço pessoal de uma docente. O estudo sugere uma contraditória fragilidade dessa área na região que deu origem ao desenvolvimento desses saberes e práticas no Brasil, em comparação com outras regiões do Brasil.

This research studied the profile and academic performance of 31 professors who work with Gymnastics teaching in 20 public Higher Education Institutions (HEIs) in the South region of Brazil through documentary research. Most non-specialists were found to be working, who mainly focused on competitive gymnastics in their disciplines. Extensionist actions and publications and specific research guidelines on Gymnastics are incipient and concentrated on specialist teachers. One HEI stands out because of the personal effort of a professor. The study suggests a contradictory fragility of this area in the region that gave rise to the development of this knowledge and practices in Brazil compared to other areas of Brazil.

Esta investigación estudió el perfil y el desempeño académico de 31 profesores que actúan en la enseñanza de la Gimnasia en 20 Instituciones de Educación Superior (IES) públicas de la región Sur de Brasil a través de una investigación documental. Se encontró que la mayoría de los profesores son no especialistas y enfocaban principalmente en la gimnasia competitiva en sus disciplinas. Las acciones y publicaciones extensionistas y lineamientos de investigación específicos sobre Gimnasia son incipientes y concentrados en docentes especialistas. Una IES destaca como resultado del esfuerzo personal de una docente. El estudio sugiere una fragilidad contradictoria de esta área en la región que dio lugar al desarrollo de estas prácticas en Brasil.

Ensino, pesquisa e extensão em ginástica na região sul do Brasil: desenvolvimento e potencial crescimento / Teaching, research and extension in gymnastics at southern region of Brazil: development and potential growth / Enseñanza, investigación y extensión in gimnasia em la región sur de Brasil: desenvolvimiento y potencial crecimiento

Essa pesquisa estudou o perfil e a atuação acadêmica de 31 docentes que atuam com o ensino da Ginástica em 20 Instituições de Ensino Superior (IES) públicas da região Sul do Brasil, por meio de pesquisa documental. Foi constatada atuação majoritária de não-especialistas, que tematizam principalmente as ginásticas competitivas em suas disciplinas. As ações extensionistas e as publicações e orientações de pesquisas específicas sobre a Ginástica são incipientes e concentradas nos docentes especialistas. Destaca-se uma IES, com resultado do esforço pessoal de uma docente. O estudo sugere uma contraditória fragilidade dessa área na região que deu origem ao desenvolvimento desses saberes e práticas no Brasil, em comparação com outras regiões do Brasil (AU).

This research studied the profile and academic performance of 31 professors who work with Gymnastics teaching in 20 public Higher Education Institutions (HEIs) in the South region of Brazil through documentary research. Most non-specialists were found to be working, who mainly focused on competitive gymnastics in their disciplines. Extensionist actions and publications and specific research guidelines on Gymnastics are incipient and concentrated on specialist teachers. One HEI stands out because of the personal effort of a professor. The study suggests a contradictory fragility of this area in the region that gave rise to the development of this knowledge and practices in Brazil compared to other areas of Brazil (AU).

Esta investigación estudió el perfil y el desempeño académico de 31 profesores que actúan en la enseñanza de la Gimnasia en 20 Instituciones de Educación Superior (IES) públicas de la región Sur de Brasil a través de una investigación documental. Se encontró que la mayoría de los profesores son no especialistas y enfocaban principalmente en la gimnasia competitiva en sus disciplinas. Las acciones y publicaciones extensionistas y lineamientos de investigación específicos sobre Gimnasia soni ncipientes y concentrados en docentes especialistas. Una IES destaca como resultado del esfuerzo personal de una docente. El estudio sugiere una fragilidad contradictoria de esta área en la región que dio lugar al desarrollo de estas prácticas en Brasil (AU).

Situación del ejercicio profesional del licenciado en instrumentación y área quirúrgica en Paraguay

Introducción: en Paraguay en 1996 se crea la Escuela de Instrumentación y Área Quirúrgica, vinculada a una universidad pública, a partir del 2008 se crean otras ofertas en el sector privado. El instrumentador quirúrgico puede desempeñarse como instrumentador, circulante, coordinador general de quirófanos y coordinador de la central de esterilización. Objetivo: conocer la situación del ejercicio profesional del licenciado instrumentador quirúrgico en Paraguay. Metodología: estudio descriptivo, cuantitativo y trasversal. La muestra es de 167 licenciados, egresados de instituciones pública y privadas. Muestreo no probabilístico por conveniencia, el instrumento de recolección de datos es un cuestionario electrónico. Resultados: el 74 % son mujeres, el 50 % presenta un rango de edad de 21 a 30 años, 79,6 % egresados de una institución pública, 40 % dice tener dificultad moderada para el primer empleo. El acceso al empleo, 71 % fue por contactos personales, el 72 % se dedica a instrumentar, el 60 % tiene una antigüedad laboral de 1 a 5 años. Entre los posgrados, el 30 % posee didáctica universitaria. Discusión: instrumentador quirúrgico, reúne las exigencias para ocupar otras funciones además de instrumentar y circular en el quirófano. Igualmente, en otros estudios se evidencia menor participación en el área administrativa, docencia, mercadeo y ventas. Han trascurrido 20 años del egreso de las primeras promociones, siendo una profesión novel, poco visualizado. Es de subrayar que el estado puede ahorrar recursos económicos al contratar a instrumentadores, puesto que son expertos en los cuidados asépticos y competentes en optimizar los tiempos quirúrgicos al que se expone el paciente.

