Phyllode an Uncommon Tumor of the Breast - A Case Report

‘Phyllodes’ is a Greek word which means leaf- like. Phyllodes tumour, though appears well circumscribed, is characterized by irregular surface surface projections. These projections may be cut during surgical excision and predispose to recurrence. Phyllodes tumour shows a wide spectrum of activity varying from an almost benign condition to a locally aggressive, and sometime metastatic tumour. We report a 61 year old female patient presented with a lump on the left breast. Excision was done and histo pathology report revealed phyllode tumour.

Histomorphological spectrum of Phyllodes Tumours: A Restrospective Study

Introduction: Phyllodes tumours are rare fibroepithelial lesions of breast. Clinical examina?on, ultrasound, cytology and histopathology are the mainstay of the diagnosis. The present research was undertaken with the aim of studying the clinicopathological features of Phyllodes tumour reported in the past seven years in a Delhi government hospital. Method: A retrospec?ve study of phyllodes tumour was carried out in females from 225 diagnosed cases of breast lesion reported in the pathology department of a government hospital in Delhi during the period of January 2013 to December2019. All the relevant history, findings of clinical examina?on and inves?ga?ons performed were assessed from files of the pa?ent. Results: Out of 225 cases of breast lesions reported in the pathology department 8 tumours were reported as phyllodes in the study period. The most common affected age group was 41- 50yrs. 5 (62.5 %) of 8 tumours were benign,2 (25) %) were borderline and only 1 was malignant. The tumour size was 15mm to 200mm. All the 8 cases (100%) presented with breast lump; 3 cases (30%) complained of pain in the lump. 2 cases developed ulcera?on and Peau D’ orange and in 1 case typical nipple retrac?on was seen. FNAC was done in 5 pa?ents. No preopera?ve inves?ga?ons were done in 2cases. Conclusion: Phyllodes tumour is a rare neoplasm of the breast. Histopathology plays an important role in differen?a?ng it from fibroadenoma. Strict histologic assessment is definitely required for the diagnosis of the PT and for its treatment and management

Study of Histomorphological Spectrum of Benign Breast Diseases in a Tertiary Care Centre of Mumbai

Breast, a modified sweat gland exhibits a wide spectrum of pathological lesions, usually presenting as palpable masses ranging from inflammatory to neoplastic lesions. Neoplastic lesions can be either benign or malignant. These lumps are always a cause of anxiety to the patients and their family members.1 Breast diseases are showing a rising trend worldwide. A number of studies have been done in order to know the magnitude of the problem. The present study was undertaken with an aim to determine the incidence and the histopathological spectrum of various benign breast lesions at our institute.METHODSThe present study of the breast lesions was performed in the department of pathology in a general teaching hospital and tertiary referral health care centre in Mumbai. The information and data from clinical records was collected and analysed.RESULTSA total of 953 cases of breast lesions was studied and analyzed over a period of 10 years and 10 months. Of the total 953 cases, 653 (68%) cases were benign lesions. Fibroadenoma (63%) was the commonest lesion followed by inflammatory lesions (12%) and benign phyllodes tumour (5.7%).CONCLUSIONSThe term “benign breast diseases” encompasses a heterogeneous group of lesions that may present with a wide range of symptoms or may be detected as incidental microscopic findings, and these are more frequent lesions of breast than malignant ones. Histopathological study plays important role to reach the correct diagnosis in certain benign breast diseases which mimic cancers clinically. Present study is in concordance with other studies showing fibroadenoma as commonest benign breast lesion.

Breast Necrosis: A Rare Case of Neglected Phyllodes Tumour

@#Phyllodes tumour (PT) of the breast is firstly described in literature as early as 1838. This article reports the youngest recorded case of giant complicated PT and the role of toilet mastectomy as a salvage surgery. A 19-year-old lady presented with a gigantic lump of the left breast for 6 months which was rapidly growing (20 x 20 cm) and complicated with a foul-smelling blackish discoloration of the breast skin and tissues. Toilet mastectomy was performed as a result. The specimen weighed 4.0 kg with histopathological report of the tumor being borderline phyllodes. Herein, we describe a case of PT, who presented with breast necrosis and we discuss its medico-social aspect of it.

