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1.
Tempo psicanál ; 54(2): 381-394, jul.-dez. 2022. ilus
Article Dans Portugais | LILACS-Express | LILACS, INDEXPSI | ID: biblio-1450554

Résumé

Este artigo trata da relação dinâmica da unicidade mãe-bebê, que vivencia todos os cuidados maternos e experiencia múltiplas sensações ofertadas pela preocupação materna primária. O momento inicial de ambiência satisfatória se distingue dos demais, pelo abandono quase total do narcisismo materno, em função da identificação com o bebê, tornando-se, assim, uma mãe suficientemente boa. Neste trabalho, a percepção do corpo e das vivências corporais se relacionam à constituição do psiquismo na fase primária infantil. As experiências do corpo, neste universo de sensações, e o desenvolvimento emocional se fundam à abordagem do diálogo tônico nas tensões emocionais. A teoria de Winnicott, que pinça o cuidado materno sempre que perceptualmente o bebê é pinçado, seja na capacidade perceptual auditiva ou visual, particulariza uma vivência de unidade, com uma dependência absoluta do bebê pelos cuidados da mãe. Estes primados são condições essenciais para os estados de tensão e relaxamento tônicos, em momentos alternados de necessidade e satisfação. Os estados de excitação e tranquilidade do bebê são expressos pela tensão tônica e este tipo de linguagem corporal é especialmente vivenciado pelo infante durante a maternagem, sendo um facilitador da personalização desse sujeito que já existe no mundo.


This article deals with the dynamic relationship of the mother-baby unity, which experiences all maternal care and experiences multiple sensations offered by the primary maternal concern. The initial moment of satisfactory ambience is distinguished from the others by the almost total abandonment of maternal narcissism due to identification with the baby, thus making a mother good enough. In this work, the perception of the body and bodily experiences are related to the constitution of the psyche at this stage. The body's experiences in this universe of sensations and the emotional development at this stage are based on the approach of tonic dialogue in emotional tensions. Winnicott's theory that grasps maternal care whenever the baby is perceptually grasped, whether in the auditory or visual perceptual capacity, we have there, an experience of unity, with an almost absolute dependence of the baby on the mother's care. These cares are essential conditions for tonic states of tension and relaxation, in alternating moments of need and satisfaction. The baby's states of excitement and tranquility are expressed by tonic tension and this type of body language is especially experienced by the infant during motherhood, being a facilitator of the personalization of this subject that already exists in the world.

2.
Electrolytes & Blood Pressure ; : 28-33, 2007.
Article Dans Anglais | WPRIM | ID: wpr-195947

Résumé

Urea accumulation in the renal inner medulla plays a key role in the maintenance of maximal urinary concentrating ability. Urea transport in the kidney is mediated by transporter proteins that include renal urea transporter (UT-A) and erythrocyte urea transporter (UT-B). UT-A1 and UT-A2 are produced from the same gene. There is an active tonicity-responsive enhancer (TonE) in the promoter of UT-A1, and the UT-A1 promoter is stimulated by hypertonicity via tonicity-responsive enhancer binding protein (TonEBP). The downregulation of UT-A2 raises the possibility that TonEBP also regulates its promoter. There is some evidence that TonEBP regulates expression of UT-A in vivo; (1) during the renal development of the urinary concentrating ability, expression of TonEBP precedes that of UT-A1; (2) in transgenic mice expressing a dominant negative form of TonEBP, expression of UT-A1 and UT-A2 is severely impaired; (3) in treatment with cyclosporine A, TonEBP was significantly downregulated after 28 days. This downregulation involves mRNA levels of UT-A2; (4) in hypokalemic animals, downregulation of TonEBP contributed to the down regulation of UT-A in the inner medulla. These data support that TonEBP directly contributes to the urinary concentration and renal urea recycling by the regulation of urea transporters.


Sujets)
Animaux , Souris , Protéines de transport , Ciclosporine , Régulation négative , Érythrocytes , Rein , Souris transgéniques , Recyclage , ARN messager , Urée
3.
Korean Journal of Otolaryngology - Head and Neck Surgery ; : 439-444, 2002.
Article Dans Coréen | WPRIM | ID: wpr-648744

Résumé

BACKGROUND AND OBJECTIVES: The inner ear is an organ used for hearing and balance. For its normal function, the inner ear fluid homeostasis is required. There has been controversy over the regulatory mechanisms of maintaining inner ear fluid balance, and they have not yet been clearly defined. TonEBP is the protein that binds tonicity-responsive enhancer elements in the osmoprotective gene, which elevates the compatible osmolytes, which in turn induces cell survival in hypertonic condition. The aim of this study was to elucidate if there is an osmoregulatory mechanism in cochlea. Material and Method: The localization of TonEBP in the cochlea of male Sprague-Dawley rats was studied by immunohistochemistry with an anti rabbit polyclonal anti-rat TonEBP antibody. RESULTS: TonEBP was expressed at outer hair cells, Deiter cells, spiral ligaments, sprial limbus connective tissues, and epithelial lining of basilar membrane facing scala tympani. CONCLUSION: TonEBP in cochlea is one of the proteins involved in elucidating cell survival in changed tonicity during inner ear homeostasis.


Sujets)
Animaux , Humains , Mâle , Rats , Membrane basilaire , Protéines de transport , Survie cellulaire , Cochlée , Tissu conjonctif , Oreille interne , Éléments activateurs (génétique) , Poils , Ouïe , Homéostasie , Immunohistochimie , Rat Sprague-Dawley , Rampe tympanique , Ligament spiral de la cochlée , Équilibre hydroélectrolytique
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