Introduction: In Paraguay the school of Instrumentation and Surgical Area was created in 1996 linked to the National University, and in 2008 onwards other offers were created in the private sector. The Surgical Instrument Technician can work as instrumentalist, circulating nurse, general coordinator of operating rooms, and coordinator of the central sterilization unit. Objective: to know the work environment of the professional and licensed Surgical Instrument Technician in Paraguay. Methodology: descriptive, quantitative and cross-sectional study. The sample is 167 graduates, graduates of public and private institutions. Non-probability sampling for convenience, the data collection instrument is an electronic questionnaire. Results: 74% are women, 50% have an age range between 21 and 30 years old, 79.6% graduated from a public institution, 40% say they have moderate difficulty finding their first job in the field. Access to employment, 71% was through personal contacts, 72% is dedicated to work as Instrument Technicians, 60% have a job seniority of 1 to 5 years. Among the postgraduates, 30% are university didactics certified. Discussion: Surgical Instrument Technicians meet the requirements to perform other functions in addition to instrumentation and circulating nurses in the operating room. Similarly, other studies show less participation in the administrative area, teaching, marketing and sales. 20 years have elapsed since the first Technicians graduated, being a new profession, not given the importance it deserves. It is noteworthy that the state can save economic resources by hiring Surgical Instrument Technicians, since they are experts in aseptic care and competent in minimizing the amount of time the patient spends in surgery.

Internações na infância por doenças do aparelho respiratório no Brasil de 2013 a 2022 / Hospitalizaciones infantiles por enfermedades del sistema respiratorio en Brasil de 2013 a 2022 / Hospitalizations during childhood due to respiratory system diseases in Brazil from 2013 to 2022

Introdução: As doenças do sistema respiratório se mostram como uma das causas mais preocupantes de internações hospitalares no país. Nessa perspectiva, o perfil das internações por doenças respiratórias em crianças permite observar os parâmetros desta problemática, fornecendo um conhecimento amplo acerca do processo saúde e doença nessa população. Objetivo: Analisar o perfil epidemiológico das internações hospitalares por causas do aparelho respiratório em crianças de 0 a 9 anos no Brasil e regiões, entre os anos de 2013 e 2022. Metodologia: Trata-se de um estudo ecológico, realizado no Brasil, a partir de dados secundários do Sistema de Informações Hospitalares. A população escolhida para este estudo foram crianças de 0 a 9 anos deidade. Os dados foram coletados em 26 de novembro de 2022. As variáveis dependentes do estudo são as internações de crianças de 0 a 9 anos por doenças do aparelho respiratório no Brasil e suas regiões. Já, como variáveis independentes, tem-se o tempo, do período de janeiro de 2013 a setembro de 2022, regiões e faixa etária. Resultados: Há uma tendência de queda das internações por causa respiratória até o ano de 2016, seguido de um crescimento gradativo até 2019. Entretanto, em 2020, a taxa de hospitalização reduziu drasticamente em todas as localidades. As regiões Sul, Norte e Centro-Oeste permaneceram com taxas maiores que o Brasil em todo o período estudado. A internação em menores de 1 ano representa o maior quantitativo de internações sendo a pneumonia a causa mais prevalente. Conclusões: As taxas de internação infantil por doenças respiratórias representam importante preocupação para saúde pública. Assim, destaca-se a relevância da efetividade da Atenção Primária à Saúde, que possui grande impacto no desfecho dos adoecimentos em crianças, especialmente das doenças respiratórias (AU).

Introduction: Respiratory system diseases are one of the most worrying causes of hospital admissions in the country. From this perspective, the profile of hospitalizations for respiratory diseases in children allows us to notice the parameters of this problem, providing a broad understanding of the health and disease process in this population.Objective: To analyze the epidemiological profile of hospital admissions due to respiratory causes in children aged 0 to 9 in Brazil and its regions between 2013 and 2022. Methodology: This is an ecological study held in Brazil using secondary data from the Hospital Information System. The population chosen for this study consisted of children aged 0 to 9. Data were collected on November 26, 2022. The dependent variables of this study are hospitalizations of children aged 0 to 9 due to respiratory diseases in Brazil and its regions. The independent variables are time, from January 2013 to September 2022, regions, and age group.Results: There was a downward trend in hospitalizations due to respiratory causes until 2016, followed by a gradual increase until 2019. Nonetheless, in 2020, the hospitalization rate fell dramatically in all locations. The South, North and Mid-West regions remained with higher rates than Brazil throughout the studied period. Hospitalization of children under 1 year old represents the largest number of admissions, with pneumonia being Revista Ciência Plural. 2024; 10(1): e31414 3the most prevalent cause.Conclusions: Hospitalization rates during childhood due to respiratory diseases represent a major public health concern. Thus, one can highlight the importance of the effectiveness of Primary Health Care, which has a major impact on the outcome of illnesses in children, especially respiratory diseases (AU).

