Perfil epidemiológico de neoplasias epiteliales de glándulas salivales / Epithelial tumors of salivary glands: review of 286 pathology reports

Background:: Epithelial tumors of the salivary glands, including benign tumors and aggressive malignancies with different prognoses, are uncommon. Aim: To describe the frequency and distribution of salivary gland tumors according to age, gender and anatomical location. Material and Methods: Review of pathological reports of salivary gland tumors of a Pathology laboratory at a clinical hospital from 2006 to 2016. Results: Five hundred ninety salivary gland biopsies were reviewed. Of these, 286 (49%) were primary epithelial tumors of the salivary glands. Two hundred thirty (80%) were benign and 56 (20%) were malignant tumors. Regarding location, 274 (96%) were in the major salivary glands, and 12 (4%) in the minor salivary glands. The most common histological types were pleomorphic adenoma for benign tumors in 172 cases, followed by papillary cystadenoma lymphomatosum in 33 cases. Mucoepidermoid carcinoma was the most common malignant tumor in 14 cases. Conclusions: These results are similar to reports from abroad, however more studies are necessary to be able to establish a more representative and updated analysis.

Adenoma pleomórfico de vulva / Vulvar Pleomorphic Adenoma

El adenoma pleomórfico (AP) es el tumor benigno más prevalente de las glándulas salivales mayores; sin embargo, esta no es su localización anatómica exclusiva. Las células mioepiteliales, tapizan la membrana basal de las porciones terminales de diferentes tejidos glandulares exocrinos incluyendo los salivales, lacrimales, mamarios y sudoríparos; por esta razón, no es insólito que este tumor se origine en tejidos glandulares diferentes a los salivales. El adenoma pleomórfico de la vulva es un hallazgo infrecuente, con pocos casos reportados en la literatura, siendo este caso el primero reportado en Colombia y Latinoamérica(AU)

Pleomorphic Adenoma is the most prevalent benign tumor among the major salivary glands; nevertheless, this is not the exclusive anatomic localization. Myoepithelial cells cover the basal membrane of the terminal portions of different exocrine glandular tissues including the salivary glands, lacrimal glands, mammary tissue and sweat glands. Consequently, it is not rare that this kind tumor originate in tissues different from the salivary glands. The vulvar pleomorphic adenoma is an uncommon finding, with few reported cases in literature. Actuality this the first case reported in Colombia and Latin America(AU)

Minor intraoral salivary gland tumors: a clinical-pathological study / Neoplasias intraorais de glândula salivar menor: estudo clínico-patológico

ABSTRACT Objective To evaluate the clinical-pathological profile of patients with minor salivary gland neoplasms. Methods A retrospective study of specific cases diagnosed as benign and malignant tumors of the minor salivary glands was performed. The data were collected from medical records of patients seen at a hospital over a period of 15 years. The sample was made up of 37 cases. For the pathological study, slides containing 5μm thick sections stained with hematoxylin and eosin were used. The data were tabulated using descriptive statistics. Results Malignant neoplasms represented 70.3% of cases. The mucoepidermoid carcinoma was the most common neoplasm (45.9%), followed by pleomorphic adenoma (24.4%). Most patients were female (70.3%), aged between 71 and 80 years. The palate (67.6%) and the retromolar region (10.8%) were the most affected sites. Conclusion Mucoepidermoid carcinoma was the most common tumor in minor salivary glands. These tumors are more common in females aged over 40 years. The palate was the most common affected site.

RESUMO Objetivo Avaliar o perfil clínico-patológico de pacientes com neoplasias de glândula salivar menor. Métodos Foi realizado um estudo retrospectivo de casos específicos diagnosticados como neoplasias benignas ou malignas de glândula salivar menor. Os dados foram coletados dos prontuários dos pacientes atendidos em um hospital no período de 15 anos. A amostra final foi de 37 casos. Para o estudo histopatológico, foram usadas lâminas contendo secções com 5μm de espessura, coradas pela técnica de hematoxilina e eosina. Os dados foram tabulados de forma descritiva. Resultados As neoplasias malignas representaram 70,3% dos casos. O tipo histológico mais prevalente foi o carcinoma mucoepidermoide (45,9%), seguido do adenoma pleomórfico (24,4%). A maioria dos pacientes era do sexo feminino (70,3%), com idade entre 71 e 80 anos. O palato (67,6%) e a região retromolar (10,8%) foram os sítios mais acometidos. Conclusão O carcinoma mucoepidermoide foi o tumor mais comum das glândulas salivares menores. Estes tumores foram mais comuns em mulheres com mais de 40 anos. O palato foi o sítio mais acometido.

