Clinical significance of Qmax and residual urine in benign prostatic hyperplasia / 中华泌尿外科杂志

Objective To investigate the significance of Qmax and residual urine in evaluation of bladder function in the patients with benign prostatic hyperplasia (BPH).Methods The clinical data of 61 patients with BPH and 20 healthy persons in control group were evaluated.Bladder function,uroflowmetry and ultrasonic residual urine measurement were performed in the 2 groups.The correlation between Q max and residual urine in BPH group was investigated.Results There was significant difference in Qmax between the BPH group and control group (8 vs.21 ml/s,u=-6.090,P=0.007).There was significant difference in residual urine between the 2 groups (60 vs.9 ml,u =-6.718,P=0.005).And there was a negtive correlation between residual urine and Qmax in BPH group (r=-0.366,P=0.009).Conclusion It is useful to measure the Qmax and residual urine in evaluation of bladder function affected by bladder outlet obstruction caused by BPH.

Terazosin treatment in BPH/LUTS: a prospective, randomized, multicenter study / 中华泌尿外科杂志

Objective To compare the efficacy and safety of 2 mg/d and 4 mg/d of terazosin in the treatment of benign prostatic hyperplasia (BPH) with lower urinary tract symptoms (LUTS).Methods A total of 120 BPH patients were randomly divided into 2 groups receiving 2 mg or 4 mg terazosin per day for 2 months. Arterial blood pressure, International Prostatic Symptom Score (IPSS) and peak flow rate (Qmax) before and after treatment were compared while side effects were estimated. Results Forty-six patients receiving 2 mg and 54 patients receiving 4 mg terazosin completed this study. Patients' age and pre-treatment blood pressure, IPSS and Qmax had no difference between the 2 groups. The improvement of IPSS (including obstructive score, irritating score and total IPSS) and Qmax was significantly better in 4 mg group. The percentage of patients experiencing greater than 30% improvement in Qmax in the 4 mg treatment groups was significantly higher than that of the 2 mg group (46.3% vs 23.9%, P=0.02). Side effects were rare and mild in both groups.Conclusion The improvements of IPSS and Qmax are significantly greater in 4 mg treatment of terazosin than that of 2 mg with no obvious increase of side effects.

Analysis of Lower Urinary Tract Symptoms Associated with Prostate Findings in Occupational Taxi Drivers and Office Workers in Uijeongbu, Korea

PUROPOSE: To analyze lower urinary tract symptoms associated with prostate findings in occupational taxi drivers compared to office workers in Uijeongbu, Korea. MATERIAL AND METHODS: A population-based cross-sectional survey was conducted among drivers and office workers in Uijeongbu, Korea. All participants filled out the International Prostate Symptom Score (IPSS) questionnaire and the age, career, height and body weight were also recorded. They had uroflowmetry (UFM), transrectal ultrasound (TRUS) and prostatic cancer screening testing (PSA). We evaluated the parameters and compared them between the two groups. RESULTS: There was no significant difference in age, career and BMI between the two groups (p<0.01). For each group, the IPSS was closely related to the maximal flow rate (Qmax) (p<0.01). The mean value of the IPSS was 13.53+/-7.70 in the taxi drivers and 9.71+/-5.72 in office workers; therefore, the IPSSs showed a difference between the two groups (p=0.041). However, there were no significant differences among the other parameters between two groups. The value of Qmax was not significantly different in the comparisons between the two groups (p=0.973). CONCLUSIONS: Although the IPSS in taxi drivers was higher than in office workers, the objective parameters studied were not significantly different between the two groups. Therefore, there was no clinical evidence of higher morbidity associated with prostate abnormalities in taxi drivers compared to office workers.

EFFECT OF ENDURANCE EXERCISE ON CARDIORESPIRATORY FUNCTIONS AND PERFORMANCE IN DEVELOPING AGE / 体力科学

In this study the effects of endurance exercise on cardiorespiratory functions and performance in developing age were exemined in 12 year old boys. Sujects were consisted of 11 boys who had been participating in training for soccer more than 2 hours a day for 6 days per week (S) and 10 non-participating boys for control (C) . Maximal oxygen uptake (Vo<SUB>2</SUB>max), maximal heart rate (HRmax) and maximal cardiac output (Qmax) by acetylnerebreathing method were measured on the exercise on a treadmill. Five minute run was also administered.<BR>Significant differences were found in Vo<SUB>2</SUB>max (p<0.05), values of which were 2.13±0.07 1⋅min<SUP>-1</SUP> for S. and 1.86±0.08 1⋅min<SUP>-1</SUP> for C., respectively, and in Qmax (p<0.001), values of which were 17.9±1.41⋅min<SUP>-1</SUP> for S. and 12.4+0.71⋅min<SUP>-1</SUP> for C. G., respectively. There were no significant differences in HRmax and V<SUB>E</SUB> between both groups. Values of stroke volume and V<SUB>E</SUB>/Vo<SUB>2</SUB>max were significantly higher for S.. Performances on 5 minute-run were 1164 m for S. and 1083 m for C, which showed significant difference (p<0.01) . Significant correlationship (r=0.746, p<0.001) was obtained between Vo<SUB>2</SUB>max and Qmax. It was also found that the higher Vo<SUB>2</SUB>max was, the higher Qmax was attaind.