Introducción: Las enfermedades del sistema respiratorio son una de lascausas más preocupantes de hospitalizaciones en el país. Desde esta perspectiva, el perfil de hospitalizaciones por enfermedades respiratorias en niños permite observar los parámetros de este problema, proporcionando una amplia comprensión del proceso de salud y enfermedad en esta población.Objetivo: Analizar el perfil epidemiológico de las internaciones por causas respiratorias en niños de 0 a 9 años en Brasil y sus regiones entre 2013 y 2022. Metodología: Se trata de un estudio ecológico conducido en Brasil a partir de datos secundarios del Sistema de Información Hospitalaria. La población elegida para este estudio fueron los niños de 0 a 9 años. Los datos se recogieron el 26 de noviembre de 2022. Las variables dependientes del estudio son las hospitalizaciones de niños de 0 a 9 años por enfermedades respiratorias en Brasil y sus regiones. Las variables independientes son el tiempo, de enero de 2013 a septiembre de 2022, las regiones y la franja etaria.Resultados: Se nota una tendencia a la baja de las hospitalizaciones por causas respiratorias hasta 2016, seguida de un aumento gradual hasta 2019. Sin embargo, en 2020, la tasa de hospitalización cayó drásticamente en todas las localidades. Las regiones Sur, Norte y Medio Oeste se mantuvieron con tasas másaltas que Brasil durante todo el período estudiado. Las hospitalizaciones en niños menores de 1 año representan el mayor número de internaciones, siendo la neumonía la causa más prevalente.Conclusiones: Las tasas de hospitalización infantil por enfermedades respiratorias representan un importante problema de salud pública. Así, se subraya la importancia de la eficacia de la Atención Primaria de Salud, que tiene un gran impacto en el resultado de las enfermedades en los niños, especialmente las respiratorias (AU).

Marcos de Competência para a formação de enfermeiros no Brasil: revisão de escopo / Competency milestones for the training of nurses in Brazil: a scoping review / Hitos de competencia para la formación de enfermeros en Brasil: una revisión del alcance

O ensino superior em Enfermagem está em constante transformação, ensejando o uso de metodologias ativas que colaborem para o desenvolvimento de competências. Objetivou-se apresentar o panorama dos marcos de competência para formação de enfermeiros no Brasil. Trata-se de uma Revisão de Escopo, realizada nas bases de dados Biblioteca Virtual em Saúde (BVS), PubMed, Portal da Capes e Biblioteca Eletrônica Científica Online (SciELO), no período de 2012 a 2022. Foram utilizados os descritores "Educação Baseada em Competências", "Perfil de Competências de Enfermeiros"; "Educação do Enfermeiro" e "Competência" nos idiomas inglês e espanhol, com o booleano "AND". Os 11 estudos selecionados evidenciaram a mudança de paradigma de formação baseada em competências, a partir das Diretrizes Curriculares Nacionais, clareamento do conceito de competência e marco de competências. Na realidade brasileira o tema é incipiente, com iniciativas baseadas em perfis de competências de gestão, liderança, promoção e educação em saúde.

Higher education in Nursing is constantly changing, stimulating the use of active methodologies that contribute to the development of competencies. The objective was to present an overview of the competency milestones for nurse training in Brazil. This is a Scoping Review, carried out in the Virtual Health Library (VHL), PubMed, Capes, Portal and Scientific Electronic Library Online (SciELO) databases, from 2012 to 2022. The descriptors "Based Education Skills", "Profile of Nurses' Skills"; "Nurse Education" and "Competency" were used in English and Spanish, with the Boolean "AND". The 11 selected studies showed a change in the paradigm of competency-based training, using the National Curriculum Guidelines, clarifying the concept of competency and the competency milestones. In the Brazilian reality, the theme is incipient, with initiatives inscribed in records of management skills, leadership, promotion and health education.

La educación superior en Enfermería está en constante cambio, promovendo el uso de metodologías activas que contribuyan al desarrollo de competencias. El objetivo fue presentar un panorama de los hitos competenciales para la formación de enfermeros en Brasil. Se trata de una Revisión de Alcance, realizada en las bases de datos Biblioteca Virtual en Salud (BVS), PubMed, Portal Capes y Biblioteca Electrónica Científica en Línea (SciELO), de 2012 a 2022. Se utilizaron los descriptores "Educación Basada en Habilidades", "Perfil de Competencias del Enfermero"; "Educación de enfermería" y "Competencia" en inglés y español, con el booleano "AND". Los 11 estudios seleccionados evidenciaron un cambio en el paradigma de la formación por competencias, tomando como base los Lineamientos Curriculares Nacionales, aclarando el concepto de competencia y el marco de competencias. En la realidad brasileña, el tema es incipiente, con iniciativas inscritas en registros de habilidades de gestión, liderazgo, promoción y educación en salud.

