RÉSUMÉ
Objective To analyze the influence of patients with multiple cerebral infarction complicated with vascular Parkinsonism (VaP) on cognitive function, and to provide a theoretical basis for the diagnosis and treatment of patients with multiple cerebral infarction complicated with VaP. Methods A toatl of 206 patients with multiple cerebral infarction admitted to Ningde municipal hospital of ningde normal university from January 2020 to January 2022 were selected and divided into VaP group (n=58) and control group (n=148) according to whether they were complicated with VaP. Montreal Cognitive Assessment Scale (MoCA) was used to evaluate the cognitive function of patients. The scale included 8 cognitive domains including attention and concentration, executive function, memory, language, visual structure skills, abstract thinking, calculation and orientation. Pearson was used to analyze the correlation between VaP and MoCA score in patients with multiple cerebral infarction. Age, sex, years of education, white matter disease, diabetes mellitus, coronary heart disease and other vascular risk factors were compared between the two groups. The independent risk factors for VaP in multiple cerebral infarction were analyzed by multiple linear regression. Results MoCA score in VaP group was significantly lower than that in control group (P<0.05). In terms of each item, scores of attention and concentration, memory, language and computation in VaP group were significantly lower than those in control group (P<0.05). Pearson correlation analysis showed that attention and concentration, memory, language and computational scores were correlated with VaP in patients with multiple cerebral infarction (r=-0.475, -0.314 , -0.302 , -0.389, P<0.05). There were statistically significant differences between the two groups in white matter lesions, lesion sites in left hemisphere and frontal lobe, diabetes mellitus and carotid artery plaque (P<0.05).White matter lesions (OR=2.571), diabetes mellitus (OR=2.369) and lesion location in the left hemisphere (OR=2.958) were independent risk factors for VaP in patients with multiple cerebral infarction (P<0.05). Conclusion The risk of VaP in multiple cerebral infarction is high, which is related to the cognitive function of patients. Early intervention such as brain function training should be given to patients with white matter lesions, diabetes and lesions in the left hemisphere. , can significantly improve patients' cognitive function and reduce the occurrence of VaP.
RÉSUMÉ
Este estudo teve como objetivo caracterizar uma população idosa asilar com síndrome parkinsoniana quanto a forca muscular respiratória, nível cognitivo e independência nas atividades de vida diária. O estudo caracterizou-se como uma serie de casos prospectivos, na qual a amostra foi constituída por sete idosas diagnosticadas com síndrome parkinsoniana. O estado cognitivo das participantes foi avaliado por meio do Mini-Exame de Estado Mental, a capacidade funcional pelo Índice de Katz e a forca muscular respiratória (inspiratória e expiratória) por manovacuometria. Os resultados deste estudo demonstraram que, em relação ao nível cognitivo, 71,44% das idosas apresentaram perda cognitiva moderada; na capacidade funcional, a maioria apresentou independência parcial (57,14%) e a forca muscular respiratória se apresentou abaixo do esperado. Através dos resultados, foi possível concluir que, alem do próprio envelhecimento, a SP pode ter influenciado de maneira negativa os aspectos cognitivos, a forca muscular respiratória e a capacidade funcional das idosas avaliadas.
This study aim was to characterize an asylum elderly population with Parkinsonian Syndrome regarding their respiratory muscle strength, cognitive level and independence in activities of daily living. The study was characterized as a series of prospective cases, in which the sample was composed of seven elderly women diagnosed with Parkinsonian Syndrome. The cognitive status of the participants was assessed through the Mini-Mental State Examination, the functional capacity by the Katz Index and the respiratory muscle strength (inspiratory and expiratory) by manovacuometry. The results of this study showed that in relation to the cognitive level, 71.44% of the elderly had mild cognitive impairment; in functional capacity, the majority showed partial independence (57.14%) and the respiratory muscle strength performed below expectations. Through the results, one might conclude that, in addition to aging itself, the PS may have influenced negatively the cognitive aspects, the respiratory muscle strength and the functional capacity of the assessed elderly.