Solitary Plasmacytoma of Mandible – A Rare Dyscrasia- Case Report and Review of Literature

Introduction: The plasma cell neoplasms may present in soft tissue as extramedullary plasmacytomas, bone as a solitary plas- macytoma of bone, or as part of the multifocal disseminated disease multiple myeloma. Aim of study: The study aims to report solitary plasmacytoma in the gnatic bone oral cavity, which is also mimicking as malig- nant neoplasm of bone, seen in a female patient. Case Report: A 38-year-old female patient reported to the outpatient department of our hospital complaining of pain and swelling over the left lower one-third region of the face for one month CBCT analysis shows a hypodense area involving 35 regions extending towards ascending rami of the mandible. Conclusion: Plasmacytoma, despite being a lesion with slow, asymptomatic growth, can assume large volumes, making proper treatment difficult. When there is no bone involvement and it is diagnosed early, the success of treatment is generally higher. The treatment of choice is radiotherapy, with good results for the remission of the lesion

Plasmacytoma in the oral cavity: a case report / Plasmocitoma en la cavidad oral: reporte de caso

The plasma cell neoplasms may present in soft tissue as extramedullary plasmacytoma (EMP), in bone as a solitary plasmacytoma of bone (SPB), or as part of the multifocal disseminated disease multiple myeloma (MM). The EMP is rare, comprising around 3 percent of all plasma cell neoplasm. The majority (80 percent) occurs in the head and neck region. In this study we report a case of a man, 70 years old, melanoderm, with a lesion of the oral cavity. Upon physical examination, a lesion was found that extended throughout the posterior upper alveolar ridge, as far as the maxillary tuber on the left side, extending towards the palate. Radiographic examination, complementary laboratory exams were performed. Based on the conclusive symptoms of plasmacytoma, the patient was referred to the hematology service for treatment with local radiotherapy. The patient responded satisfactorily to the treatment, and after 15 months, all clinical symptoms of the lesion in the oral cavity had disappeared.

La neoplasia de células plasmáticas se presenta en los tejidos blandos como plasmocitoma extramedular (EMP), en el hueso como plasmocitoma solitario (SPB), o como parte de una enfermedad diseminada, el mieloma múltiple (MM). El EMP es poco frecuente, manifestandose en alrededor de un 3 por ciento. Se presentan generalmente (80 por ciento) en las regiones de cabeza y cuello. En este reporte de caso, un hombre de 70 años, melanoderma, presentaba una lesion en la cavidad oral. En el examen físico se observó la lesión a lo largo de la parte posterior del reborde alveolar superior, en la tuberosidad maxilar en el lado izquierdo hacia el paladar. Se realizaron exámenes radiográficos y de laboratorio. Con base en los signos de plasmocitoma, el paciente fue referido a tratamiento con radioterapia. El tratamiento fue muy exitoso y después de 15 meses se observó que el paciente no presentaba los signos clínicos característicos de la lesión neoplásica.