Fatty acid composition and metabolic pathways in Arbacia dufresnii (Arbaciidae: Arbacioida) gametes: implications of shrimp byproducts in aquaculture feeds / Composición de ácidos grasos y vías metabólicas en los gametos de Arbacia dufresnii (Arbaciidae: Arbacioida) implicaciones de los subproductos de langostinos en los alimentos de acuicultura

Abstract Introduction: Care towards nutrition is essential for the quality of a sustainable aquaculture product. Since the balance in food affects the growth and production of gametes. The circular economy is made possible through the use of discarded materials. Objective: The aim of this research was to study the fatty acid composition and metabolic pathways in the gametes of Arbacia dufresnii, with a focus on the implications of incorporating shrimp byproducts into aquaculture feeds. Methods: Four different treatments were designed to maintain optimal nutritional quality, particularly in lipids and proteins, based on previous studies. The fatty acid profiles of the feeds and gametes were analyzed by using gas-chromatography, and statistical analyses were conducted to determine significant differences. Results: Significant differences were observed in the abundance (%) of omega-3 (ω-3) and omega-6 (ω-6) fatty acids. The (ω-3) metabolic pathway was more pronounced in the gametes of wild animals and those fed with the experimental feeds. In contrast, the (ω-6) metabolic pathway was less relevant in these groups. The (ω-3) /(ω-6) ratio was highest in the gametes of wild animals. Feeds enriched in fatty acids enhanced their bioaccumulation in the gametes reaching higher concentrations than wild animals. The availability of fatty acids in foods allowed their bioaccumulation in gametes, with concentrations equal to or higher than those observed in animals in their natural environment for certain fatty acids. Conclusions: Incorporating shrimp byproducts in aquaculture feeds demonstrated a promising strategy for resource utilization and organic input generation. The fatty acid composition in the gametes of A. dufresnii was influenced by the diet, highlighting the potential of balanced feeds to enhance the bioaccumulation of essential fatty acids. These findings provide valuable insights for the development of sustainable aquaculture practices and the production of nutritionally enriched seafood products.

Resumen Introducción: El cuidado hacia la nutrición es fundamental para la calidad de un producto acuícola sostenible. Ya que el balance en los alimentos afecta el crecimiento y producción de los gametos. A partir del aprovechamiento de materias de descarte se posibilita la economía circular. Objetivo: El objetivo de este estudio fue investigar la composición de ácidos grasos y las vías metabólicas en los gametos de Arbacia dufresnii, centrándose en las implicaciones de la incorporación de subproductos de camarones en los alimentos de acuicultura. Métodos: Se diseñaron cuatro tratamientos diferentes para mantener una calidad nutricional óptima, especialmente en lípidos y proteínas, basándose en estudios previos. Se analizaron los perfiles de ácidos grasos de los alimentos y los gametos mediante cromatografía de gases, y se realizaron análisis estadísticos para determinar diferencias significativas. Resultados: Se observaron diferencias significativas en la abundancia (%) de ácidos grasos omega-3 (ω-3) y omega-6 (ω-6). La vía metabólica de (ω-3) fue más pronunciada en los gametos de los animales en su entorno natural y aquellos alimentados con los piensos experimentales. Por el contrario, la vía metabólica de (ω-6) tuvo menos relevancia en estos grupos. La relación (ω-3) /(ω-6) fue más alta en los gametos de los animales en su entorno natural. La disponibilidad de ácidos grasos en los alimentos permitió su bioacumulación en los gametos, con concentraciones iguales o superiores a las observadas en los animales en su entorno natural para ciertos ácidos grasos. Conclusiones: La incorporación de subproductos de camarones en los alimentos de acuicultura demostró ser una estrategia prometedora para la utilización de recursos y la generación de insumos orgánicos. La composición de ácidos grasos en los gametos de A. dufresnii fue influenciada por la dieta, destacando el potencial de los alimentos balanceados para mejorar la bioacumulación de ácidos grasos esenciales. Estos hallazgos brindan información valiosa para el desarrollo de prácticas sostenibles en acuicultura y la producción de productos marinos enriquecidos nutricionalmente.

Epidemiological profile of patients with type 2 diabetes mellitus treated at a teaching-assistance unit in Northeast Brazil / Perfil Epidemiológico dos pacientes com diabetes tipo 2 atendidos em uma unidade docente-assistencial no nordeste brasileiro

