Reportes y series de casos en patología: una mirada más allá de la H&E / Reports and case series on pathology: a look beyond the H & E

Los primeros reportes y series de casos en patología aparecen en la medicina egipcia en los papiros de Edwin Smith (siglo 17 AC) y de Ebers (alrededor de 1550 AC). Desde aquellos tiempos pasando por Hipócrates, Aristóteles, Avicena, Harvey, Morgani y Virchow, entre otros ilustres médicos, el patólogo ha descrito sus observaciones a través de reportes y series de casos. Esta contribución científica ha sido fundamental en el desarrollo de la medicina moderna y de la investigación básica aplicada a la clínica A lo largo del tiempo estas publicaciones han sido y serán una fuente de educación para informar enfermedades nuevas o reclasificar entidades previamente descritas en términos de nuevas clasificaciones, las cuales han cambiado basadas en el comportamiento biológico o en nuevos hallazgos de la biología molecular o la genética. El objetivo de estos estudios es comunicar sobre la evaluación, el diagnóstico, el tratamiento y el pronóstico de las enfermedades, e incluso mejorar muchos aspectos de la educación médica. Por definición los reportes y series de casos se encuentran dentro de los estudios observacionales y descriptivos. Para definir uno como serie de casos tiene que incluir más de 6 pacientes, es decir que con 5 menos se clasifica como artículo de reporte de casos. Se ha propuesto diferentes niveles de evidencia de la literatura médica enfocado a patología.

Los orígenes de la Sociedad de Anatomía Normal y Patológica de Chile / The origins of the Society of Normal and Pathological Anatomy of Chile

Desde los inicios, anatomistas y patólogos se unen en el año 1938 creando la Sociedad de Anatomía Normal y Patológica, con el fin de estimular sus investigaciones, buscar relacionarse tempranamente con morfólogos del resto de América y potenciar sus publicaciones en los Archivos Chilenos de Morfología. Es así como morfólogos chilenos provenientes de las principales Universidades del país participan por primera vez en Congresos y Jornadas tanto nacionales como internacionales. Quizás el trabajo en común con los cadáveres fue un punto fundamental en sus inicios, más el avance de los conocimientos en cada una de estas disciplinas y diferencias políticas posteriores serían dos hechos que explicarían que se separasen posteriormente en el año 1970. Sería por tanto, el primer esfuerzo de reunirse en torno a una Sociedad de Morfólogos en Chile, la base para la futura Sociedad Chilena de Anatomía.

From the beginnings, anatomists and pathologists are united in the year 1938 creating the Society of Normal and Pathological AnatomyChilean in order to stimulate their investigations, seek to relate early with morphologists of the rest of America and to promote their publications in the Chilean Archives of Morphology. This is how Chilean morphologists participate for the first time in national and international congresses and conferences from the main universities in the country. Perhaps the work in common with the corpses was a fundamental point in its beginnings, more, the advance of the knowledge in each of these disciplines and later political differences would be two facts that would explain that they separated later in the year 1970. It would be therefore The first effort to gather around a Society of morphologists in Chile, would be the basis for the future Chilean Society of Anatomy.

Charcot's skepticism / O ceticismo de Charcot

This paper brings a short review about a peculiar characteristic of Professor Charcot, the father of neurology: the skepticism, emphasizing his personal view regarding the prognosis of several neurological conditions.

Este artigo traz uma revisão acerca de uma característica peculiar do professor Charcot, pai da neurologia: o ceticismo, enfatizando a sua visão pessoal sobre o prognóstico de diversas doenças neurológicas.

El nacimiento de la patología y su desarrollo en la región / The birth of the pathology and its development in the region

Se presenta una rápida visión del surgimiento de los conceptos relacionados con la patología desde los tiempos de los griegos y los romanos hasta llegar al nacimiento de la disciplina con los aportes de Xavier Bichat. En relación al nacimiento de la disciplina en Colombia se narran sus inicios y las contribuciones del Doctor Alfredo Correa Henao.

It is presente and overview of the emergence of concepts related to the pathology since the time of the Greeks and Romans up to the birth of the discipline with the contributions from Xavier Bichat. In relation to the birth of the discipline in Colombia is described their development and the contributions of Dr. Alfredo Correa Henao.

Anatomistas y cirujanos de la Cátedra de Anatomía Normal, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba / Anatomists and surgeons of the Chair of Normal Anatomy, Faculty of Medical Sciences, National University of Córdoba

Conferencia presentada en el marco del 2do Congreso Nacional de la Asociación de Anatomistas de Córdoba (ADACO), y el 1er Encuentro latinoamericano de Anatomistas y el 1er Encuentro Latinoamericano de Histólogos y Embriólogos. El autor hace un breve reseña histórica de los anatomistas y cirujános de la Cátedra de Anatomía Normal perteneciente a la Facultad de Ciencias Médicas Córdoba, Argentina.

