Advances of pathogen inactivation technology in blood components and quality evaluation / 中国输血杂志

Through the screening of blood donors, detection of pathogen antigen and antibody, full coverage of nucleic acid detection, the risk of infectious blood transfusion has been reduced to a very low level. Especially, pathogen inactivation technology (PRT) has played an irreplaceable role in ensuring blood safety. The best way to inactivate pathogens is not only to effectively remove the target pathogens in the blood, but also to maintain the activity of active ingredients in the blood to the maximum extent, and it doesn′t affect the effect of blood therapy. In this paper, the development of pathogen inactivation technology is summarized, and the influence of pathogen inactivation treatment on the quality of blood components is discussed. It provides references for improving or developing new processing technology.

Changes in potassium concentration and gene expression in mice fed a high-fat diet / 동물의과학연구지

Obesity is a risk factor for various diseases, including cardiovascular disease, diabetes, renal disease, hypertension, cancer, and neural disease. Adipose tissue in animals is important for the mobilization of lipids, milk production, deposition of fat in different depots, and muscle and meat production. Understanding the genetic and physiological causes of metabolic disease is a priority in biomedical genome research. In this study, we examined several variables in mice fed a high-fat diet, including serum composition, body weight, total calorie intake, and differentially expressed genes. Body weight and blood glucose levels were not significantly different between animals fed high-fat and normal diets. However, high-fat diet groups showed reduced calorie and food intakes. Levels of sodium, ionized calcium, glucose, hematocrit, hemoglobin, pH, PCO2, PO2, TCO2 +, HCO3 +, base excess, and SO2 in the blood were not significantly different between mice fed high-fat and normal diets. Serum potassium concentration, however, was lower in mice a high-fat diet. Differentially expressed genes were also compared between the two groups. The purpose of this study was to discover new genes as a result of annealing control primer (ACP) PCR using 20 random primers. Five down regulated genes were identified and three of others were upregulated by high-fat diet. Known genes were excluded from this result. In addition, the relationships among candidate genes and high-fat diet should be investigated according to potassium concentration in the blood. In conclusion, mice fed normal and high-fat diets showed no significant difference in body weight, whereas high-fat diet led to changes in blood composition and differential expression of several genes. These findings may provide a better understanding of the mechanisms underlying the association between obesity and metabolic diseases.

A comparison of health related habits, nutrition knowledge, dietary habits, and blood composition according to gender and weight status of college students in Ulsan

This study was carried out to obtain information related to life styles, nutrition knowledge, and dietary habits according to gender and weight status of college students in Ulsan. The subjects were 324 college students (144 males, 180 females), and they were divided into three groups based on BMI. The average BMI was 21.0 kg/m2, and the BMI of underweight, normal, and overweight students were 15.4%, 63.0%, and 21.6%, respectively. Among the male students, 0.1% and 34.0%, and among the female subjects, 27.2% and 11.7%, were included in the underweight and overweight groups, respectively. For dietary habits, the rate of skipping breakfast (34.9%) was considerably higher than those skipping lunch and dinner. Overall, the nutrition knowledge score, which was assessed by 15 questions, was somewhat low (44.9/100), yet, it was higher in females than in male students. There were significant differences among gender and weight status in several items of dietary habits such as the speed of eating meals, consuming breakfast on a regular basis, and sleeping hours. 40% of the subjects had appropriate knowledge about high calorie foods with low nutritional value. In the blood analysis of the subjects, males had higher hemoglobin levels than females. Further, more females were included in the risk group of Hb, total cholesterol, and LDL. These results suggest that in order to develop nutrition education programs for college students, differences between gender and weight status, dietary habits, and nutrition knowledge level should be considered.

Effects of Weight Control Program on Dietary Habits and Blood Composition in Obese Middle-Aged Women

The purpose of this study was to investigate the effects of weight control program on dietary habits and blood composition in obese middle-aged women. The program consisted of nutrition education, physical exercise and nutrition counseling was conducted for 12 weeks. Participants of the preliminary study were 255 obese women, among which 82 women participated in the nutrition education program. We evaluated the anthropometry, blood lipid profiles, dietary habits of obese women before and after the nutrition education. Dietary habits of the subjects were significantly improved in regularity of having breakfast (p < .05), the frequency of eating snack after dinner (p < .001), eating out (p < .01) and the speed of meal (p < .05) after the program. There was significant decrease in total cholesterol, triglyceride, LDL-cholesterol and systolic pressure of the subjects after nutrition education. Changes of atherogenic index and diastolic pressure were not significant, but had a tendency to decrease. All of the anthropometric outcomes except lean body mass such as BMI, percent body fat, fat mass, and WHR were significantly decreased after weight control program. These findings show that weight control program including nutrition education and counseling can improve dietary habits and weight control pattern, and lead the authors to recommend that public health organizations and dietetic professionals should educate obese women on practical strategies for an effective weight management.