Objective: To determine the epidemiological profile of patients with type 2 diabetes mellitus in a teaching unit. Method: In this observational, cross-sectional, and descriptive study, data from the medical records of consultations conducted between February 2020 and May 2022 at an endocrinology outpatient clinic in a teaching unit in Northeast Brazil were evaluated. A descriptive analysis of the data was performed, with percentage values, medians, and interquartile ranges (IQRs) reported. Result: Data were collected from the medical records of 118 patients, and the medical records of 95 patients were used for statistical analysis after the exclusion of records with insufficient data. Seventy patients (73.6%) were female, with a median age of 57 years (IQR 51.5-65), a median body mass index (BMI) of 28.9 kg/m2 (IQR 25.7-33.1) and a median age at diagnosis of 47.5 years (IQR 38-55). The median glycated hemoglobin (HbA1c) and fasting blood glucose levels during follow-up were 7.6% (IQR 6.6-9.7) and 132.8 mg/dL (IQR 113.5-201.7), respectively, and only 36.8% (n=35) of patients were within their HbA1C therapeutic target range. Approximately 73.6% (n=70) of the patients used statins, but only 18 (18.9%) had LDL-c within their therapeutic target range. Twenty-seven patients (28.4%) had kidney dysfunction, either albuminuria or a glomerular filtration rate (GFR) reduction, and 6 of them (22.2%) did not use any nephroprotective medication. Fewer than half of the patients underwent fundoscopy, and 32.5% of them showed some degree of retinopathy. Neuropathy was present in 33 patients (34.7%), with 3 patients (3.16%) presenting with amputations. Conclusion: Adequate glycemic control was achieved in just under half of the patients, and a relevant proportion of patients experienced microvascular complications. Strategies for the early detection of complications and more aggressive treatment of the disease and its comorbidities are necessary

Objetivo: Traçar o perfil epidemiológico de pacientes com Diabetes Tipo 2 de uma unidade docente-assistencial. Método: Estudo observacional, transversal e descritivo com dados de prontuário de consultas realizadas entre fevereiro de 2020 e maio de 2022 no ambulatório de endocrinologia de uma unidade docente-assistencial no nordeste brasileiro. Procedeu-se à análise descritiva dos dados, sendo informados os valores percentuais, mediana e intervalo interquartil. Resultado: De um total de 118 prontuários, foram analisados 95 pacientes após a exclusão daqueles com dados insuficientes. Destes, 73,6% (n=70) são do sexo feminino, com idade mediana de 57 anos (IIQ 51,5-65), mediana do IMC 28,9kg/m2 (IIQ 25,7-33,1) e idade ao diagnóstico de 47,5 anos (IIQ 38-55). As medianas da última HbA1C e glicemia em jejum foram 7,6% (IIQ 6,6-9,7) e 132,8 mg/dL (IIQ 113,5- 201,7), e apenas 36,8% (n=35) foram classificados como dentro da meta pela HbA1C. Cerca de 73,6% (n=70) dos pacientes utilizavam estatinas, mas somente 18 (18,9%) tinham LDL-c dentro da meta terapêutica. Vinte e sete pacientes (28,4%) apresentavam disfunção renal, seja albuminúria e/ou redução da TFG, e 6 (22,2%) não usavam nenhuma medicação nefroprotetora. Menos da metade dos pacientes realizou fundoscopia, e, destes, 32,5% apresentavam algum grau de retinopatia. Neuropatia está presente em 33 pacientes (34,7%), com 3 pacientes (3,16%) apresentando amputações. Conclusão: O controle glicêmico adequado foi obtido em pouco menos da metade dos pacientes e uma proporção relevante apresenta complicações microvasculares. Estratégias de detecção precoce de complicações e de tratamento mais agressivo da doença e suas comorbidades são necessárias

Biological Identification of Skulls in Indonesian and Thai Populations: Ancestry Estimation, Sex Determination, Stature Estimation, and Age Estimation / Identificación Biológica de Cráneos en Poblaciones de Indonesia y Tailandia: Estimación de Ascendencia, Determinación del Sexo, Estimación de Estatura y Estimación de Edad

SUMMARY: This review article will present an overview of biological profiles in forensic utilities. The biological profile of the skull in the existing literature can help to identify humans, especially if the condition of the victim found is a result of mutilation or a bomb explosion. When it comes to the precision of identifying skeletal remains, the human skull is frequently cited as being first in the estimation of age and ancestry and second in terms of sex and stature. It can be an alternative to assessing the following biological parameters: sex, age, stature, and ancestry. The implementation of biological profiles in the identification process is very important considering that some cases require the assistance of forensic anthropology. This review article shows the importance of the value of skulls. The method that can be applied is craniometry which can be used to determine sex, age, stature, and estimated ancestry. Different results will occur depending on the completeness of the skull. Therefore, estimation formulas have different accurate results. Discriminant function analysis has been performed on various measurement sets and its discriminant power has been validated by many researchers. Geometric morphometric analysis has become the main tool for shape analysis and many attempts have been made to use it in analyzing skulls. Several methods supported by technology have also been developed. It is hoped that the review article will show significant differences in results between studies in Thailand and Indonesia, even though they are in the same racial group.

Este artículo presenta una descripción general de los perfiles biológicos en las utilidades forenses. El perfil biológico del cráneo en la literatura existente puede ayudar a identificar a los humanos, especialmente si la condición en la que se encuentra la víctima es el resultado de una mutilación o la explosión de una bomba. Cuando se trata de la precisión en la identificación de restos óseos, el cráneo humano se cita con frecuencia como el primero en la estimación de edad y ascendencia y el segundo en términos de sexo y estatura. Puede ser una alternativa para evaluar los siguientes parámetros biológicos: sexo, edad, estatura y ascendencia. La implementación de perfiles biológicos en el proceso de identificación es importante considerando que algunos casos requieren la asistencia de la antropología forense. Este artículo de revisión muestra la importancia del valor de las cnezas óseas. El método que se puede aplicar es la craneometría para determinar el sexo, la edad, la estatura y la ascendencia estimada. Se pueden obtener diferentes resultados dependiendo de la integridad del cráneo. Por lo tanto, las fórmulas de estimación tienen resultados precisos diferentes. Se ha realizado un análisis de función discriminante en varios conjuntos de medidas y muchos investigadores han validado su poder discriminante. El análisis a través de la morfometría geométrica se ha convertido en la principal herramienta para el análisis de formas y se ha utilizado frecuentemente en el análisis de cráneos. También se han desarrollado varios métodos apoyados en la tecnología. Se espera que este trabajo muestre diferencias significativas en los resultados entre los estudios realizados en Tailandia e Indonesia, aunque pertenezcan al mismo grupo racial.

