Effects of different materials for partial sciatic nerve ligation on glial cell activation in rat models of chronic constriction injury / 南方医科大学学报

OBJECTIVE@#To compare the effects of different materials for partial sciatic nerve ligation on glial cell activation in the spinal cord in a rat model of chronic constriction injury (CCI).@*METHODS@#SD rats were randomly divided into the sham group (=15), silk suture CCI group (=15) and chromic catgut CCI group (=14). The mechanical withdrawal threshold (MWT) and thermal withdrawal latency (TWL) of the rats were detected at 3, 7, 11 and 15 days after the operation. The changes in the sciatic nerve, the activation of spinal cord glial cells and the expression of inflammatory factors were observed using Western blotting and RT-PCR.@*RESULTS@#At 3 to 15 days after the surgery, MWT and TWL of the rats were significantly lower in silk suture group and chromic catgut group than in the control group ( < 0.05), and was significantly lower in chromic catgut group than in the silk suture group ( < 0.05) at 3 days after the surgery. The results of sciatic nerve myelin staining showed that the sciatic nerve was damaged and demyelinated in both the ligation groups. The expressions of CD11b, GFAP, IL-1β and TNF-α in the two ligation groups were similar and all significantly higher than those in the control group ( < 0.05). IL-6 mRNA level was significantly higher in chromic catgut group than in the silk suture group ( < 0.05).@*CONCLUSIONS@#The CCI models established by partial sciatic nerve ligation with silk suture and chromic catgut all show glial activation, and the inflammatory response is stronger in chromic catgut group.

Clinical effect of modified skin traction in treating chronic skin ulcer / 中华整形外科杂志

Objective@#To explore the clinical effect of cotton pads under stitches when intradermal traction with sutures is used to repair of chronic wounds.@*Methods@#From January 2009 to August 2016, 21 patients with 31 wounds were treated by continuous intradermal traction. Wound edges were sutured with 2-0 silk thread in horizontal mattress fashion, but not tied. Then small cotton pads were put under stitches to protect the skin around the wound. After that, the sutures on both sides of the wound edges were pulled to the center of the wound with a certain force. And the wound was sutured finally when the skin on both sides of the wound was closed enough.@*Results@#All of 31 wounds healed without necrosis of the skin margin and 5 cases of lacerated wound caused by silk thread healed after dressing change. The healing time was (43.24±11.46) days, and there was scarcely hypertrophic scar at the stitches. This method was compared with the previous method of protecting stitches with silicone tubes( referring to past data). There was no significant difference in the healing time between the two methods (P=0.119), and less laceration occurred under the stitches with cotton pads (P=0.046).@*Conclusions@#It is a commendable method for treating chronic wounds to put cotton pads under the stitches while tracting the wound edges with sutures. It can effectively cushion the cutting force of the silk thread, protect the traction point and facilitate the replacement of the pads.

The Effect of Indwelling Silk Suture Following Aspiration in the Treatment of Chronic Lateral Malleolar Bursitis / 대한족부족관절학회지

PURPOSE: To evaluate the drainage effect of silk suture following aspiration of the bursa as an early treatment of chronic lateral malleolar bursitis MATERIALS AND METHODS: Thirteen cases, which have over two weeks of history and over one year of follow-up, were investigated. The average duration of follow-up was 16.4 months. The average symptom duration before introduction into this study was 7.8 weeks. With an aseptic technique, the aspiration of the bursa was done with 18G needle and syringe and then the insertion of silk suture through the aspiration needle was performed. The amount of drainage was identified two or three times in a week and stitch out was done at the cessation of drainage. Over one year follow-up, recurrence, infection, pain, and limitation of range of motion were investigated by telephone interview. RESULTS: Redness around the insertion site of silk suture was found in all cases, but there was no development of active infection or recurrence. The average duration of treatment is 10.4 days. CONCLUSION: The drainage with silk suture following aspiration of the bursa is less invasive and very effective method in the early treatment of chronic lateral malleolar bursitis.

The Effect of Indwelling Silk Suture Following Aspiration in the Treatment of Chronic Lateral Malleolar Bursitis / 대한족부족관절학회지

PURPOSE: To evaluate the drainage effect of silk suture following aspiration of the bursa as an early treatment of chronic lateral malleolar bursitis MATERIALS AND METHODS: Thirteen cases, which have over two weeks of history and over one year of follow-up, were investigated. The average duration of follow-up was 16.4 months. The average symptom duration before introduction into this study was 7.8 weeks. With an aseptic technique, the aspiration of the bursa was done with 18G needle and syringe and then the insertion of silk suture through the aspiration needle was performed. The amount of drainage was identified two or three times in a week and stitch out was done at the cessation of drainage. Over one year follow-up, recurrence, infection, pain, and limitation of range of motion were investigated by telephone interview. RESULTS: Redness around the insertion site of silk suture was found in all cases, but there was no development of active infection or recurrence. The average duration of treatment is 10.4 days. CONCLUSION: The drainage with silk suture following aspiration of the bursa is less invasive and very effective method in the early treatment of chronic lateral malleolar bursitis.

A report on 102 laparoscopic cholecystectomies using suture and knot instrument in the abdominal cavity / 中国微创外科杂志

Objective To evaluate the security and the reliability of ligating the cystic duct and the cystic ar- tery with common silk suture as the substitute for titanic or biological clamps in laparoscopic cholecystectomy (LC) us- ing the suture and knot instrument developed by the authors. Methods One hundred and two laparoscopic chole- cystectomies were performed by the authors using the instrument. Results All patients were discharged in the post- operative fourth or fifth day without any complication. Conclusion The instrument used for LC was safe and reliable.