Siringoma Condroide. Presentación de un caso / Chondroid syringoma. Case presentation

Introducción: El Siringoma Condroide o tumor mixto es una neoplasia habitualmente benigna que constituye 0,01 por ciento de los tumores primarios de la piel. Es una entidad análoga al tumor mixto (Adenoma Pleomorfo) de glándulas salivales. El diagnóstico es exclusivamente histopatológico. Objetivo: Presentar una paciente con un diagnóstico poco común de Siringoma Condroide benigno, donde se destaca como diagnóstico diferencial entre los tumores de la piel en cabeza y cuello. Presentación de caso: Presentamos el caso de una paciente femenina, de 45 años de edad, quien acude a consulta por presentar un nódulo subcutáneo en la región geniana derecha, que apareció como un pequeño aumento de volumen debajo de la piel, que fue creciendo gradualmente, asintomático, redondeado, bien delimitado, móvil, de consistencia entre suave y firme, de varios meses de evolución, como única lesión. Clínicamente se interpretó como un quiste epidérmico. Su diagnóstico anatomopatológico fue el de Siringoma Condroide benigno o Tumor mixto de la piel. Conclusiones: Resulta un caso interesante debido a la baja frecuencia de presentación de esta lesión. Es importante tener presente esta entidad en el diagnóstico diferencial de los tumores de la piel en cabeza y cuello. A pesar de ser un tumor benigno es necesario el seguimiento del paciente, pues, aunque es muy raro, se han descrito casos con un comportamiento maligno(AU)

Introduction: Chondroid syringoma or mixed tumour is usually a benign neoplasia, constituting 0.01 percent of primary tumours of the skin. This is analogous to mixed tumour (Pleomorphic adenoma) of salivary gland. The diagnosis is only histopathologically. Objective: To present a patient with a diagnosis not very common of chondroid syringoma, where it is highlighted as differential diagnosis among the head and neck skin tumours. Case presentation: Is presented a case of a female patient; 45 years old, that arrived to the consulting room showing a subcutaneous nodule on the right genial region, it appeared as an asymptomatic slow-growing small mass, rounded, well bounded, mobile of soft and firm consistence, of several months of evolution, as a single lesion. The diagnosis was a chondroid syringoma or skin mixed tumour. Conclusions: It is an interesting case because it has a low frequency. It is important bear in mind this entity in the differential diagnosis of head and neck skin tumours. Despite being a benign tumour it is necessary to monitor patients, because even though it is uncommon, some cases have been reported with a malignant behaviour(AU)

Clinicopathological analysis of salivary gland tumors over a 15-year period

Abstract Salivary gland tumors (SGT) are rare neoplasms that generate interest due to their histopathological diversity and clinical behavior. The aims of the present study were to investigate clinicopathological aspects of SGTs diagnosed at a tertiary health center and compare the findings with epidemiological data from different geographic locations. Cases of tumor in the head and neck region at a single health center in the period between 1995 and 2010 were reviewed. Patient gender, age and ethnic group as well as anatomic location, histological type and clinical behavior of the tumor were recorded. Availability of complete information about these aspects was considered the inclusion criteria. Descriptive statistical analysis of the data was performed using the frequencies of categorical variables. Among the 2168 cases of tumors in the head and neck region, 243 (11.20%) cases were diagnosed in the salivary glands, 109 of which met the inclusion criteria: 85 (78%) benign tumors and 24 (22%) malignant tumors. Mean patient age was 46.47 years. The female gender accounted for 56 cases (51.4%) and the male gender accounted for 53 (48.3%). The major salivary glands were affected more (75.2%) than the minor glands. The most frequent benign and malignant SGTs were pleomorphic adenoma (81.2%) and adenoid cystic carcinoma (58.3%), respectively. In conclusion, pleomorphic adenoma and adenoid cystic carcinoma are the most frequent benign and malignant lesions, respectively. Comparing the present data with previous studies on SGTs, one may infer that some demographic characteristics and the predominance of malignant tumors vary in different geographic regions.

