Résumé
The Major of Medical Imaging Technology (Radiotherapy Technology Orientation) in West China Medical School, Sichuan University, has been devoted to training therapists, dosimetrists, and physicists in tumor radiotherapy, and it is urgently needed to improve the practice ability of interns and standardize the teaching system. In view of the current status of the practice of students in radiotherapy technology, this article analyzes and summarizes the teaching staff construction, teaching contents, teaching methods, and other aspects, finds out the problems and challenges in the current teaching system, and puts forward suggestions for practice teaching reform.
Résumé
Objective To investigate the efficacy and adverse reaction of three-dimensional conforml radiotherapy (3DCRT) combined with thalidomide and GEMOX regimen (gemcitabine + oxaliplatin) in patients with advanced intrahepatic cholangiocarcinoma.Methods A total of 100 patients with advanced intrahepatic cholangiocarcinoma in 901 Hospital of Joint Logistics Support Force of Chinese People's Liberation Army from March 2015 to June 2018 were divided into chemotherapy group (n =50) and combination group (n =50) by random number table method.The chemotherapy group was treated with thalidomide and GEMOX regimen,and the combined group was treated with 3DCRT on the basis of the chemotherapy regimen.The levels of serum tumor markers,clinical efficacy and adverse reactions of patients in the two groups were compared before and after treatment.Results The levels of serum carcinoembryonic antigen (CEA),carbohydrate antigen 125 (CA125) and carhohydrate antigen 19-9 (CA19-9) in the combined group were (8.76 ± 2.69) μg/L,(76.17 ± 10.12) × 103 U/L and (169.85 ± 78.97) × 103 U/L respectively,which were significantly lower than those of (12.46 ± 3.47) μg/L,(104.56 ± 14.38) × 103 U/L,(312.45 ± 71.36) × 103 U/L in the chemotherapy group,with statistically significant differences (t =5.959,P ＜ 0.001;t =11.416,P ＜ 0.001;t =9.474,P ＜ 0.001).The clinical benefit rate and the total effective rate of the combined group were respectively 64.0％ (32/50) and 88.0％ (44/50),which were higher than those of 42.0％ (21/50) and 72.0％ (36/50) in the chemotherapy group,with statistically significant differences (x2 =4.857,P =0.028;x2 =4.000,P =0.046).The incidences of leukopenia,nausea and vomiting,constipation and alopecia of patients in the combined group were 20.0％ (10/50),24.0％ (12/50),30.0％ (15/50) and 12.0％ (6/50) respectively,which were 14.0％ (7/50),16.0％ (8/50),24.0％ (12/50) and 8.0％ (4/50) respectively in the chemotherapy group,with no statistically significant differences (x2 =0.638,P =0.424;x2 =1.000,P =0.317;x2 =0.457,P =0.499;x2 =0.444,P =0.505).Conclusion 3DCRT combined with thalidomide and GEMOX regimen can significantly reduce the levels of serum tumor markers in patients with advanced intrahepatic cholangiocarcinoma,enhance the short-term efficacy without significantly increasing and aggravating adverse reactions.
Résumé
Objective To discuss the necessity and feasibility of application of virtual reality (VR) technology in the teaching course of radiotherapy technology based on the contradictions between the theory and practice of current teaching mode.Methods After in-depth analysis of the characteristics of the existing disciplinary teaching mode,VR technology was introduced to design software,glasses,operating handles and establish a special interactive platform. The teaching courses could be delivered via mobile phone side AR, helmet and AR, touch screen and PC virtual simulation with VR virtual simulation, etc. Six processes of radiotherapy were tested through online courses and offline groups to analyze the feasibility of this technology applied in the training of radiotherapy professionals. Results After the design of software and hardware and the analysis of test results,the online teaching could be utilized to write interactive programs,build virtual experience scenes, create course resource database and construct practical training courses and teaching system. The offline practice test could be applied to the simulation learning of feedback of the whole process, which possessed feasibility and development value. It could be applied to the theory and practice teaching of radiation therapy technology,making the teaching more convenient,vivid and intuitive. Conclusions VR technique combined with radiotherapy technology training can be delivered through online and offline teaching courses of theory and practice by using the plane and virtual simulation technology, which is convenient, quick and highly efficient and deserves widespread application.