The Progression of Postmortem Biochemistry Analysis in Forensic Discrimination of Cause of Death / 中山大学学报(医学科学版)

The discrimination of the cause of death is an important part in forensic medicine. With the advantages of simple operation， high test efficiency， and easy sensitivity to the death mechanism of the deceased， postmortem biochemistry analysis has become a significant auxiliary analysis method for discrimination of the cause of death. In this paper， we discuss the development status， advantages and current problems of postmortem biochemical analysis， and then describe the application prospect of postmortem biochemistry in the discrimination of the cause of death by posing feasible solutions， so that to provide an idea for this research.

Application of Postmortem Biochemistry in Forensic Diagnosis of Diabetic Ketoacidosis / 法医学杂志

Diabetic ketoacidosis is a serious complication results from the high blood levels of glucose and ketone in diabetes mellitus patients that cause metabolic overbalance. An analysis of postmortem biochemical indexes is needed in such cases without specific signs of the routine forensic medicine examination. Postmortem biochemistry is a kind of examinations that collecting the body fluids of the corpses to determine the metabolic state of their life time to estimate the cause of death. This paper reviews the basic features and signs of the forensic medicine examination in the dead cases of diabetic ketoacidosis, and emphatically analyzes the postmortem biochemical indexes of diabetic ketoacidosis, and summarizes new ideas of forensic medicine diagnosis in diabetic ketoacidosis death.

Postmortem Biochemistry (I) : Cardiac Markers / 대한법의학회지

In cases of atherosclerotic occlusion of coronary artery, is it appropriate to conclude that myocardial infarction is the true cause of death? More sensitive and specific diagnostic methods for the postmortem diagnosis of myocardial infarction are sometimes necessary because macroscopic or microscopic changes associated with early-phase acute myocardial injuries or myocardial infarct are sometimes absent in sudden cardiac death. Postmortem biochemical assessment of cardiac markers may help to evaluate the pathological cardiac status in sudden unexpected death without obvious cause. However, forensic pathologists are generally interested only in the macroscopic and microscopic findings for postmortem diagnosis of myocardial diseases and hesitate to use postmortem biochemical data because of the risk of postmortem changes. There are several clinically useful cardiac markers antemortem cardiac events such as myocardial injuries, infarct, or heart failure and postmortem data on cardiac markers in autopsy cases of sudden death have been reported. This review of postmortem data on cardiac markers in blood, other body fluids, and myocardial tissue will serve to introduce the recent international research trends and provide a foundation for a new field in postmortem biochemistry.