Pleomorphic Adenoma of Hard Palate: A Case Report and Review of Literature.

Pleomorphic adenoma is a benign mixed tumor, which is composed of myoepithelial and epithelial cells. A fibrous capsule separates these cells from the surrounding tissues. Pleomorphic adenoma has unusual histopathologic features. It is the most common benign tumor affecting both major and minor salivary glands. Parotid salivary gland is affected mostly in the major group, and palate is the most common site affected in minor salivary glands. The upper lip is the second most common site followed by buccal mucosa. Less than 3% of the salivary gland tumors account for head and neck tumors. In few cases, benign pleomorphic adenoma may turn malignant also. In this case report, a female patient aged 32 years who reported with a complaint of painless swelling in the palate is presented.

Study of Salivary Gland Neoplasms.

Tumors of the salivary glands are uncommon and they present a great variety of histological types with many structural variation. They have a low incidence and their anatomical relationship especially that of the parotid gland to the facial nerve make their management challenging. The present study was carried out to find out the prevalence of salivary gland neoplasms, to see associated conditions like sialadenitis, sialolithiasis coexisting with salivary gland neoplasms and to do cytohistopathological correlation. Total 96 cases were collected of which 66.7% were benign and 33.3% were malignant. In 81 (84.3%) cases tumors occurred in major salivary gland while 15 (15.6%) cases in minor salivary gland. Among major salivary gland, parotid was the commonest site and in minor salivary glands, palate was the commonest site followed by lips. Pleomorphic adenoma was the commonest benign tumor and adenoid cystic carcinoma was the commonest malignant tumor followed by mucoepidermoid tumor. There was one case of synovial sarcoma. Associated pathology like sialadenitis and sialolithiasis were present in 16 benign and 5 malignant tumors. Cytohistocorrelation was seen in 63 out of 64 (98.4%) benign and 16 out of 18 (88.8%) malignant tumors.

Pleomorphic Adenoma in Cheek: An Uncommon Finding.

Pleomorphic adenoma (PA), also called benign mixed tumor, is the most common benign salivary gland neoplasm. About 90% of these tumors occur in the parotid gland and 10% in the minor salivary glands. Review of literature, clinical features, pathology, radiological fi ndings, and treatment of these tumors are discussed. We report a case of PA of minor salivary gland of cheek in 16-year-old female patient.

Adenoma pleomorfo del paladar: reporte de un caso y revisión de la literatura / Pleomorphic adenoma of the palate: report of a case and review of the literature

El adenoma pleomorfo es el tumor benigno más frecuente de lasglándulas salivales. Su localización principalmente es en la glándula parótida, pero cuando aparece en una glándula salival menor, el paladar es su localización más común. Presenta un crecimiento lento y continuo; clínicamente se presenta como un nódulo o tumor asintomático, firme y bien delimitado. El diagnóstico se realiza mediante biopsia por aspiración con aguja fi na o biopsia escisional de la lesión, siendo de gran importancia debido a que a pesar de ser una tumoración benigna, en ocasiones puede presentar transformación maligna. El tratamiento consiste en la exéresis completa de la lesión con márgenes sanos. Se presenta el caso de un paciente masculino de 40 años, con una masa en el paladar duro y blando de seis años de evolución. Tras la exéresiscompleta de la lesión, el estudio histopatológico confirmó el diagnósticode adenoma pleomorfo

Pleomorphic adenomas are the most common benign tumor of the minor salivary glands. They are primarily found in the parotid gland, except when they appear in a minor salivary gland, in which case the palate is the most common site. They display a slow, steady growth. Clinically the adenoma appears as a fi rm, well-defi ned, asymptomatic nodule or tumor. Diagnosis is confi rmed by means of fi ne-needle aspiration biopsy or excisional biopsy of the lesion. It is extremely important that they are tested given that, despite their being a benign tumor, they can sometimes become malignant. Treatment consists of the complete excision of the lesion with clean surgical margins. We report the case of a 40-year-old male patient with a mass in the hard and soft palate that had evolved over a period of six years. Following the complete excision of the le-sion, histopathology confi rmed the diagnosis of pleomorphic adenoma.