Case Report: Massive Ruptured Malignant Phyllodes Tumour

Phyllodes tumour is a rare entity, affecting mainly middle aged women. It consists of a spectrum of disease from benign tumour to highly aggressive malignant form. We present a case of massive ruptured malignant Phyllodes tumour, and its subsequent management.

Tumor filoide. Estado del arte / Phyllodes tumour. State of the art

El tumor filoide (TF) es una neoplasia fibroepitelial con una baja incidencia a nivel mundial, lo que limita el poder contar con estudios prospectivos acerca de su abordaje diagnóstico y terapéutico. Se hace una revisión actualizada de su presentación, diagnóstico y tratamiento. Con las características histopatológicas disponibles actualmente se puede subdividir el TF en: de histología benigna, limítrofe y maligna. Esta subclasificación permite establecer el abordaje quirúrgico, que es la base del manejo terapéutico, la indicación de terapias adyuvantes, y finalmente establecer el pronóstico de la paciente.

Phyllodes tumour is a fibroepithelial neoplasm of the breast, with a low world incidence, and with few prospective trials on its diagnosis and treatment. A review is presented of the available world medical literature on this topic. Phyllodes tumours can currently be classified as benign, borderline and malign. This classification helps to determine the surgical treatment, which is the cornerstone of the treatment of Phyllodes tumour, as well as the adjuvant treatment, and finally it helps to determine the patient's prognosis.

Phyllodes tumours of the breast: retrospective analysis of a University Hospital’s experience

Taking cognizance of the purported variation of phyllodes tumours in Asians compared with Western populations, this study looked at phyllodes tumours of the breast diagnosed at the Department of Pathology, University of Malaya Medical Centre over an 8-year period with regards to patient profiles, tumour parameters, treatment offered and outcome. Sixty-four new cases of phyllodes tumour were diagnosed during the period, however only 30 (21 benign, 4 borderline and 5 malignant) finally qualified for entry into the study. These were followed-up for 4-102 months (average = 41.7 months). Thirteen cases (8 benign, 3 borderline, 2 malignant) were Chinese, 9 (all benign) Malay, 7 (4 benign, 1 borderline, 2 malignant) Indian and 1 (malignant) Indonesian. Prevalence of benign versus combined borderline and malignant phyllodes showed a marginally significant difference (p=0.049) between the Malays and Chinese. Patients’ ages ranged from 21-70 years with a mean of 44.9 years with no significant difference in age between benign, borderline or malignant phyllodes tumours. Except for benign phyllodes tumours (mean size = 5.8 cm) being significantly smaller at presentation compared with borderline (mean size = 12.5 cm) and malignant (mean size = 15.8 cm) (p<0.05) tumours, history of previous pregnancy, breast feeding, hormonal contraception and tumour laterality did not differ between the three categories. Family history of breast cancer was noted in 2 cases of benign phyllodes. Local excision was performed in 17 benign, 2 borderline and 3 malignant tumours and mastectomy in 4 benign, 2 borderline and 2 malignant tumours. Surgical clearance was not properly recorded in 10 benign phyllodes tumours. Six benign and all 4 borderline and 5 malignant tumours had clearances of <10 mm. Two benign tumours recurred locally at 15 and 49 months after local excision, however information regarding surgical clearance was not available in both cases. One patient with a malignant tumour developed a radiologically-diagnosed lung nodule 26 months after mastectomy, was given a course of radiotherapy and remained well 8-months following identification of the lung nodule.

Surgical treatment of phyllodes tumour of the breast in Siriraj Hospital.

The authors studied retrospectively the surgical treatment of phyllodes tumour of the breast patients between 1989-1994 in the Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University. 24 patients were found. Their ages ranged from 18-60 years (mean 40 years). 17 patients were single and 7 patients were married. The pathological diagnoses of the growths were 15 benigns, 6 borderline malignants and 3 malignants. The size clinically were 1.5 to 30 cm (mean 10.7 cm.) and pathologically were 2 to 48 cm. (mean 10.98 cm.). 7 patients (29.17%) suffered recurrence of the growths. The time that the breast masses were detected before coming to the hospital ranged from 1 to 36 months (mean 7 months). The follow-up period ranged from 4 to 71 months (mean 17 months). The latest surgical procedures were 12 excisions, 7 simple mastectomies 2 subcutaneous mastectomies, 2 modified radical mastectomies, and 1 extended radical mastectomy.