RÉSUMÉ
The dried roots of Angelica sinensis has been widely applied in clinical care due to its efficiencies in nourishing and activating blood, regulating female menstrual disorders and relieving pains, relaxing bowels, etc. The cultivated two-year-old plants normally harvested roots for medicinal uses emerge over 30% early bolting rate, which leads to the lignified roots that are useless in medicinal agents. The early bolting and flowering that are leading to serious yield reduction has been one of the most serious problems in the production of A. sinensis for many years. Here, based on previously published research articles, monographs, patents as well as practice experiences, the research progresses on the internal and external factors affecting bolting and flowering of A. sinensis, the pathways regulating bolting and flowering, the mechanism revealing bolting and flowering by biotechnological interventions were summarized, with the aim of providing effective pathways jointly internal and external factors for regulating bolting and flowering, as well as references for further revealing the mechanism of the bolting and flowering of A. sinensis.