Résumé
The domestic production of moxa used in Japanese moxibustion therapy has decreased. Therefore, it is assumed that improved productivity of moxa and cultivation of Artemisa princeps Pamp. (Yomogi) is necessary for stable production of moxa. In this study, the production rate of moxa processed from green leaves, its chlorophyll content, maximum temperature of combustion, morphology, and yield of families collected from 127 domestic spots were investigated. They were evaluated to determine which family was suitable for use in moxibustion. As a result of principal component analysis on the morphological evaluation, 22 families were extracted as they were easily harvestable and were produced over a large area. They had a high productivity rate for moxa, and contained more than the standard weight in dry leaves among all the families. It was confirmed that these extracted families included families that have not been used so far in addition to families collected in conventional areas. These results suggest that production using extracted families can improve the domestic production of Artemisa princeps of moxa.
Résumé
Abstract Introduction Infertility has a high prevalence in the general population, affecting 5 to 15% of couples in reproductive age. The assisted reproduction techniques ( ART ) include in vitro manipulation of gametes and embryos and are an important treatment indicated to these couples. It is well accepted that the implantation rate is positively influenced by the morphology of transferred embryos. However, we question if, apart from the assessment of embryo morphology, the number of produced embryos per cycle is also related to pregnancy rates in the first fresh transfer cycle. Purpose To evaluate the clinical pregnancy rate according to the number of formed embryos and the transfer of top quality embryos ( TQEs ). Methods In a retrospective cohort study, between January 2011 and December 2012 , we evaluated women who underwent intracytoplasmic sperm injection (ICSI), aged < 40 years, andwith at least 1 formed embryo fresh transferred in cleavagestage. These women were stratified into 3 groups according to the number of formed embryos (1 embryo, 2-3 and ≥ 4 embryos). Each group was divided into 2 subgroups according to the presence or not of at least 1 transferred TQE (1 with TQE; 1 without TQE; 2-3 with TQE, 2-3 without TQE; ≥4with TQE; ≥4withoutTQE). The clinicalpregnancy rateswerecomparedineach subgroup based on the presence or absence of at least one transferred TQE. Results During the study period, 636 women had at least one embryo to be transferred in thefirst fresh cycle (17.8% had 1 formed embryo [32.7% with TQEversus 67.3% without TQE], 42.1% of women had 2-3 formed embryos [55.6% with TQE versus 44.4% without TQE], and 40.1%ofpatientshad ≥4 formedembryos[73.7%withTQEversus26.3%withoutTQE]).The clinical pregnancy rate was significantly higher in the subgroup with ≥4 formed embryos with at least 1 transfered TQE (45.2%) compared with the subgroup without TQE (28.4%). Conclusions Having at least two available embryos and at least one TQE for embryo transfer are predictors of the pregnancy rates.
Resumo Introdução A infertilidade tem uma alta prevalência na população geral, afetando 5 a 15% dos casais em idade reprodutiva. As técnicas de reprodução assistida ( TRA ) incluem a manipulação in vitro de gametas e embriões e são um importante tratamento indicado para esses casais. Sabe-se que a taxa de implantação é positivamente influenciada pela morfologia dos embriões transferidos. No entanto, questiona-se, se além da avaliação da morfologia do embrião, o número de embriões produzidos por ciclo também está relacionado com as taxas de gravidez do primeiro ciclo de transferência fresco. Objetivo Avaliar a taxa de gravidez clínica de acordo com o número de embriões formados e a transferência de embrião com ótima morfologia ( EOM ). Métodos Em um estudo de coorte retrospectivo, entre janeiro de 2011 e dezembro de 2012, avaliamos mulheres submetidas a ICSI com idade < 40 anos e com pelo menos um embrião formado e transferido a fresco em estágio de clivagem. Estas mulheres foram estratificadas em 3 grupos de acordo com o número de embriões formados (1 embrião, 2-3 e ≥ 4 embriões). Cada grupo foi subdividido em 2 subgrupos de acordo com a presença ou não de EOM transferido (1 com EOM; 1 sem EOM; 2-3 com EOM; 2-3 sem EOM; 4 com EOM; ≥4 sem EOM). As taxas de gravidez clínica foram comparadas em cada subgrupo segundo a presença ou não de pelo menos um EOM transferido. Resultados Durante o período do estudo, 636 mulheres tiveram pelo menos 1 embrião para ser transferido no primeiro ciclo a fresco (17,8% possuíram 1 embrião formado [32,7% com EOM versus 67,3% sem EOM], 42,1% das mulheres apresentaram 2-3 embriões formados [55,6% com EOM versus 44,4% sem EOM], e 40,1% das pacientes formaram ≥4 embriões [73,7% com EOM versus 26,3% sem EOM]). A taxa de gravidez clínica foi significativamente maior no subgrupo com ≥4 embriões formados com transferência de pelo menos 1 EOM (45,2%) comparando-se ao subgrupo sem EOM (28,4 % ). Conclusões Ter pelo menos dois embriões e pelo menos um EOM para transferência são fatores preditivos da taxa de gravidez.
