Résumé
Introduction: Use of In-vitro fertilization (IVF) has raisedmajor concern about the outcome of resulting pregnancies. InVitro Fertilization and Embryo Transfer is the most advancedtechnique of infertility treatment though management of thesepregnancies is not that easy as the couples and treating doctorshave undue concerns and apprehensions about the outcomesof such pregnancies.Material and Methods: Obstetrics outcomes in the womenconceived through IVF and the neonatal characteristics of thelive- born infants at Army Hospital R & R were analyzed inthis study between Jan 2017 to Dec 2017.Results: IVF pregnancies increased the incidence of ectopicpregnancy and multifetal gestation. The rate of cesareansection was also higher in IVF pregnancies. While a largenumber of cases delivered vaginally, multiple pregnancies andpreterm labour were more frequent in the study group. Afterfirst trimester they can be managed as a normal pregnancy.Conclusion: Infertility cases are usually older, and this isone of the reasons for increased complications in pregnancy.Multiple pregnancies are the most prevalent complicationin these pregnancies. Risk of ectopic pregnancy has beenreported to be at least 2-fold higher in In-vitro fertilizationand Embryo- Transfer (IVF-ET) pregnancies.
Résumé
Although Plasmodium vivax is the major species responsible for malaria in most parts of India, P. falciparum infections have now increasingly been reported from some parts of India. A study was therefore, undertaken to compare immuno-chromatographic technique (ICT) based Malaria card test with microscopic examination of peripheral blood film in diagnosis of malaria in and around Loni, Maharashtra. A total of 143 (about 24%) samples of 590 febrile patients tested were detected positive for malarial infection- 74 samples for P. vivax (approx. 52%) and 69 for P. falciparum (approx. 48%). With Malaria card test, the sensitivity and specificity of 93.8% and 92.6% were recorded for P. vivax and 95.2% and 95.5% for P. falciparum, respectively. Therefore, the test is a valuable adjunct in an emergency for rapid diagnosis of malaria, though microscopy remains the mainstay for routine use in countries, like India.
Résumé
Background: Vitamin E works within the cell membrane as an antioxidant and may prevent destruction of RBC in G6PD deficient hemolytic anemia, which can be reflected by changes in peripheral blood film. Objective: To observe the role of vitamin E supplementation on restoring normal cell types in peripheral blood film in order to evaluate the role of this antioxidant vitamin in reducing chronic hemolysis in G6PD deficient patients. Method: Total 102 subjects, age range from 5-40 years of both sexes were included in the study. Among them 68 were G6PD enzyme deficient patients, of whom 34 were in non-supplemented group (Group B) and 34 were in supplemented group (Group C). Both group B and C were divided into Group B1 and C1 (on day 1 ) and also into B2 and C2 (on day 60) respectively. Supplemented group received vitamin E supplementation for 60 consecutive days (800 IU/day for adult and 400 IU/day for children in a divided dose i,e. 4 times daily). Age and sex matched 34 apparently healthy subjects with normal G6PD level (Group A) were also taken to observe baseline data. Determination of Erythrocyte G6PD level and preparation of peripheral blood film were done on day 1 for all groups and also on day 60 in deficient groups. Results: Percentage of subjects with presence of some abnormal red cells in peripheral blood film was significantly higher in patients of hemolytic anemia with G6PD deficiency in comparison to that of healthy control. After supplementation with vitamin E (i,e. on day-60) this percentage was significantly decreased towards those of healthy control in their supplemented group in comparison to that of pre-supplemented (day-1) and nonsupplemented groups. Conclusion: Some abnormal red cells may be found in peripheral blood film of G6PD deficient patients, improvement of which occur following vitamin E supplementation, and thereby indicates role of this antioxidant vitamin in reducing the rate of hemolysis.