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Article de Chinois | WPRIM | ID: wpr-575229

RÉSUMÉ

Objective To study the effects of ethanol extracts of a Chinese medical herb stem and radix of Securidaca inappendiculata Iassk (CYT), on lymphocyte proliferation and secretion of interleukin-2 (IL-2) and tumor necrosis factor (TNF-?) of mouse spleen cells in vitro. Methods Different concentrations of ethanol extracts of CYT were added to mouse spleen cell cultures supplemented with ConA. Lymphocyte proliferation reaction was detected by MTT assay. IL-2 and TNF-? secreting level were measured by ELISA. Results Ethanol extract of Securidaca inappendiculata Hassk increased cultured mouse spleen cell proliferation and secretion of IL-2 and TNF-B in the presence of ConA. Conclusion Ethanol extracts of CYT could raise mouse lymphocyte activities in vitro.

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