1.
Chinese Pharmacological Bulletin
;
(12): 159-163, 2010.
Article
Dans Chinois
| WPRIM
| ID: wpr-404035
Résumé
Population pharmacokinetics(PPK),which is based on the principle of statistics,can be used to estimate various inter- and intra-individual factors which affect pharmacokinetics.By using Bayesian estimator,PPK can predict individual pharmacokinetic parameters accurately.PPK is widely used in the immunosuppressive therapy with cyclosporine,tacrolimus,mycophenolic acid and sirolimus.