Early characterization of an adult population at an insurer's point of entry as an opportunity to identify hospitalization risk

Introduction: Health Benefit Plan Administrators must manage the health risk of their members. Therefore, health characterization is performed from enrollment to support decision-making and timely intervention. Objective: To analyze the historical results of characterizing the adult population on admission to the insurance company in relation to the demand for all-cause and psychiatric hospitalization services. Materials and Methods: An observational cross-sectional study with members over 18 years of age, in which an analysis was made of the characterization of the adult population of the insurer and its association with the use of medical consultation services in primary care and all-cause and psychiatric hospitalizations. Bivariate and multivariate analysis was made, and odds ratios (OR) were calculated in logistic regression. Results: Variables significantly associated with having an all-cause hospitalization were identified: having referred history of heart disease OR=1.71(95%CI: 1.33; 2.20), respiratory disease OR= 1. 30(95%CI: 1.04; 1.61), chronic kidney disease OR=1.66(95%CI: 1.13; 2.45), cancer OR=1.65(95%CI: 1.14; 2.40), taking any medication permanently OR=1.35(95%CI: 1.174; 1.56) and smoking OR=1.44(95%CI: 1.12; 1.85). For psychiatric hospitalizations, a history of discouragement, depression, or little hope was relevant with OR=5.12(95%CI: 1.89; 13.87). Discussion: The characterization of patients during enrolment allowed the identification of predictor variables of hospitalization, guiding management from the primary care level minimizing costs and catastrophic health events. Conclusion: The timely identification of specific patient profiles allows timely actions to minimize health costs and catastrophic health events.

Study on the current situation and latent profile analysis of nurses'voice behavior / 中华护理杂志

Objective To analyze the current situation and latent profiles of nurses'voice behavior in nurses,and explore the influencing factors of different types.Methods Through convenience sampling,812 nurses who worked in tertiary hospitals from 5 cities in Guangdong Province during April 2022 to June 2022 were recruited.The demographic questionnaire,the Voice Behavior Scale,the Humble Leadership Scale,and the Team Psychological Safety Climate Scale were used for investigation.Latent profile analysis was used to explore the latent profiles of nurses'voice behavior.The influencing factors of latent profiles were identified by multivariate Logistic regression.Results The total score of the voice behavior in 812 nurses is(37.04±5.88).Voice behaviors in nurses is divided into 3 latent classes,namely"conservation group"(27.83％),"balanced-risky group"(61.95％),and"the challenge group"(10.22％).The influencing factors include recruitment type,whether to assist in department management,humble leadership,team psychological safety climate(all P＜0.05).Conclusion The level of nurses'voice behavior is upper medium with heterogeneity,which can be divided into 3 latent profiles.Nurses managers should focus on nurses with conservation group and balanced-risky group and conduct early targeted prevention and care according to characteristics and influencing factors of different latent profile.

Influencing factors and nursing enlightenment of the fear of progression in patients with inflammatory bowel disease:a latent profile analysis / 中华护理杂志

Objective To explore the potential categories and influencing factors of the fear of progression in patients with inflammatory bowel diseases(IBD).Methods IBD patients who received inpatient treatment in a tertiary hospital in Nanjing from July 2022 to July 2023 were selected as the study subjects by convenience sampling method.The General Demographic Information Questionnaire,the Chinese version of the Fear of Progression Questionnaire-Short Form(FoP-Q-SF),the Chinese version of Inflammatory Bowel Disease Self-efficacy Scale(IBD-SES),and Social Support Rating Scale(SSRS)were administered to the participants.We applied one-way ANOVA and Logistic regression analysis to identify the factors associated with the potential categories of the fear of progression.Results A total of 303 retumed questionnaires(out of the 310)were valid,resulting an effective response rate of 97.74％.According to the results of latent profile analysis,we classified the respondents into 3 categories by the fear of progression,namely"low risk fear of disease adaptation group"(n=127,41.91％),"medium risk fear of illness distress group"(n=139,45.88％),"high risk fear of dysfunction group"(n=37,12.21％).3 groups showed statistically significant differences in permanent address,self-rated financial pressure,current disease status and self-efficacy(P＜0.05).Conclusion Patients with IBD had obvious differences in characteristics on the fear of progression.Nursing personnel should formulate personalized intervention strategies based on the classification characteristics of the fear of progression of IBD patients.Moreover,nurses should focus on improving patients'self-efficacy and promoting patients to treat medical care,stress and emotion management correctly.

