Comparative Study of Oscillation of Pulmonary Artery Pressure to That of Systemic Artery Pressure

PURPOSE: The purpose of this study is to examine the difference between the below respiratory-frequency oscillations of the pulmonary artery pressure and those of the systemic arterial pressure. METHODS: The subjects in this experiment were patients suffering from ventricular septal defect and having treatment with the cardiac catheterization at Gyeongsang National University Hospital. Signals from pulmonary artery pressure, femoral artery pressure and the respiration of the patients were received for 5 minutes and digitalized and stored into the personal computer. Those data were interpreted and compared by the power spectral analysis method. RESULTS: 1) In case that the mean pulmonary artery pressure was below 30mmHg(n=23), the low frequency, the mid frequency, the respiratory frequency and the total frequency power of the pulmonary artery pressure were 4.17+/-0.65(3.15-5.40), 3.81+/-0.66(2.79-4.96), 6.06+/-0.27(5.57-6.83) and 6.78+/-0.34(6.01-7.36) respectively. And the those of the femoral artery pressure were 5.24+/-0.49(4.46-6.13), 4.27+/-0.57(3.34-5.45), 5.54+/-0.44(4.72-6.13) and 7.44+/-0.51(6.07-7.94). So in all the frequency ranges a significant difference was observed between the pulmonary artery pressure and the systemic blood pressure(p30mmHg), the low frequency oscillation of the pulmonary artery pressure and the respiratory frequency oscillation of the systemic blood pressure were increased, resulting in the same oscillation in the low frequency, the mid frequency, the respiratory frequency and the total frequency. CONCLUSIONS: The magnitude of ossillation of pulmonary artery pressure was very similar to the magnitude of ossilation of systemic arterial pressure in the below-respiratory-frequency when pulmonary artery pressure was high(>30mmHg).

Comparative Study of Oscillation of Pulmonary Artery Pressure to That of Systemic Artery Pressure

PURPOSE: The purpose of this study is to examine the difference between the below respiratory-frequency oscillations of the pulmonary artery pressure and those of the systemic arterial pressure. METHODS: The subjects in this experiment were patients suffering from ventricular septal defect and having treatment with the cardiac catheterization at Gyeongsang National University Hospital. Signals from pulmonary artery pressure, femoral artery pressure and the respiration of the patients were received for 5 minutes and digitalized and stored into the personal computer. Those data were interpreted and compared by the power spectral analysis method. RESULTS: 1) In case that the mean pulmonary artery pressure was below 30mmHg(n=23), the low frequency, the mid frequency, the respiratory frequency and the total frequency power of the pulmonary artery pressure were 4.17+/-0.65(3.15-5.40), 3.81+/-0.66(2.79-4.96), 6.06+/-0.27(5.57-6.83) and 6.78+/-0.34(6.01-7.36) respectively. And the those of the femoral artery pressure were 5.24+/-0.49(4.46-6.13), 4.27+/-0.57(3.34-5.45), 5.54+/-0.44(4.72-6.13) and 7.44+/-0.51(6.07-7.94). So in all the frequency ranges a significant difference was observed between the pulmonary artery pressure and the systemic blood pressure(p30mmHg), the low frequency oscillation of the pulmonary artery pressure and the respiratory frequency oscillation of the systemic blood pressure were increased, resulting in the same oscillation in the low frequency, the mid frequency, the respiratory frequency and the total frequency. CONCLUSIONS: The magnitude of ossillation of pulmonary artery pressure was very similar to the magnitude of ossilation of systemic arterial pressure in the below-respiratory-frequency when pulmonary artery pressure was high(>30mmHg).

The Novel Low Frequency Oscillation in Pulmonary Artery Pressure

BACKGROUND: It is well known that systemic blood pressure oscillates with low(0.04~0.1Hz), mid(0.1~0.15Hz), and high(respiratory) frequency range. But there has been no study about oscillation of pulmonary artery pressure(PAP). METHOD: We measured PAP for 5 minutes in 32 patients of ventricular septal defect and stored them to computer files. Power spectral density curve was obtained. Low, mid, respiratory frequency power were measured by integrating the area within each frequency range below the power density curve. RESULT: The incidence of significant low frequency power(more than 5% of total power) were higher in patients of high PAP and hign Rp/Rs than those of low PAP and Rp/Rs(p<0.01 and p<0.005 respectively). The low frequency power positively correlates with PAP and Rp/Rs(r=0.62, p<0.0005 and r=0.61, p=0.0005 respectively). CONCLUSION: It can be said conclusively that as PAP and pulmonary vascular resistance elevates, the PAP tends to definitively oscillate in low frequency range.