Clinical value of magnetic resonance imaging and CT scanning in the diagnosis of acute craniocerebral injury / 中国基层医药

Objective To explore the clinical effect of magnetic resonance imaging (MRI) and CT scanning in the diagnosis of acute craniocerebral injury.Methods From October 2012 to November 2016,100 patients with acute craniocerebral injury in Zhoushan Hospital were selected.According to the order of patients admitted to hospital,they were randomly divided into observation group and control group,with 50 cases in each group.The observation group received MRI inspection,the control group received CT scanning.The clinical examination results of the two groups were compared.Results The positive rate and missed diagnosis rate of the observation group were 98.0％,2.0％,respectively,which of the control group were 72.0％,24.0％,respectively,the differences were statistically significant (x2 =26.958,17.468,all P ＜ 0.05).The detection rate of craniocerebral injury position lesion in the observation group was significantly higher than control group,the differences between the two groups was statistically significant (x2 =5.030,5.110,11.250,5.430,all P ＜ 0.05).The clinical total effective rate of the observation group was 94.0％,which was higher than 78.0％ of the control group,the difference was statistically significant (x2 =15.432,P ＜ 0.05).Conclusion The clinical value of MRI in the diagnosis of acute craniocerebral injury issuperior to CT scanning.

Characteristic analysis on the imageological sign of multi-slice spiral CT in diagnosing thin wall cystic lung cancer / 中国医学装备

Objective: To explore the characteristic of the imageological sign of multi-slice spiral CT in diagnosing thin wall cystic lung cancer. Methods: 42 patients with thin wall cystic lung cancer who underwent thin layer CT scan were enrolled in the research. And all of them were divided into parenchyma group (22 cases) and non-parenchyma group (20 cases) according to the composition of cancer tissue density. And retrospective analysis was applied to compare the imageological signs of the patients in two groups. Results: The occurrence rates of roundness, quasi-circular, spicule sign at margin and truncation sign of bronchus were 95.5%, 59.1% and 68.2% in parenchyma group, respectively. And they were significantly higher than that (65.0%, 10.0% and 5.0%) of non-parenchyma group (x2=4.481, x2=13.793, x2=17.733, P<0.05). And the occurrence rates of ground glass sign, bronchus in cystic space and blood vessel passing the interior of cystic space were 27.3%, 9.1% and 18.2% in parenchyma group, respectively. And they were significantly lower than that (75.0%, 40.0% and 70.0%) of non-parenchyma group (x2=9.546, x2=3.945, x2=11.486, P<0.05). Conclusion: The CT examination of thin wall cystic lung cancer has characteristic in a certain extent, and it can combine CT to dynamically follow up the change and pathological manifestation so as to carry out diagnosis.

Research on clinical significance of meningioma diagnosis in radiological expression of CT and MRI / 中国医学装备

Objective:To study CT and MRI radiological expression of benign and malignant meningiomas to provide a reliable evidence for clinical surgery scheme determination. Methods: The radiological and pathological data of 40 cases with meningiomas undergoing surgery in hospital were analyzed, and the benign and malignant lesions of meningiomas were judged according to imaging features such as meningioma shape, edge, signal or density, peritumorous edema, intratumorous calcification, multiple tumors, tumor brain interface status etc.Results: (1)Tumor signal or density: T1 signal inhomogeneous in 6 cases(15.0%), T2 signal inhomogeneous in 8 cases(20.0%), the signal homogeneous in 26 cases (65.0%), CT density is inhomogeneous in 15 cases(37.5%), CT density is homogeneous in 25 cases(62.5%); (2)Tumor edge: regular in 27 cases(67.5%), coarse, irregular, lobulated, with mural nodules in 13 cases(32.5%); (3)Dural tail sign in 36 cases (90.0%); (4)Skull invasion in 6 cases(15.0%); (5)Calcification within the tumor in 7 cases(17.5%); (6)Peritumoral edema in 14 cases(35.0%); (7)Multiple tumors in 6 cases(15.0%); (8)Enhance performance: Obvious homogeneous enhancement in 27 cases(67.5%), Obvious inhomogeneous enhancement in 13 cases(32.5%).Conclusion: Benign and malignant meningiomas with a certain radiological feature, the curative effect and prognosis may be properly evaluated by the radiological expression of meningiomas.

Changes of Cerebral Blood Flow by the Weak Trans-Cranial Ultrasound Irradiation in Healthy Adult Volunteers / 日本補完代替医療学会誌

In the recent aging society, many strategies against cerebral diseases including dementia are needed.As hand massage treatments promote blood flow for muscle fatigue and other disorders, ultrasonic vibration may promote cerebral blood flow.A novel, long wavelength ultrasonic vibration device with high permeation (less than 30 kHz, 2 mW/cm2) was applied to investigate cerebral blood flow before and after the frontal or occipital trans-cranial irradiation. In this study, the frontal or a mixture of the frontal and the occipital irradiation were conducted respectively on Xe gas X-ray CT, and SPECT experiments in healthy adults who did not have any excluding criteria. From the results, we confirmed that the low mill watt ultrasonic vibration emitted by the device promoted cerebral blood flow.

A Study on Dose Response of MAGAT (Methacrylic Acid, Gelatin Gel and THPC) Polymer Gel Dosimeter Using X-ray CT Scanner / 의학물리

In this study, we evaluated the dose response of MAGAT (Methacrylic Acid Gelatin gel and THPC) normoxic polymer gel dosimeters based on the X-ray CT scanner. To perform this study, we determined the proper ratio of the gel composition and acquired X-ray scan parameters. MAGAT gel dosimeters were manufactured using MAA (MethacrylicAcid) and gelatin of various concentration, irradiated up to 20 Gy. We obtained the 20 CT images from the irradiated gel dosimeters by using on a Phillips Brilliance Big Bore CT scanner with the various scan parameters. This CT images were used to determine the N(CT)-dose response, dose sensitivity and dose resolution As an amount of MAA and gelatin were increase, the slope and intercept were increase in each MAGAT gel dosimeter with various concentration of the N(CT)-dose response curve. The dose sensitivity was 0.38+/-0.08 to 0.859+/-0.1 and increased were amount of the MAA was increased or the gelatin was decreased. However, the change of gelatin concentration was very small compare to MAA. The Dose resolution (D(delta)(95%)) varies considerably from 2.6 to 6 Gy, dependent on dose resolution and CT image noise. The slope and dose sensitivity was almost ident verywith the variation of the tube voltage, tube current and slice thickness in the dose response curve, but the noise (standard deviation of averamalg CT number) was decreased when the tube voltage, tube current and slice thickness are increase. The optimal MAGAT polymer gel dosimeter based on the CT were evaluated to determine the CT imaging scan parameters of the maximum tube voltage, tube current and slice thickness (commonly used in clinical) using the composition ratio of a 9% MAA, 8% gelatin and 83% water. This study could get proper composition ratio and scan parameter evaluating dose response of MAGAT normoxic polymer gel dosimeter using CT scanner.