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Arch. endocrinol. metab. (Online) ; 60(1): 5-8, Feb. 2016. tab
Article Dans Anglais | LILACS | ID: lil-774621

Résumé

ABSTRACT Objective This prospective study evaluated the recurrence rate in low-risk patients with papillary thyroid cancer (PTC) who presented slightly elevated thyroglobulin (Tg) after thyroidectomy and who did not undergo ablation with131I. Subjects and methods The study included 53 low-risk patients (nonaggressive histology; pT1b-3, cN0pNx, M0) with slightly elevated Tg after thyroidectomy (> 1 ng/mL, but ≤ 5 ng/mL after levothyroxine withdrawal or ≤ 2 ng/mL after recombinant human TSH). Results The time of follow-up ranged from 36 to 96 months. Lymph node metastases were detected in only one patient (1.9%). Fifty-two patients continued to present negative neck ultrasound. None of these patients without apparent disease presented an increase in Tg. Conclusions Low-risk patients with PTC who present slightly elevated Tg after thyroidectomy do not require ablation with 131I.


Sujets)
Adolescent , Adulte , Sujet âgé , Sujet âgé de 80 ans ou plus , Femelle , Humains , Mâle , Adulte d'âge moyen , Jeune adulte , Carcinomes/thérapie , Radio-isotopes de l'iode/usage thérapeutique , Récidive tumorale locale , Thyroïdectomie , Thyroglobuline/sang , Tumeurs de la thyroïde/thérapie , Carcinomes/sang , Carcinomes/anatomopathologie , Études de suivi , Métastase lymphatique , Études prospectives , Tumeurs de la thyroïde/sang , Tumeurs de la thyroïde/anatomopathologie , Thyrotropine alfa/usage thérapeutique
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