Pleomorphic Adenoma Lacrimal Gland.

Pleomorphic adenoma is the most common epithelial tumour of the lacrimal gland1. Histological confirmation is necessary for diagnosis. I report a case of pleomorphic adenoma in an otherwise well 39 year old female patient and review the clinical and histological features of this tumour. These lesions are usually cured by simple surgical excision3, Inadequate removal leads to recurrence6. The incidence of pleomorphic adenoma is 3.4 to 4.8 % of the orbital lesions5.

Incidencia de los tumores de glándulas salivales: estudio retrospectivo de 78 casos / The incidence of salivary gland tumors: a retrospetive study on 78 cases

Los tumores de glándulas salivales son poco frecuentes y presentan características microscópicas complejas. Estos comprenden menos del 3 por ciento de todas las neoplasias de la región de cabeza y cuello. Se reportan en la literatura distintas incidencias en los tumores de glándulas salivales. El presente estudio fue llevado a cabo en el Servidio de Cirugía Maxilofacial, con conjunto con el Servicio de Anatomía Patológica del Hospital Zonal Mariano y Luciano de la Vega, Moreno, Buenos Aires, Argentina. El objetivo del mismo fue conocer la incidencia de los tumores, distinción por sexo y edad de los pacientes. Se analizaron 78 casos de tumores en glándulas salivales mayores (parótida, submaxilar y sublingual) y glándulas salivales menores. La mayor frecuencia de aparición la encontramos en glándulas salivales menores (46.2) 36 pacientes, seguido por la localización en gla´dnula salival (37, 1) 29 pacientes y luego en glándula submaxilar (16, 7) 13 pacientes. El adenoma pleomorfo fue el tumor más frecuentemente hallado, representando 55.1 por ciento de todos los casos, seguido por el tumor de Whartin, 12,8 por ciento y el carcinoma mucoepidermoide 8,9 por ciento.

Lesiones intraorales de glándulas salivales menores / Intraoral lesions of minor salivary glands: analysis of 59 patients

Background: Most salivary gland lesions are benign. Tumors are uncommon. Pleomorphic adenoma and cystic adenoid carcinoma are the most common benign and malignant lesions. Aim: To assess the incidence management and evolution of intraoral lesions among patients consulting in a head and neck surgical service. Material and Methods: Retrospective review of medical records of patients consulting for intraoral lesions of minor salivary glands between 1975 and 2009 in a head and neck surgical service. Results: Thirty five females and 24 males are reported. Forty eight (81 percent) had benign lesions. Of these, 35 (73 percent). were non neoplastic lesions. Eleven patients had malignant lesions. Of these, four (36 percent) had a mucoepidermoid carcinoma, two (18 percent) had an adenoid-cystic carcinoma, two (18 percent) had an acinous cell carcinoma and one patient each had an undifferentiated carcinoma, an adenocarcinoma and an epidermoid carcinoma. Conclusions: In this series of patients, benign lesions predominated. Benign lesions were excised and the management of malignant lesions depended on the type of tumor.

