Metabolic characteristics and management of polycystic ovary syndrome during pregnancy / 中国实用妇科与产科杂志

Polycystic ovary syndrome(PCOS)is the most common endocrine and metabolic disorders in women of childbearing age,which may have adverse effects on both pregnant and non-pregnant women.In recent years,it has been found that PCOS appears to increase risks of developing adverse outcomes,which may be related to insulin resistance,obesity,glucose and lipid metabolic disorders and hyperandrogenism.Proper management of PCOS in prepregnancy,preg⁃nancy and postpartum might play important roles in the prevention of short-term and long-term complications.The metabolic characteristics and management of PCOS are reviewed in this article.

Progress in pathogenesis of adverse pregnancy outcomes induced by group B Streptococcus / 中华微生物学和免疫学杂志

Group B Streptococcus ( GBS) is a leading infectious cause of adverse pregnancy out-comes such as preterm birth. GBS colonizes the vagina during pregnancy and can ascend into the uterus and then infect the fetus. It encodes a series of virulence factors such as adhesion and invasion factors, hemolytic pigments and hyaluronidase, which are important to vaginal colonization and immune evasion. Immune re-sponses to GBS cause the release of a multiple of inflammatory mediators, leading to the premature rupture of membranes, preterm birth and fetal injury. This paper reviews the pathogenesis of GBS vaginal colonization and ascending infection causing adverse pregnancy outcomes.