Résumé
Objective: To observe the clinical efficacy of acupuncture and moxibustion for functional dyspepsia (FD) due to Yang deficiency of the spleen and stomach.Methods: A total of 90 patients meeting the inclusion criteria of FD due to Yang deficiency of the spleen and stomach were randomized into an acupuncture-moxibustion group, an electroacupuncture (EA) group, and a mosapride group by the random number table method, with 30 cases in each group. The mosapride group was treated with mosapride citrate dispersible tablets. The EA group was treated with EA treatment. The acupuncture-moxibustion group was treated with additional moxibustion therapy based on the treatment in the EA group. All three groups took 10 d as one treatment course and 2 courses in total, with a 2-day interval between two courses. The traditional Chinese medicine (TCM) symptoms score, functional digestive disorder quality of life questionnaire (FDDQL) score, oral-colon transit time (OCTT), and serum glucagon-like peptide-1 (GLP-1) level was compared before and after treatment among the three groups. And the clinical efficacy was evaluated.Results: The total effective rate in the acupuncture-moxibustion group was 96.7％, which was higher than 86.7％ in the EA group and 73.3％ in the mosapride group, and the total effective rate in the EA group was higher than that in the mosapride group; the inter-group differences were all statistically significant (P<0.05). After treatment, the TCM symptom score in the three groups was lower than that before treatment (P<0.05), and the FDDQL score was higher than that before treatment (P<0.05). The change after treatment in the TCM symptom score in the acupuncture- moxibustion group and the EA group was more significant than that in the mosapride group, and the change in the acupuncture-moxibustion group was more significant than that in the EA group; the inter-group differences were statistically significant (P<0.05). The change after treatment in the FDDQL score in the acupuncture-moxibustion group and the EA group was greater than that in the mosapride group, and the change in the acupuncture-moxibustion group was larger than that in the EA group; the inter-group differences were all statistically significant (P<0.05). After treatment, the OCTT in all three groups was lower than that before treatment (P<0.05), and the serum GLP-1 level was higher than that before treatment (P<0.05); the change after treatment in the OCTT in the acupuncture-moxibustion group and the EA group was more significant than that in the mosapride group, and the change in the acupuncture- moxibustion group was more significant than that in the EA group; the inter-group differences were statistically significant (P<0.05). The change after treatment in the serum GLP-1 level in the acupuncture-moxibustion group and the EA group was greater than that in the mosapride group, and the change in the acupuncture-moxibustion group was larger than that in the EA group; the inter-group differences were statistically significant (P<0.05).Conclusion: Acupuncture and moxibustion can improve the clinical symptoms in patients with FD and enhance their quality of life, producing better effects than EA or mosapride alone. Shortening gastrointestinal movement time and increasing gastrointestinal hormone levels may be its mechanism.
Résumé
[Objective]This paper mainly introduced the etiology, pathogenesis and treatment of reflux esophagitis due to cold, and tried to help doctors of TCM explore the new thinking for clinical treatment.[Methods]Based on the relevant account of past dynasties literature of traditional Chinese medicine, clinically,we conclude that reflux esophagitis can result from pathogenic cold, inner cold and transmission between Zang and Fu organs.Moreover,we explain the corresponding treatment.In order to better describe this therapy, a clinical case was reported. [Results]Adverse rising of gastric qi is a basic TCM pathogenesis in reflux esophagitis.Syndromes due to cold can be divided into cold pathogen attacking stomach,Yang deficiency of the spleen and stomach, deficiency of kidney-YANG and liver cold.So the corresponding prescriptions are given respectively.[Conclusion]This has solid theoretical basis and important clnical significance to treat the disease from cold.Cold can come from outside, but also from the inside.For this kind of patients,we have to identify the excess cold and asthenia cold and the related zang-fu organs,then choose a flexible medication, and get a good curative effect.
Résumé
[Objective]This paper mainly introduced the etiology, pathogenesis and treatment of reflux esophagitis due to cold, and tried to help doctors of TCM explore the new thinking for clinical treatment.[Methods]Based on the relevant account of past dynasties literature of traditional Chinese medicine, clinically,we conclude that reflux esophagitis can result from pathogenic cold, inner cold and transmission between Zang and Fu organs.Moreover,we explain the corresponding treatment.In order to better describe this therapy, a clinical case was reported. [Results]Adverse rising of gastric qi is a basic TCM pathogenesis in reflux esophagitis.Syndromes due to cold can be divided into cold pathogen attacking stomach,Yang deficiency of the spleen and stomach, deficiency of kidney-YANG and liver cold.So the corresponding prescriptions are given respectively.[Conclusion]This has solid theoretical basis and important clnical significance to treat the disease from cold.Cold can come from outside, but also from the inside.For this kind of patients,we have to identify the excess cold and asthenia cold and the related zang-fu organs,then choose a flexible medication, and get a good curative effect.