Classification and influencing factors of family resilience and post-traumatic growth in spinal tumor patients based on potential profile analysis / 中华全科医师杂志

Objective:To explore the classification and influencing factors of family resilience and post-traumatic growth in patients with spinal tumor.Methods:A cross-sectional investigation was conducted among 219 inpatients with spinal tumor admitted from July 2021 to July 2022. The General Demographic Information questionnaire, Chinese-Family Resilience Assessment Scale, Posttraumatic Growth Inventory, Family Crisis-Oriented Personal Evaluation Scales (F-COPES), and Social Support Rating Scale (SSRS) were used in the study. The ordinal and multivariate logistic regression analyses was applied to identify the factors associated with the classification of family resilience and post-traumatic growth.Results:Of the 219 patients, there were 62 cases of primary spinal tumors (28.3%). According to the results of latent profile analysis, the respondents were classified into three categories by family resilience and post-traumatic growth, namely family difficulty-resistant type ( n=38, 17.4%), general resilience-struggle type ( n=99, 45.2%) and family adaptation-growth type ( n=82, 37.4%). There were significant differences in occupational status, commitment to housework, family atmosphere( χ2=10.75, P=0.025; χ2=6.95, P=0.031; χ2=11.37, P=0.017), and total score of F-COPES and SSRS ( F=25.95, P<0.001; F=19.06, P<0.001)among three groups. Ordinal and multivariate logisitc regression analyses showed that retirement ( OR=2.928, 95% CI:1.098-7.808, P<0.05), family coping ( OR=1.113, 95% CI:1.063-1.165, P<0.05), and social support ( OR=1.226, 95% CI:1.103-1.362, P<0.05) were independently associated with family resilience and post-traumatic growth in patients with spinal tumor. Conclusion:Patients with spinal tumor have significant differences in characteristics by family resilience and post-traumatic growth. As a result, more targeted interventions should be provided for different categories of spinal tumor patients in the future.

Effects of gestational diabetes mellitus on brain development and miRNAs expression profile in neonatal mice / 中国儿童保健杂志

【Objective】 To study the effects of gestational diabetes (GDM) on morphological structure of brain tissue and microribonucleotide (miRNA) expression profile in neonatal mice, and to provide a new research target for the prevention and treatment of abnormal neurodevelopment in GDM progeny. 【Methods】 The pregnant mice were divided into model group and control group,each group consisted of 10 mice. The model group mice established a GDM model by injecting streptozotocin to measure fasting blood glucose (FPG) and random blood glucose (GLU) at different times. Successful molded mice were randomly divided into model group A and model group C, and control mice were divided into control group B and control group D, with 5 mice in each group. The newborn mice in groups A and B were used for hippocampal tissue GeneChip detection and brain morphology structure observation, and group C and D newborn mice were used for qRT-PCR detection of hippocampus tissue expression differences to verify the differentially expressed genes of miRANs obtained by GeneChip screening. After giving birth, the neonatal mice were sacrificed by decapitation, and the brain tissue was dissected to observe the overall morphological structure. The structural changes of hippocampus were observed under HE chromogenic microscope. The Agilent mouse miRNA oligonucleotide gene chip was used to detect the miRNA expression profile of mouse hippocampus, screen differential miRNAs and predict their target genes, and conduct GO analysis and signal transduction pathway analysis of target genes. The relative expression levels of the screened miRNAs were verified by qRT-PCR. 【Results】 Compared with the control group, the GLU increased significantly from the 3rd day after drug administration in the model group (P<0.01). Macroscopic observation of control group B mice had normal brain morphology and structure, smooth appearance, clear gyrus, close arrangement of hippocampus cell structure, uniform staining and complete structure; in model group A, the number of hippocampus cells decreased, loose arrangement and deep staining. In the initial screen of miRNA microarray, there were 11 differentially expressed miRNAs between control and model groups, all of which were downregulated miRNAs, including let-7b-5p、miR-130b-3p、miR-181c-5p、miR-181d-5p、miR-3099-3p、miR-3470a、miR-3473a、miR-3473b、miR-500-3p、miR-532-5p、miR-7047-5p(P<0.05). Two miRNAs (miR-3473b, miR-7047-75p) and 5 target genes (MAPK3, MAPK11, MAPK14, CALM3, AKT3). The relative expression of miR-3473b and miR-7047-5p in model group C were lower than that in control group D (t=19.13 and 6.24, P<0.05), and the validation results were consistent with the microarray test results. 【Conclusion】 Compared with the offspring of normal pregnant mice, GDM offspring mice have abnormal development of brain structure and damage of hippocampal nerve cells, and there are a large number of abnormal expression of miRNAs in hippocampal tissue. Differentially expressed miRNAs can be used as research targets for prevention and treatment of GDM offspring neurodevelopmental abnormalities.

