Recent advances in the application of nanobody technology: a review / 生物工程学报

As a malleable and novel tool for antigen recognition and modulation, nanobodies have the advantages of small size, easiness of expression, screening and modification, as well as high affinity and stability. Nanobodies are capable of recognizing more cryptic antigenic epitopes that are difficult to be recognized by traditional antibodies, making them increasingly used in the diagnosis and treatment of various diseases and assays. Nanobodies are also playing an irreplaceable role in the basic research. This review summarized the recent development of nanobodies and their derivatives in the detection of small molecules, pathogenic microorganisms and diagnosis of diseases, as well as in the fields of targeted therapies, cellular and molecular imaging. Broad prospects of nanobodies in the field of protein conformation studies were also reviewed.

Preface for special issue on veterinary biotechnology (2017) / 生物工程学报

Veterinary biotechnologies that represent the applications of biotechnologies in veterinary science are advancing rapidly in the last decade in spite of relatively late kickoff. This special issue consists of four sections, reviews, new technologies, new methods and others, presenting the recent progress in diagnostic assays, vaccines and others of emerging and reemerging animal infectious diseases.