Traditional Uses and Anticancer Potential of the Combretum Genus: A Literature Review

Background: Cancer incidence is increasing annually in all countries. So, it is nowadays a great burden for the different nations of the world. Research for new therapeutics is becoming an urgent need, particularly for intractable and chemoresistant cancer cases. The solutions can still be found by investigating natural products which are recognized as promising sources of bioactive compounds with a potential for the discovery of new preventive and therapeutic anticancer agents. Methodology: The present work used databases such as Pubmed, Science Direct and Google scholar to investigate the ethnobotanical uses of some Combretum species in the literature. It also allowed us to summarize some pharmacological studies on Combretum species. Results: This review gathers all available traditional uses and cytotoxicity studies of Combretum species in the literature. Special focus is given to pharmacological studies highlighting isolated potential anticancer molecules. These molecules present potent cytotoxic effect on various cancer cell lines and may contribute to improving the health of people suffering from various cancer diseases. Conclusion: The Combretum species are widely used in folk medicine for the treatment of several pathologies including cancers. This study is of fundamental importance in highlighting Combretum species as a potential source for research of new anticancer compounds.

Plantas medicinales, comestibles y aromáticas de una ciudad patagónica de Argentina: características y potencialidades de un recurso poco explorado / Medicinal, edible and aromatic plants in hedges of a patagonian city of Argentina: characteristics and potential of a resource little explored

Los cercos vivos urbanos tienen un rol significativo por ser reservorios de biodiversidad y por las funciones socioeconómicas que pueden sustentar. En Bariloche (Río Negro, Patagonia Argentina) se estudiaron 300 cercos familiares, la riqueza de especies leñosas componentes, sus usos medicinales y comestibles, presencia de aromaticidad, como así también su disponibilidad en comercios locales. Los cercos se componen de 86 especies, entre estas las más frecuentes son las exóticas: Cytisus scoparius, Pseudotsuga menziesii, Cupressus macrocarpa y Rosa sp., y las nativas: Chusquea culeou y Nothofagus antarctica. El 73 por ciento de las especies son medicinales, el 59 por ciento comestibles y el 33 por ciento. Solo el 24 por ciento de las especies están disponibles en comercios de la ciudad dedicados a la venta de alimentos y/o productos herbolarios. Se concluye que los cercos de Bariloche tienen un alto potencial para la complementación, diversificación de la dieta y el tratamiento de dolencias menores de los pobladores locales.

Urban hedges have a significant role to be reservoirs of biodiversity and socio-economic functions that it can sustain. In Bariloche (Río Negro, Patagonia Argentina) we studied 300 family hedges, the richness of woody components, their medicinal and edible uses, presence of aromaticity, as well as their availability in local stores. The hedges are composed of 86 species, among these the most common are the exotics: Cytisus scoparius, Pseudotsuga menziesii, Cupressus macrocarpa y Rosa sp., and the natives: Chusquea culeou and Nothofagus antarctica. 73 percent of these one are medicinal, 59 percent are edible and 33 percent are aromatic plants. Only 24 percent of the species are available in shops of the city dedicated to the sale of food and/or herbal products. We conclude that the hedges of Bariloche have a high potential for supplementation, dietary diversification, and treatment of minor ailments of the local people.

Ethnobotanical inventory and medicinal uses of some important woody plant species of Kotli, Azad Kashmir, Pakistan

To document ethnobotanical informations of useful woody plant species in the region of Kotli, Azad Kashmir. Methods: An ethnobotanical survey was conducted in Kotli. Data were collected by interview and semi structured questionnaire from selected local informants and traditional practitioners as well as by field assessment. Results: The present study documented the etnobotanical uses of 33 woody plant species. Most of the species have been used for dual purpose. Only 5 species are used for one purpose. Study revealed all species have medicinal value, among which 21 were used as fuel wood species, 16 as fodder species, 4 as timber wood species, 12 as edible fruit species, 6 as fence or hedge plant, 7 as ornamental species and 12 species had other uses. Conclusions: Medicinal plants are still widely used for health care by locals of Kotli. Some species of woodlands seem to be vulnerable to overcollection and deforestation. As the young generation is diverted toward allelopathic medicines, ethnobotanical knowledges of important medicinal plants are restricted to the old people only. It is suggested to close the forest of district Kotli for next two to three decades for the conservation of plant biodiversity.

Ethnobotanical inventory and medicinal uses of some important woody plant species of Kotli, Azad Kashmir, Pakistan

Objective: To document ethnobotanical informations of useful woody plant species in the region of Kotli, Azad Kashmir. Methods: An ethnobotanical survey was conducted in Kotli. Data were collected by interview and semi structured questionnaire from selected local informants and traditional practitioners as well as by field assessment. Results: The present study documented the etnobotanical uses of 33 woody plant species. Most of the species have been used for dual purpose. Only 5 species are used for one purpose. Study revealed all species have medicinal value, among which 21 were used as fuel wood species, 16 as fodder species, 4 as timber wood species, 12 as edible fruit species, 6 as fence or hedge plant, 7 as ornamental species and 12 species had other uses. Conclusions: Medicinal plants are still widely used for health care by locals of Kotli. Some species of woodlands seem to be vulnerable to overcollection and deforestation. As the young generation is diverted toward allelopathic medicines, ethnobotanical knowledges of important medicinal plants are restricted to the old people only. It is suggested to close the forest of district Kotli for next two to three decades for the conservation of plant biodiversity.

A panoramic view on phytochemical, nutritional, ethanobotanical uses and pharmacological values of Trachyspermum ammi Linn

Trachyspermum ammi Linn. (T. ammi) is an aromatic, grassy, annual plant belonging to Umbelliferae family which grows in the east of India, Pakistan, Iran, and Egypt. T. ammi has been used traditionally to treat arthritis, colic, diarrhea and gastrointestinal problems. In addition to these medicinal uses, T. ammi continues to be valued around the world as an important cooking spice and is believed to relief the common cold, flu-like symptoms, headaches, and even painful menstrual periods. These multiple uses can be explained by its several active compounds. The phytochemical studies on T. ammi seeds have revealed the presence of alkaloids, steroids, fixed oils, glycosides, tannins, saponin and flavonoids, cumene, thymene, amino acids and dietary fiber essential oils like thymol, c-terpinene, p-cymene. Several pharmacological studies on anti-tussive effect, inhibitory effect on histamine (H1) receptors, antihypertensive, antispasmodic, bronchodilator, hepato-protective, analgesic, anti-inflammatory, antioxidant and anti mutagenic activities of T. ammi seed extracts have been reported in the literature. The present review is therefore, an effort to give a detailed survey of the literature on traditional, phytochemical and pharmacological properties of T. ammi.