Résumé
Objective @#To investigate the clinical effect of polidocanol sclerotherapy in the treatment of giant venular malformations of the lips and cheeks in adults.@*Methods@# From September 2019 to September 2020, 5 patients with huge venular malformations of the lips and cheeks (4 males, 1 female) admitted to Xuzhou Central Hospital were included in the study. All the patients were treated with local injection of polidocanol foam scleroagent, and all patients were followed up with a 3-week treatment course. If the clinical symptoms were not alleviated and the MRI examination showed that > 25% of the lesion remained, or it relapsed again after symptoms are stable, the patient needed to be treated again. The endpoints of treatment were: ①subsidence of clinical symptoms and MRI showing residual lesions < 25% in size; ②continuous treatment for 4 times without relief or aggravation of symptoms; ③a discontinuation of treatment. @* Results@#All 5 patients successfully completed the treatment and were injected 2 to 4 times during treatment. The curative effect was evaluated according to the Achauer standard, including grade Ⅰcurative effects in 1 patient, grade Ⅱ in 2 patients, grade Ⅲ in 2 patients. Among them, one patient suffered from erosion and bleeding in the lesion before the operation, and the symptoms were significantly improved postoperatively. No serious side effects were found except skin pigmentation in 1 case. @*Conclusion@#Local injection of polidocanol foam scleroagent is a safe and effective treatment method for adult giant venular malformations of the lips and cheeks, and it has a hemostatic effect on spontaneous bleeding invenular malformations.
Résumé
Objective: The effect of pingyangmycin(PYM) in treatment of venous-venular malformation(mixed hemangioma) of the children was evaluated. Methods: Three hundred and twenty-five(132 male patients,193 female patients) patients with venous-venular malformation in the facial-neck and limbs and body regions of the children between January 1998 and January 2005 were reviewed.Patients ages were between one month and 12 years.Among others ages of 175 patiets were ≤ 6 month(53.85%).Pingyangmycin was injected into the cavity or in the circumference of the venous-venular malformations,and the injected was repeated every 7-10 days.This process may be repeated 3-5 times. Results: Three hundred and twenty-five patients were followed up for 6 months-7 years.The cured was 162 cases((49.85%)),basically cured was 124 cases(38.15%),getting improvement was 10.46%.Cure and basically cure rate were 88.00%.The total efficiency was 98.46%. Conclusion: This method was a safe,simple and effective therapy for the venous-venular malformation in the facial-neck and body-limbs regions of the children.