Effects of combination of curcumin and piperine supplementation on glycemic profile in patients with prediabetes and type 2 diabetes mellitus: A systematic review and meta-analysis / Journal of the ASEAN Federation of Endocrine Societies

Objective@#This study aimed to evaluate the effects of combination of curcumin and piperine supplementation on Fasting Plasma Glucose (FPG), Homeostatic Model of Insulin Resistance (HOMA-IR), Body Mass Index (BMI) in patients with prediabetes and type 2 Diabetes Mellitus (T2DM). This review was done to identify potential herbal remedies that may help improve glycemic parameters, leading to better health outcomes in combination with current antidiabetic treatment.@*Methodology@#This systematic review was based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). It was conducted in 2023 with sources and databases from MEDLINE, EBSCO-Host, ScienceDirect and ProQuest. This paper included randomized-controlled trials exploring the effects of the combination of curcumin and piperine on patients with prediabetes and T2DM. Systematic reviews, observational studies, case reports, case series, conference abstracts, book sections, commentaries/editorials, non-human studies and articles with unavailable full-text and written in non-English language, were excluded. The key terms for the literature search were “curcumin,” “piperine,” “prediabetes” and “Type 2 Diabetes Mellitus.” We use Cochrane Risk of Bias (RoB) 2 for quality assessment of the included studies and Review Manager (RevMan) 5.4 to do the meta-analysis.@*Results@#A total of three studies were included in this systematic review. Two studies from Neta et al., and Cicero et al., showed no significant difference in HOMA-IR, BMI and FPG levels between the curcumin, piperine and placebo groups. One study from Panahi et al. demonstrated a significant difference in BMI levels between the curcumin and piperine and placebo groups (p <0.01). The meta-analysis showed that FPG levels, HOMA-IR and BMI improved among patients with diabetes given in curcumin and piperine with reported mean differences (MD) of = -7.61, 95% CI [-15.26, 0.03], p = 0.05, MD = -0.36, 95% CI [-0.77 to 0.05], p = 0.09, and MD = -0.41, 95% CI [-0.85 to 0.03], p = 0.07, respectively).@*Conclusions@#The supplementation of curcumin and piperine showed a numerical reduction in FPG, HOMA-IR and BMI, but were not statistically significant. Further research is needed as there is a paucity of studies included in the review.

A retrospective study of micro-implant anchorage in the upper posterior region to improve gummy smiles / 口腔疾病防治

Objective@#To analyze the ability of micro-implant nails placed in different locations in the posterior region to improve the hard and soft tissues of the labiodental region in patients with gummy smiles to provide a reference for clinicians.@*Methods@#This study was reviewed and approved by the Ethics Committee, and informed consent was obtained from the patients. Thirty young female patients with anterior tooth protrusions and gummy smiles were included in the retrospective study; 18 patients had micro-implant nails implanted between the premolars (group A), and 12 patients had implant nails placed between the roots of the premolar and the molar and an intraoperatively placed rocking-chair archwire (group B). The preoperative and postoperative distances from the incisal end of the upper mesial incisors to the lower point of the upper lip (U1-Stms), the vertical distance from the incisal end of the upper mesial incisors to the palatal plane (U1-PP), the vertical distance from the point of the alveolar ridge to the palatal plane (Spr-PP), the distance from the incisal end of the upper mesial incisors to the point of the alveolar margin (U1-Spr), and the vertical distance from the point of the proximal middle buccal cusp of the maxillary first molar to the palatal plane of the maxillary first molar (U6-PP) were measured in the cephalometric lateral radiographs of the two groups; additionally, the amount of hard and soft tissues of the upper anterior region exposedduring smiling and the maximum amount of gingiva exposed during smiling were assessed from the smile photograph.@*Results@#After correction, the lip-dentition relationship improved significantly in both groups, with an average reduction of 2.6 mm in U1-Stms, 2.4 mm in U1-PP, 1.4 mm in Spr-PP, and 0.9 mm in U1-Spr in Group A. In group B, the U1-Stms was reduced by an average of 2.3 mm, the U1-PPs by an average of 1.6 mm, the Spr-PPs by 1.4 mm, and the U1-Spr by 0.2 mm. The difference between pre- and postoperative U6-PP in both groups was not significant (P>0.05). Group A had greater ∆U1-PP and ∆U1-Spr changes than group B(P<0.05). There was no difference between the two groups in terms of ∆U1-Stms or ∆Spr-PP (P>0.05). The amount of soft and hard tissue exposed and maximum amount of gingiva exposed in the upper anterior region of the smile were reduced in 30 patients postoperatively, with group A having anaverage reduction of 70.19% of the preoperative amount of soft and hard tissue exposed in the upper anterior region and an average reduction of 24.12% of the preoperative maximum amount of gingiva exposed, and group B having an average reduction of 76.12% of the preoperative amount of hard and soft tissue exposed in the upper anterior region and an average reduction of 31.88% of the preoperative maximum gingiva exposed after the operation. The difference in the ratio between the two groups was not statistically significant (P>0.05).@*Conclusion@#For patients with proptosis and gummy smiles, placing micro-implant nails between the roots of maxillary premolars can effectively lead to retraction and intrusion of anterior teeth to improve the lip-dentition relationship and improve gummy smile, and placing micro-implant nails between the roots of the maxillary second premolar and the first molar together with the use of rocking chair arches can also achieve a good therapeutic effect.