A Study of Nutritional Intakes, Food Preference and Blood Composition in Female College Students with Premenstrual Syndrome / 대한지역사회영양학회지

This study was performed to investigate nutritional intakes and preference food and blood composition of female college students of premenstrual syndrome. Based on physical measurement test results, both groups showed no noticeable difference and both groups were within the normal range according to body composition analysis. In terms of nutrients consumption, results showed nutritional intakes more than EAR (estimated average requirements) included phosphorus > vitamin B6>vitamin B1, while nutritional intakes less than EAR were vitamin A > vitamin B2> calcium > folic acid. A significant difference was observed for vitamin C intake (p < 0.05). The overall mean values of basic blood (WBC, RBC, Hct, and Hb), sex hormone (Estrogen, Progesterone), aldosterone, cortisol, Cu, Zn, and Ca, Mg indices in female college students were within the normal range and there was no significant difference between the PMS group and the Normal group. In conclusion, vitamin C intake of the PMS group showed a level of 84.8% EAR. Therefore vitamin C supplement can be beneficial to relieve the PMS Syndrome.

A Study of Nutritional Intakes, Food Preference and Blood Composition in Female College Students with Premenstrual Syndrome / 대한지역사회영양학회지

This study was performed to investigate nutritional intakes and preference food and blood composition of female college students of premenstrual syndrome. Based on physical measurement test results, both groups showed no noticeable difference and both groups were within the normal range according to body composition analysis. In terms of nutrients consumption, results showed nutritional intakes more than EAR (estimated average requirements) included phosphorus > vitamin B6>vitamin B1, while nutritional intakes less than EAR were vitamin A > vitamin B2> calcium > folic acid. A significant difference was observed for vitamin C intake (p < 0.05). The overall mean values of basic blood (WBC, RBC, Hct, and Hb), sex hormone (Estrogen, Progesterone), aldosterone, cortisol, Cu, Zn, and Ca, Mg indices in female college students were within the normal range and there was no significant difference between the PMS group and the Normal group. In conclusion, vitamin C intake of the PMS group showed a level of 84.8% EAR. Therefore vitamin C supplement can be beneficial to relieve the PMS Syndrome.

A Study on Relation between Premenstrual Syndrome (PMS) and Nutritional Intake, Blood Composition of Female College Students / 대한지역사회영양학회지

This study was performed to investigate the correlation between Premenstrual syndrome (PMS) and nutritional intake, blood composition of female students. One hundred and one female students were selected as the experimental subjects at Gyeongsang National University. To assess the PMS symptoms of the subjects, a questionnaire (PAF) score based on the methods of Halbreich, Endicor and Nee was prepared with 34 different items. Dietary survey was conducted by 24-hour recall method for 3 days and nutrient intakes were analyzed by the CAN-Pro. Blood composition of WBC, RBC, Hb, Hct, Ca and Mg was measured. The average height, weight and BMI of subjects were 160.7 +/- 4.6 cm, 54.1 +/- 5.7 kg and 21.2 +/- 1.9, respectively. Average intakes of energy, calcium, iron, zinc, vit B2, and folic acid per day were 1810.2 +/- 344.9 kcal (90.5% of RDA), 621.1 +/- 197.3 mg (88.7% of RDA), 15.9 +/- 4.9 mg (99.3% of RDA), 8.1 +/- 3.4 mg (80.5% of RDA), 1.1 +/- 0.6 mg (88.3% of RDA) and 234.3 +/- 78.6 microgram (93.7% of RDA), respectively. Score of the behavioral symptoms, psychologic symptoms, physical symptoms and other symptoms were recorded 1.79 +/- 0.86, 2.11 +/- 1.08, 2.31 +/- 1.11 and 1.58 +/- 0.86, respectively. The relation between PMS and menstrual cramps was significant. A significant difference was observed for menstruation amount in physical symptoms (p < 0.05) and other score (p < 0.05). The group who drinks alcohol over 30 g per day showed higher scores at total PAF (p < 0.05), psychologic symptoms (p < 0.05), physical symptoms (p < 0.05), and other scores (p < 0.05) than those who don't drink alcohol. Calcium in the blood showed a negative correlation with total PAF score (p < 0.05), behavioral symptoms (p < 0.05), physical symptoms (p < 0.05) and other scores (p < 0.01). Magnesium in the blood showed a negative correlation with physical symptoms (p < 0.05), other score (p < 0.05). WBC was negatively associated with psychologic scores (p < 0.05). Hb and Hct were negatively associated with other scores (p < 0.05). In conclusion, calcium intake showed a level of 88.7% of RDA and this study revealed that there is a correlation between PMS and blood composition in female college students. Therefore, calcium and magnesium supplements can be beneficial to relieve PMS symptoms.

Investigation on Donors' Blood Lipoids,Blood Composition and Hemorrheological Indexes / 中国输血杂志

A comparison between 70-blood-donor and 70-health-control blood lipoids,blood composition,and hemorrheological indexes by paired analysis method basedon occupation,sex and age was made.Paired T-test showed that though severalindexes of the blood donors reduced remarkably,they were still within the normalphysiological limits,There were no abnormal findings through physical examinationand ECG,indication that according to the general physique and present diet condi-tions of Chinese population.It is safe to donate 300ml blood once at intervals of three months.