Frequency of A2B Among the AB Blood Group Donors

Objective: The aim of the study is to detect the frequency ofA2B blood groups among the AB donors.Method: This cross-sectional observational study which wascarried out at Transfusion Medicine department, BangabandhuSheikh Mujib Medical University, Dhaka from January 2018 toJuly 2018 over 142 subjects. After selection of healthy donorsblood group was detected by standardized tube technique.Anti- A1 lectin study was done for all blood donors with bloodgroup AB. Based on the serological reactivity, blood group wasclassified into A2B and Rh-D negative or positive.Results: In the study, it was found that among 142 AB bloodgroup donors, majority blood donors were male 130 (91.5%)and rest were female 12 (8.5%). Among 10 A2B blood groupdonors 25% were female and 5.38% were male. More than halfdonors 78 (54.9%) belonged to age 21-30 years. The meanage was 27.68 SD±6.76 years with ranged from 18 to 50years. It was observed that 132 (93.0%) belonged to A1Bsubgroup and 10 (7.0%) belonged to A2B subgroup. The studyalso revealed that 126 (95.5%) A1B individuals were Rhpositive, 6 (4.5%) A1B individuals were Rh-negative. All A2Bindividuals were found Rh-positive.Conclusion: From our study we found that, the frequency ofA2B among the female donors is more than four times higherthan the male donors. As the A2B is the rare subgroup but thefrequency of this subgroup in this study recommend the extraattention for the physician and staff working in the TransfusionMedicine department.

Isolation and Identification of a Subgroup A Avian Leukosis Virus from Imported Meat-type Grand-parent Chickens / 中国病毒学·英文版

An exogenous avian leukosis virus (ALV) strain SDAU09C1 was isolated in DF-1 cells from one of 240 imported 1-day-old white meat-type grand parent breeder chicks. Inoculation of SDAU09C1 in ALV-free chickens induced antibody reactions specific to subgroup A or B. But gp85 amino acid sequence comparisons indicated that SDAU09C1 fell into subgroup A; it had homology of 88.8% - 90.3% to 6 reference strains of subgroup A, much higher compared to other subgroups including subgroup B. This is the first report for ALV of subgroup A isolated from imported breeders.