STUDY ON HBsAg DETECTION IN FEACES OF INFECTED PERSONS WITH HBV INFECTION AND ITS INFECTIVITY / 西安交通大学学报(医学版)

HBV infection markers were oberved in the feaces of 25 newly-infected persons and 11 asymptomatic carriers, In all the 36 subjects, HBsAg was detected, with a detectable rate of 72.2%; according to the number of feaces samples, the positive rate of HBsAg was 35.2%(57/162). Of the samples of those who had HBsAg detected, the positive rate of HBeAg was 24.7%(23/93), and HBV-DNA was positive in 2 of 51 HBsAg positive samples. With immunoelectromicroscope round particles of larger clustering HBsAg were found in most of feaces samples; bacause of the use of ultracentrifugal method and monoclonal anti-HBs, their shape and size were the same as those found in HBsAg positive serum.