Introducción: Las lesiones de glándulas salivales menores son en su mayoría benignas. Los tumores son infrecuentes y conforman un grupo heterogéneo, siendo el adenoma pleomorfo la neoplasia benigna más frecuente y el carcinoma adenoideo-quístico el tumor maligno más encontrado. Objetivos: El propósito de este estudio es evaluar la incidencia, manejo y evolución de las lesiones intraorales de glándulas salivales menores en el Servicio de Cirugía de Cabeza y Cuello del Hospital Barros Luco-Trudeau. Material y Método: Se presenta estudio retrospectivo de 59 casos tratados entre 1975 y 2009 en dicho hospital. Resultados: Encontramos 35 mujeres y 24 hombres. En 48 pacientes (81,3 por ciento) se encontró lesiones benignas, de las cuales 35 (73 por ciento) correspondieron a lesiones no neoplásicas y 13 (27 por ciento) a neoplasias. Las neoplasias malignas fueron 11 (18,6 por ciento del total), 4 (36,3 por ciento) con Ca mucoepidermoide, 2 (18 por ciento) con Ca adenoideo-quístico, 2 (18 por ciento) con Ca de células acinosas, 1 (9 por ciento) con Ca indiferenciado, 1 (9 por ciento) con adenocarcinoma y 1 (9 por ciento) con Ca epidermoide. Conclusiones: Las lesiones de glándulas salivales menores en nuestro hospital se caracterizan por ser predominantemente benignas. Se encontró similar frecuencia de tumores benignos y malignos. Predominó el adenoma pleomorfo entre los primeros y el carcinoma mucoepidermoide entre los segundos. Los tumores benignos, luego de su extirpación, se manejaron con cierre del lecho tumoral mediante rotación de colgajos locales de mucosa oral para cobertura y, en algunos casos, cierre por segunda intención. La evolución fue en general excelente. En el caso de los tumores malignos, el manejo dependió de Ia histología.

clinico-pathologic study of 82 intraoral minor salivary gland tumors

Intraoral minor salivary glands tumors [MSGT] are uncommon, with geographic variations in frequency and distribution. This study analyzed the clinic-pathologic features of these tumors in Shiraz, southern Iran. All of cases histopathologically recorded as epithelial MSGT in Pathology Department of Khalili Hospital from 2002 to 2009 were evaluated with regard to patient's age and gender, tumor location and type, retrospectively. Out of 82 cases of MSGT, 53.7% were benign and 46.3% were malignant. Pleomorphic adenoma and adenoid cystic carcinoma were the most common benign and malignant tumors, respectively. The palate was the most common site of involvement [64.6%]. Male to female ratio was 1:1.27. The mean age of the patients was 35.0 +/- 17.2 years for benign and 48.8 +/- 18.2 years for malignant tumors. MSGTs in the present study represent many characteristics of other studies. However, our patients who were affected by benign tumors were young

Adenoma pleomorfo con localización atípica: presentación de un caso clínico en trígono retromolar / Pleomorphic adenoma with atypical location: report of a clinical case in the retromolar area

Las neoplasias de las glándulas salivales constituyen aproximadamente el 3 por ciento de todos los tumores de cabeza y cuello. La neoplasia más frecuente que involucra tanto a las glándulas salivales mayores como menores es el adenoma pleomorfo. Se presenta con mayor frecuencia en las glándulas parótidas. En glándulas salivales menores, el paladar es el sitio de elección. Es un tumor indoloro, de crecimiento lento. El rango de edad de aparición es entre los 30 y 50 años y es más frecuente en el sexo femenino que el masculino con una relación de 2 a 1. Presentamos un caso clínico de muy baja frecuencia de aparición en cuanto a la localización, en un paciente de sexo femenino de 67 años de edad a la que se le diagnosticó adenoma pleomorfo en la región del trígono retromolar.