Paper presented as part of the 2nd National Congress of the Association of Anatomists of Córdoba (ADACO), and the 1st Latin American Meeting of Anatomists and the 1st Latin American Meeting and Embryologists Histologists. The author makes a brief history of anatomists and surgeons of the Chair of Normal Anatomy belonging to the Faculty of Medical Sciences Córdoba, Argentina.

Uma brasiliana médica: o Brasil Central na expedição científica de Arthur Neiva e Belisário Penna e na viagem ao Tocantins de Julio Paternostro / A Brazilian medical collection: Central Brazil in Arthur Neiva and Belisário Penna's scientific expedition and Julio Paternostro's voyage to Tocantins

Aborda o papel das viagens científicas realizadas por médicos, durante a primeira metade do século XX, na imaginação social sobre o Brasil. Com esse objetivo, são analisados dois textos: o relatório de Arthur Neiva e Belisário Penna, publicado em Memórias do Instituto Oswaldo Cruz, e o de Julio Paternostro, que veio a público em 1945 no livro Viagem ao Tocantins. O primeiro contribuiu para que se apontasse a patologia como marca definidora da identidade nacional durante a Primeira República (1899-1930). Esse fato teria repercussões nas décadas seguintes, como se verificou com relação ao livro de Paternostro, apresentado na época de sua publicação como obra de denúncia dos problemas nacionais. Além das doenças, a distância não apenas geográfica, mas sobretudo cultural entre litoral e sertão são os atributos ressaltados nesses retratos do Brasil.

The article addresses the role played within the social imaginary of Brazil by the scientific voyages of physicians in the first half of the twentieth century. Two texts are analyzed: a report by Arthur Neiva and Belisário Penna published in Memórias do Instituto Oswaldo Cruz and another, by Julio Paternostro, released in 1945 in Viagem ao Tocantins. The former contributed to singling out pathology as the defining mark of national identity during the First Republic (1899-1930), a fact that had repercussions in the following decades, as apparent in Paternostro's book, which at the time of its publication was presented as an indictment of national problems. These portraits of Brazil highlight as attributes of the country not only disease but also the geographic and, primarily, cultural distance separating the coast from the sertão.

Fritz Koeberle: visão da ciência pelo microscópio / Fritz Koeberle: vision of science microscope

Revisões históricas aos avanços científicos para o controle da doença, o Simpósio Internacional Comemorativo do Centenário da Descoberta da Doença de Chagas (1909-2009).

Semblanza del Profesor Benedicto Chuaqui Jahiatt a 5 años de su muerte (1934-2003) / A biographical sketch of Professor Benedicto Chuaqui, MD

The present article commemorates the fifth anniversary of the death of Professor Benedicto Chuaqui Jahiatt, a prominent Chilean pathologist at the School of Medicine ofthe Pontificia Universidad Católica de Chile. Professor Chuaqui was well known for his teaching skills, his scientific work with international projections and his humanistic visión of medicine. His publications reflect, his wide spectrum and integrative visión of different disciplines ofboth naturalsciences and¡inguistics.

Quantitative pathology : historical background, clinical research and application of nuclear morphometry and dna image cytometry

Quantitative analysis of histo- and cytochemical components such as DNA, RNA or chromatin pattern on one hand (cytometry) and the quantitative analysis of geometric non-chemical cell and tissue components (morphometry and sterology) on the other, have developed somewhat independently. Today, many different techniques, such as morphometry, sterology, and static image and flow cytometry are well established and routinely used in diagnostic quantitative pathology. The potential significance of these techniques in the individualization of care in cancer patients include the objective distinction between benign, borderline and malignant lesions, objective grading of invasive tumours, prediction of prognosis, and therapy response

Luigi Bogliolo / Luigi Bogliolo

Registra-se, de forma sumária, a trajetória do notável patologista sardo Luigi Bogliolo, docente das Universidades de Sassari, Bari e Pisa, que, obrigado a emigrar para o Brasil em virtude de sua posição antifascista, criou em Belo Horizonte, a partir de 1944, na Faculdade de Medicina da UMG (depois UFMG), uma Escola de Patologia que se imporia, por seu alto nível, no cenário científico do pais adotivo.

The author presents a brief biography of Luigi Bogliolo, a sardinian pathologist who emigrated to Brasil during the World War II and created in Belo Horizonte (MG) an important School of Pathology.