Résumé
Objective To investigate the clinical efficacy of carboprost tromethamine injection and misoprostol in high-risk of maternal postpartum. Methods 60 maternal with high-risk postpartum hemorrhage from January 2012 to January 2017 were divided into the control group and study group,30 case in each group.The two groups were treated with cesarean section surgery, the control group received misoprostol sublingual, study group were treated with carboprost tromethamine injection by intramuscular injection, recorded two groups of postpartum hemorrhage andthe incidence of adverse reactions. Results The study group of 2h postpartum hemorrhage, 24 h postpartum hemorrhage were significantly lower than control group (P<0.05); the incidence of adverse drug reactions in study group was 10.00%, and control group was 13.33%, there is no significant difference. Conclusion Carboprost tromethamine injection was effective and safe in the prevention of postpartum hemorrhage, which was beneficial to the quality of life and safety of high-risk postpartum women.
Résumé
Objective To investigate the clinical efficacy of carboprost tromethamine injection and misoprostol in high-risk of maternal postpartum. Methods 60 maternal with high-risk postpartum hemorrhage from January 2012 to January 2017 were divided into the control group and study group,30 case in each group.The two groups were treated with cesarean section surgery, the control group received misoprostol sublingual, study group were treated with carboprost tromethamine injection by intramuscular injection, recorded two groups of postpartum hemorrhage andthe incidence of adverse reactions. Results The study group of 2h postpartum hemorrhage, 24 h postpartum hemorrhage were significantly lower than control group (P<0.05); the incidence of adverse drug reactions in study group was 10.00%, and control group was 13.33%, there is no significant difference. Conclusion Carboprost tromethamine injection was effective and safe in the prevention of postpartum hemorrhage, which was beneficial to the quality of life and safety of high-risk postpartum women.
Résumé
Objective To investigate clinical efficacy and safety of carboprost tromethamine injection combined with low B -Lynch suture for intractable postpartum hemorrhage placenta previa.Methods 125 cases of intractable postpartum hemorrhage placenta previa were divided into two groups according to treatment(n =62)with the observation group(n =63),the control group was administered oxytocin,and the line in the placental separation surface 8 interrupted suture;the observation group was used carboprost tromethamine injection combined with low B -Lynch suture.Clinical efficacy,blood loss,bleeding,postoperative bleeding 2h,24h after blood loss,transfusion rate and index sex hormone levels were compared before and after treatment.Results (1)After treatment,total effec-tive rate of the control group and observation group was 77.42%(48 /62)and 95.24%(60 /63)respectively.There was a statistically significant difference between the two groups(P 0.05),and after treatment,the index level differences were not statistically significant(P >0.05);(4)the two groups during treatment,liver and kidney functions were normal,three cases of the control group and two cases of the observation group occured nausea and vomiting.Conclusion Carboprost tromethamine injection combined with low B -Lynch suture has significant effect, a small amount of bleeding,high security for intractable postpartum hemorrhage placenta previa,which should be promoted.
Résumé
Objective To observe the curative effects of carboprost tromethamine injection in treatment of postpartum hemorrhage due to uterine inertia.Methods The clinical data of 118 patients with postpartum hemorrhage due to uterine inertia were analyzed retrospectively.The patients were divided into control group (68 cases) and observation group (50 cases) by treatment method.The patients in control group were given conventional treatment while the patients in observation group were given carboprost tromethamine injection on basis of conventional treatment.The postpartum blood loss after 2,24 h after treatment,the third labor time and therapeutic effects in two groups were recorded and compared.The patients in control group took carboprost tromethamine injection if conventional treatment did not work and all patients should have surgery immediately if repeatedly carboprost tromethamine injection were invalid; adverse reactions of using carboprost tromethamine injection were closely watched.Results The postpartum blood loss after 2,24 h after treatment in control group was (676 ± 86),(751 ± 70) ml,which was higher than that in observation group [(238 ± 62),(281 ± 56) ml],and there was significant difference (P ＜ 0.05).The third labor time in control group was (5.1 ± 1.9) h,which was longer than that in observation group [(2.1 ± 1.4) h],and there was significant difference(P＜ 0.05).After conventional treatment with 47 patients stopped bleeding in control group,and the effective rate was 69.1％ (47/58),while the effective rate in observation group was 96.0％ (48/50),and there was significant difference (P ＜ 0.05).Twenty-one patients in control group accepted carboprost tromethamine injection after treatment,while the traditional therapy did not work,and the effective rate increased to be 95.2％ (20/21).Among carboprost tromethamine injection treatment of 71 patients,2 cases' blood pressure increased,2 cases had facial blushing,1 case with mild headache,3 cases of diarrhea and 3 cases of nausea and vomiting (a total of 11 cases),and the incidence rate was 15.5％ (11/71),which was relatively minor.All patients were given symptomatic treatment and all rell eased within 24 h,and there were no other serious adverse reactions.Conclusion Using carboprost tromethamine injection to treat postpartum hemorrhage due to uterine inertia has more remarkable curative effects and higher clinical safety,which is worthy of clinical promotion.