Laterality of pleomorphic adenoma of parotid gland

Although pleomorphic adenoma is the commonest benign tumor of both major and minor salivary glands, yet it bears certain peculiar characters like invariable growth rate, short spells of spurts of growth, long quiescent periods, invasion of surrounding tissues by its capsular projections, recurrence, notorious for implantation and classic origin from the tail of parotid gland. Since the nerve of facial expression [facial nerve] falls within the domain of otolaryngologists but its course along with its variable branches through the parotid gland has always remained an area of common interest between general and ENT surgeons. With the more and more involvement of E.N.T. surgeons in head and neck oncology, the cancer of salivary glands looks to be being taken over by them in recent decades. FNAC inspite of its accuracy is loosing its superiority over modern ultrasonography. This is an observational study. This study was carried out in Combined Military Hospital Lahore from Feb 2005 to Feb 2008. A total of 28 patients with unilateral mass of parotid gland, all with FNAC [Fine needle aspiration cytology] positive for pleomorphic adenoma were included in the study without any discrimination of age, sex or size of tumor. Each patient underwent CT scan and surgical modality of treatment was selected for every patient with post-operative histopathology study to confirm or otherwise of FNAC diagnosis. Female male ratio was 3:4, mean age in males was 44, in females was 37. Histopathology-disproved FNAC in 7.14%. Ratio between involvement of superficial lobe and both lobes was 13:1. Post-operative transient facial nerve paresis was seen in 12 out of 28 patients and there was surprising laterality of right parotid involvement, ratio between right and left parotid being 11:3. Smallest tumor at presentation was 3x3 centimeter and largest was 14x10 centimeter in size. Markedly more incidence of pleomorphic adenoma on right side of face is observed. It has not been reported previously. Zero percent facial nerve severance in 28 parotidectomies reflects vigilance and surgical skill of today's otorhinolaryngologists

Estudo clinicopatológico de 106 adenomas pleomórficos de glândula salivar maior / A clinicopathologic study of 106 pleomorphic adenomas of the major salivary glands

INTRODUÇÃO: O adenoma pleomórfico (AP) é o mais comum dos tumores das glândulas salivares. Transformação maligna pode ocorrer após recorrências ou em casos com longo tempo de evolução. OBJETIVO: Analisar os aspectos clinicoepidemiológicos e anatomopatológicos do AP de glândula salivar maior, principalmente os considerados indício de transformação maligna. MATERIAL E MÉTODO: Foram avaliados 106 casos de AP pela pesquisa retrospectiva nos prontuários clínicos e revisão das preparações histológicas. RESULTADOS: A média de idade dos pacientes foi de 39,51 anos, houve predomínio do sexo feminino (69,5 por cento), a glândula parótida foi a mais acometida (86,8 por cento) e o tempo de evolução foi superior a um ano em 76,74 por cento dos casos, com tamanho tumoral de 3,48 cm em média. A avaliação histopatológica demonstrou cápsula tumoral incompleta e delgada em 49 por cento dos casos. Protrusões para a cápsula ou extensão extracapsular foram infreqüentes, 11,32 por cento e 8,49 por cento, respectivamente. A matriz extracelular variou entre mixocondróide (41,5 por cento), mixóide (36,8 por cento), condróide (3,8 por cento) e fibrótica (1,9 por cento), tendo sido observadas associações entre os diversos tipos. O componente epitelial/mioepitelial constituiu 50 por cento ou mais do tumor em 65,1 por cento dos casos e estava disposto em arranjos cordonal (86,8 por cento), ductal (81,1 por cento), sólido (40,6 por cento), cístico (20,7 por cento) e em "paliçada" (8,49 por cento). Metaplasia escamosa ocorreu em 16,04 por cento dos casos. Alterações histopatológicas relacionadas com transformação maligna foram incomuns: hialinização extensa (4,7 por cento) e necrose (0,9 por cento). CONCLUSÕES: confirma-se a diversidade histopatológica do AP. Características associadas a transformação maligna não foram freqüentes na amostra.

