1.
Chinese Pharmacological Bulletin
;
(12)1986.
Article
Dans Chinois
| WPRIM
| ID: wpr-556421
Résumé
Survivin is a member of the IAP family, which has been shown to localize to various components of the mitotic apparatus. Survivin is not only an apoptosis inhibitor, but a mitotic regulator as well. Survivin is Absolutely undetectable in normal tissues, but over-expressed in all the most common human cancers. Survivin is considered as an important target in cancer treatment, and the research on its molecular antagonists has gained encouraging achievements.