Autoregressive spatial modeling of possible cases of dengue, chikungunya, and Zika in the capital of Northeastern Brazil

Abstract INTRODUCTION: Dengue, chikungunya, and Zika are a growing global health problem. This study analyzed the spatial distribution of dengue, chikungunya, and Zika cases in São Luís, Maranhão, from 2015 to 2016 and investigated the association between socio-environmental and economic factors and hotspots for mosquito proliferation. METHODS: This was a socio-ecological study using data from the National Information System of Notifiable Diseases. The spatial units of analysis were census tracts. The incidence rates of the combined cases of the three diseases were calculated and smoothed using empirical local Bayes estimates. The spatial autocorrelation of the smoothed incidence rate was measured using Local Moran's I and Global Moran's I. Multiple linear regression and spatial autoregressive models were fitted using the log of the smoothed disease incidence rate as the dependent variable and socio-environmental factors, demographics, and mosquito hotspots as independent variables. RESULTS: The findings showed a significant spatial autocorrelation of the smoothed incidence rate. The model that best fit the data was the spatial lag model, revealing a positive association between disease incidence and the proportion of households with surrounding garbage accumulation. CONCLUSIONS: The distribution of dengue, chikungunya, and Zika cases showed a significant spatial pattern, in which the high-risk areas for the three diseases were explained by the variable "garbage accumulated in the surrounding environment," demonstrating the need for an intersectoral approach for vector control and prevention that goes beyond health actions.

Intestinal parasitism and socio-environmental factors among Mbyá-Guarani indians, Porto Alegre, Rio Grande do Sul, Brazil / Parasitismo intestinal e fatores socioambientais de indígenas Mbyá-Guarani, Porto Alegre, Rio Grande do Sul, Brasil

Disturbing data reveal the prevalence of intestinal parasites and their relationship with socio-environmental factors among Mbyá-Guarani Indians. The prevalence was determined by spontaneous sedimentation in water, centrifugation-floatation, and Kato-Katz. A socioeconomic questionnaire was submitted to each family. The overall prevalence of intestinal parasites was 88.7%, and 45.5% were polyparasitized. There was 90.5% prevalence of enteric parasites in children (1-12- year-old), and 85% among 13-65-year-old individuals, indicating that both age groups are extensively parasitized. The parasite load was low to moderate for geohelminths and 75% of the families did not have latrine, thus the practice of defecation occurred outdoors. These findings suggest that the multiple intestinal parasitism in the Mbyá-Guarani community is high to the point of being the rule, and that it relates essentially to the traditional lifestyle and health habits. It is urgently necessary to implement the association of anti-parasitic treatment with sanitation improvement. This should be done simultaneously with health education activities for this population.

Dados preocupantes demonstram a prevalência de parasitos intestinais e sua relação com fatores socioambientais entre indígenas Mbyá-Guarani. A prevalência foi determinada pelas técnicas de sedimentação espontânea em água, centrífugo-flutuação e Kato-Katz. Para cada família, um questionário socioeconômico foi aplicado. A prevalência geral de parasitos intestinais foi de 88,7% e 45,5% estavam poliparasitados. A prevalência em crianças (1-12 anos) foi 90,5% e em indivíduos entre 13-65 anos foi 85%, indicando que ambas as faixas etárias são amplamente parasitadas. A carga parasitária foi baixa a moderada para geohelmintos e 75% das famílias não possuem banheiro, sendo a prática da defecação feita ao ar livre. Estes achados sugerem que o poliparasitismo intestinal na comunidade Mbyá-Guarani é altíssimo, a ponto de ser a regra, e que se refere essencialmente ao estilo de vida tradicional e hábitos de saúde. Há a necessidade de aplicar urgentemente a associação de tratamento antiparasitário às melhorias sanitárias. Isto deve ser feito simultaneamente com atividades de educação em saúde para esta população.

Sobrepeso y obesidad en escolares de Brandsen en relación a las condiciones socioambientales de residencia / Overwweight and obesity in schoolchildren from Brandsen and its relationship with socio environmental characteristics of residence

Introducción. Los factores socioambientales desempeñan un papel esencial en la etiología del sobrepeso (S) y la obesidad (O) y constituyen elllamado “entorno obesogénico”. Los objetivos del presente trabajo son: a) estimar las prevalencias de sobrepeso y obesidad en escolares de 3 a 14 años del partido de Brandsen (Provincia deBuenos Aires) y b) analizar la probabilidad de ocurrencia de sobrepeso y obesidad en relación a las condiciones socioambientales de residencia. Población y métodos. Se relevaron peso y talla de 989 escolares, de ambos sexos, de 3-14 años de edad. Se determinaron S y O según los criterios de la International Obesity Task Force. Las prevalencias fueron comparadas entre sexos y edades. Los datos socioambientales, obtenidos apartir de encuestas, fueron procesados mediante Análisis de Componentes Principales (catPCA). Se empleó un Modelo Lineal Generalizado (link logit) para las variables S y O. Resultados. El 15,8% de los escolares presentó S yel 7,2% O, encontrándose diferencias estadísticas no significativas entre sexos y edades. El primer eje del análisis catPCA, discriminó con valorespositivos los casos que presentaron las mejores condiciones socioambientales y negativos las más desfavorables. Hubo mayor probabilidad de niños obesos asociada a condiciones socioambientalesadecuadas (mayor nivel educativo depadres, mayores ingresos y mejor acceso a servicios públicos), en tanto que se observó mayor probabilidad de niños con sobrepeso asociada a ambientes menos favorecidos. Conclusiones. Se concluye que la población escolar de Brandsen presenta elevadas prevalencias de sobrepeso y obesidad. La probabilidad de presentar sobrepeso es mayor en los niñosprovenientes de hogares con condiciones socioambientalesdesfavorables. La obesidad, en cambio, lo es en aquellos hogares que reúnencondiciones socioambientales favorables.

Introduction. Environmental factors play an important role in the etiology of overweight (S) and obesity (O), constituting the "obesogenic environment”. The objectives of the present study are: a) to estimate overweight and obesity prevalences in 3 to 14 years-old schoolchildrenfrom Brandsen (Provincia de Buenos Aires), and b) to analyze the probability of occurrence of overweight and obesity in relation to the socioenvironmentalconditions of resident. Population and methods. Weight and height were measured in 989 boys and girls aged 3 to 14 years. S and O were estimated following the criteria suggested by the International Obesity Task Force. The prevalences of S and O were compared between genders and ages. The socio-environmental information was gatheredaccording to surveys and processed by Categorical Principal Components Analysis (catPCA). Generalized Linear Model (link logit) against the variables S and O was employed. Results. S was found in 15,8% of schoolchildren and O in 7,2%. None significative statisticsdifferences between both genders and ages, were found. The first axis of the catPCA discriminated the cases that presented better socio-environmental conditions with positive values and those with more unfavorable conditions with negatives values. Higher probability of obese children was associated with better socio-environmental conditions (higher educational level of parents, higherincome and better access to public services), and higher probability of overweight children was associated with less favored environments.Conclusions. The schoolchildren population of Brandsen presents high overweight and obesity prevalences. The chance of presenting overweight is higher in children from householdswith adverse socio-environmental conditions. On the contrary, obese children are to be more found in households which have more favorablesocio-environmental conditions.