Sujets)
Humains , Femelle , Grossesse , Adulte , Transfert d'embryon/statistiques et données numériques , Embryon de mammifère/anatomie et histologie , Taux de grossesse , Injections intracytoplasmiques de spermatozoïdes , Études de cohortes , Études rétrospectivesRésumé
Aims: The aim of this experiment is to study the effect of flaxseed on lipid profile, antioxidant activity and ATP-cassette binding proteins G5 and G8 (ABCG5 and G8) levels in the liver of diabetic rat. Place and Duration of Study: Department of Biochemistry and Physiology Research Centre, Afzalipour School of Medicine, Kerman University of Medical Sciences(Kerman, Iran), between 2008 and 2011. Methodology: rats randomly were divided into three groups: diabetic rat + flaxseed (treatment group), diabetic rat (control group I), healthy rat (control group II). Afterward one month Serum lipid parameters and also Super oxide dismutase (SOD) activity, reduced glutathione (GSH) and malondialdehyde (MDA) levels were measured. ABCG5 and ABCG8 levels were determined by RT-PCR. Results: Flaxseed markedly reduced malondialdehyde (MDA), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), very low density lipoprotein cholesterol (VLDL-C) (all of them P<0.05). GSH, SOD (P<0.05) as well as liver ABCG5 and ABCG8 were significantly increased (P<0.01) in flaxseed treatedanimals compared with diabetic group. Conclusion: The results of this experiment showed that flaxseed has antioxidant and ani-atherogenic effect. This plant reduced cholesterol levels may be via ABCG5 and ABCG8 transporters in diabetic rats.
Résumé
Aims: To perform a) a topographical analysis of the bracket slot of 12 as-received stainless steel brackets and of in vivo used stainless steel brackets from 7 patients and b) a compositional characterization of the constituting materials of two types of brackets. Study Design: In vitro laboratory study. Methodology: 12 as-received brackets and in vivo used brackets of seven patients were analysed. Two commercially available brackets were used for this study. A SEM analysis evaluated the topographic features of each bracket slot while an EDAX analysis was performed to analyse the constituting parts of each bracket. Results: As-received ORMCO brackets show more traces of plastic deformation than GAC brackets. On the contrary, pits, crevices and grain boundaries were observed on all as-received brackets. An increased plastic deformation and amount of scratches was noticed on ORMCO and GAC brackets after orthodontic treatment. Elemental analysis revealed that base and wing materials were not identical in GAC nor in Ormco brackets. In addition, both ORMCO and GAC brackets consist each of two parts assembled using a different brazing material. Conclusion: Both as-received brackets show different damage patterns on their slot surface. Increase of damage patterns was visualized after intra-oral use. As a consequence of the use of different constituting materials for the manufacturing of the two types of brackets investigated, galvanic corrosion is likely to occur.
Résumé
Objetivo: Determinar criterios de selección de muestras para la evaluación morfológica del hemograma, basados en parámetros clínicos y resultados del contador hematológico y en términos de gestión, costos y clínica, los resultados de un programa de selección de muestras para la evaluación morfológica del examen en un hospital tipo 1. Pacientes, Materiales y Método: Pacientes con una muestra tomada en el Hospital de Carabineros de Chile durante el mes de Agosto de 2009, las que fueron analizadas en un equipo Beckman Coulter HmX@ y evaluadas morfológicamente por el Tecnólogo Médico. Se registraron los parámetros clínicos tales como hemoglobina, leucocitos y plaquetas, además del lugar de derivación, especialidad y edad del paciente. Los resultados fueron analizados, tanto por alerta clínica como instrumental, incluyendo todos los parámetros considerados clínicamente importantes. Resultados: Participaron 2.222 pacientes, hubo concordancia entre el Tecnólogo Médico y el analizador en 93,9 por ciento de los casos, con una sensibilidad de 97,3 por ciento y una especificidad de 88,9 por ciento con valores predictivos positivo y negativo de 95,9 por ciento y 92,7 por ciento respectivamente, para detectar una muestra anormal. Por criterios de selección se eliminó la evaluación morfológica en 79,5 por ciento de los casos. Hubo 1,6 por ciento de casos falso-negativos en los criterios de morfología. Discusión: El estudio demostró que es posible disminuir el número de evaluaciones morfológicas hechas al hemograma en un 80 por ciento de los casos, lo cual es semejante a los estudios internacionales efectuados en un hospital tipo 1. El sistema de alerta clínica pone énfasis en la importancia de que el médico tratante ingrese la información clínica en la solicitud de hemograma. Hay una liberación importante de tiempo de Tecnólogo Médico para utilizar su capacidad en funciones de mayor complejidad.
Objectives: To determine selection criteria for the morphological evaluation of full blood count samples, based on clinical criterias and the results of an automatic hematological analyzer. To analyze the cost-benefits and gestion of such a selection procedure in samples obtained from a public general hospital. Patients, Materials and Methods: AII patients with a full blood count taken at the Hospital de Carabineros de Chile during August 2009 were included AII samples were analyzed using a Beckman-Coulter HmX@ automatic analyzer and analyzed morphologically by the Medical Science Officer. Patient details including age, sex, hematological parameters Hemoglobin, white cell and platelet count and place of reference were noted the results were analyzed using clinical and instrument alerts, including all clinical hematological parameters considered important. Results: 2,222 patients were included in the study. There were an agreement in analysis between the HmX and Medical Science Officer in 93.9 percent of cases, with a sensitivity of 93.9 percent specificity of 88.9 percent, a positive and negative predictive value of 95.9 percent and 927 percent respectively to detect and abnormal blood count. Owing to the selection criteria used it was possible to eliminate the need for morphological evaluation in 79.5 percent of cases, the possibility of a serious error of omission being minimal, only 1,6 percent of cases were false negative, on morphological and not clinical grounds. Discussion: The study showed that it is possible to decrease the number of morphological evaluations in 80 percent of cases, which is similar to the figures internationally reported for a general hospital. The clinical alert puts emphasis on the treating physician to complete clinical details on the order form. In total, there were 1.6 percent of false negative cases on morphological grounds y it is important to note that some morphological abnormalities will not be detected the...