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J Environ Biol ; 2008 Mar; 29(2): 147-9
Article de Anglais | IMSEAR | ID: sea-113533

RÉSUMÉ

Lead (Pb) is the most ancient poison known to man. In the present study, amount of accumulation of Pb in liver, kidney, ovary and testes of rain quail was studied using different doses of lead. Spectrophotometric analysis of heavy metal treated organs was carried out to determine the amount of metal accumulation in these organs. LD50 value was 4 ppm. Dose of lead was given in three ranges of low, medium and high. It was observed that testes (< or =6.8 x 10(-6)) mgkg(-1)day(-1) and ovary (< or =7.5 x 10(-6)) mgkg(-1)day(-1), accumulated low amount from different doses when given continuously for 21 days. In contrast to this, liver (< or =9.2 x 10(-6)) mgkg(-1)day(-1) and kidney (< or =9.3 x 10(-6)) mgkg(-1)day(-1) accumulated the maximum amount of metal when treated for the same number of days. This study is quite unique and astonishing as the period for intoxication is short (21 days) as compared to the long ones (91 days and above). Our results show that generally metal accumulation is highest in liver, while it is low in gonad.


Sujet(s)
Animaux , Relation dose-effet des médicaments , Femelle , Rein , Plomb/pharmacocinétique , Intoxication par le plomb/médecine vétérinaire , Foie , Mâle , Ovaire , Caille/physiologie , Polluants du sol/pharmacocinétique , Spectrophotométrie , Testicule , Facteurs temps , Distribution tissulaire , Tests de toxicité , Polluants chimiques de l'eau/pharmacocinétique
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