Research progress of allogeneic abdominal wall transplantation / 中国修复重建外科杂志

OBJECTIVE@#To summarize the research progress of surgical technique and immunosuppressive regimen of abdominal wall vascularized composite allograft transplantation in animals and clinical practice.@*METHODS@#The literature on abdominal wall transplantation at home and abroad in recent years was extensively reviewed and analyzed.@*RESULTS@#This review includes animal and clinical studies. In animal studies, partial or total full-thickness abdominal wall transplantation models have been successfully established by researchers. Also, the use of thoracolumbar nerves has been described as an important method for functional reconstruction and prevention of long-term muscle atrophy in allogeneic abdominal wall transplantation. In clinical studies, researchers have utilized four revascularization techniques to perform abdominal wall transplantation, which has a high survival rate and a low incidence of complications.@*CONCLUSION@#Abdominal wall allotransplantation is a critical reconstructive option for the difficulty closure of complex abdominal wall defects. Realizing the recanalization of the nerve in transplanted abdominal wall to the recipient is very important for the functional recovery of the allograft. The developments of similar research are beneficial for the progress of abdominal wall allotransplantation.

Alotransplante de pele como alternativa para o tratamento da queimadura dolorosa da criança / Allograft skin as an alternative for the treatment of the painful burn in children

Queimaduras de segundo grau são especialmente dolorosas em crianças. A cada dia que passa, a pele queimada tende a cicatrizar, mas há momentos em que a área lesada fica pior devido a curativos inadequados ou à infecção. A utilização de substitutivos dérmicos deve ser considerada. Relatamos a utilização de aloenxerto de pele como um substitutivo dérmico transitório, a fim de diminuir a dor e promover a reepitelização em queimaduras dolorosas de segundo grau. A redução da dor foi completa após o uso do aloenxerto de pele. A criança obteve reepitelização completa da área lesada, não necessitando de internação e enxerto autólogo. Aloenxertos podem representar uma possibilidade de cobertura temporária para queimaduras dolorosas de segundo grau em crianças.

Second-degree burns are especially painful in children. With each passing day, the burned skin tends to heal, but there are times when the injured area gets worst due to inadequate dressing or infection. The use of dermal substitutes must be considered. We report the use of skin allograft as a transitory dermal substitute in order to decrease pain and promote re-epithelialization in painful second-degree burns. The child got complete re-epithelialization of the injured area, not requiring hospitalization and skin grafts. The pain reduction was complete after using skin allograft. Allografts may represent a possibility of temporary coverage in painful second-degree burns in children.