INTRODUCTION: Pleomorphic adenomas (PA) are the most common histologic type of salivary gland tumors. Malignant transformation may occur in the setting of recurrent or longstanding disease. OBJECTIVE: Evaluate the clinicopathologic characteristics of PA of the major salivary glands, particularly tumors showing signs of malignant transformation. MATERIAL AND METHODS: The clinical and histopathologic characteristics of 106 cases of PA were evaluated retrospectively. RESULTS: The mean patient age was 39.5 years. There was a predominance of female patients (69.5 percent). The parotid was the most commonly affected gland (86.8 percent). The tumor had been present for over a year in 76.74 percent of the cases, with a mean size of 3.48 cm. Histologic examination revealed a thin and incomplete capsule in 49 percent of the cases; however, protrusions into the capsule or extracapsular extension were infrequent (11.32 percent and 8.49 percent, respectively). The extracellular matrix varied from myxochondroid (41.5 percent), myxoid (36.8 percent), chondroid (3.8 percent) and fibrotic (1.9 percent); coexisting patterns were observed. The myoepithelial-epithelial component corresponded to 50 percent or more of the tumor in 65.1 percent of the cases, and was solid (40.6 percent), cystic (20.7 percent), arranged in cords (86.8 percent), ducts (81.1 percent) and had a palisading configuration (8.49 percent). Squamous metaplasia was present in 16.04 percent of the cases. Features associated with malignant transformation were incommon: extensive hyalinization (4,7 percent) and necrosis (0,9 percent). CONCLUSION: The histopathologic diversity of PA was confirmed. Features associated to malignant transformation were unfrequent.

Perfil epidemiológico das neoplasias de glândulas salivares: análise de 245 casos

OBJETIVO: este trabalho tem por objetivo determinar a freqüência relativa e a distribuição das neoplasias epiteliais benignas e malignas de glândulas salivares. FORMA DE ESTUDO: Coorte histórica. MATERIAL E MÉTODO: registradas no Laboratório de Patologia e Citologia, em Aracaju-SE, no período de janeiro de 1980 a dezembro de 1999, considerando-se as variáveis sexo, idade, tipo racial, localização anatômica e diagnóstico histopatológico. RESULTADO: Dos 162.312 casos registrados, 245 (0,15 por cento) foram de neoplasias epiteliais de glândulas salivares, sendo 187 de natureza benigna (76,33 por cento) e 58 (23,67 por cento) malignas. O adenoma pleomórfico foi o tumor benigno mais identificado (89,94 por cento) e o carcinoma adenóide cístico foi o representante maligno mais prevalente (22,41 por cento). As neoplasias benignas ocorreram principalmente entre as 2° e 3° décadas de vida, exibindo predileção pelo sexo feminino, enquanto as malignas foram diagnosticadas entre as 6° e 7° décadas de vida, sendo as mulheres o principal alvo. CONCLUSÃO: Constatou-se que o padrão epidemiológico das neoplasias estudadas está em consonância com a maioria da literatura pesquisada.

Adénome pléomorphe de la parotide en ORL au CNHU de Cotonou (1985-2004)

Du 1er Janvier 1978 au 30 Juin 2004 soit en 26 ans 6 mois; 47 cas d'adenome pleomorphe histologi-quement confirmes de la parotide ont ete recus et traites en ORL au CNHU de Cotonou sur un total de 93 tumeurs parotidiennes toutes varietes histopathologiques confondues. 57;4des sujets ont ete de sexe feminin contre 42;6pour le sexe masculin. Les sujets ages de 15 a 50 ans ont represente 93;6de la serie. Le delai moyen avant la 1ere consultation a ete de 5 ans avec pour principal motif la gene esthetique : 91;5. Le volume de la tumeur a ete de 4 a 6 centimetres dans 83. Cette tumeur a ete sans adenopathie dans 97;7et sans paralysie faciale initiale dans 100des cas

Adénome pléomorphe de la parotide en ORL au CNHU de Cotonou (1985-2004)

Du 1er Janvier 1978 au 30 Juin 2004 soit en 26 ans 6 mois; 47 cas d'adenome pleomorphe histologi-quement confirmes de la parotide ont ete recus et traites en ORL au CNHU de Cotonou sur un total de 93 tumeurs parotidiennes toutes varietes histopathologiques confondues. 57;4des sujets ont ete de sexe feminin contre 42;6pour le sexe masculin. Les sujets ages de 15 a 50 ans ont represente 93;6de la serie. Le delai moyen avant la 1ere consultation a ete de 5 ans avec pour principal motif la gene esthetique : 91;5. Le volume de la tumeur a ete de 4 a 6 centimetres dans 83. Cette tumeur a ete sans adenopathie dans 97;7et sans paralysie faciale initiale dans 100 des cas