Nasal Mucoepidermoid Carcinoma after Radiotherapy: Case Report

Introduction Mucoepidermoid carcinoma (MEC) is a tumor originated from the epitheliumof the glandular excretory ducts and has highly variable biological potential. It is the most prevalent cancer of the salivary glands. The present report aims to describe a case of nasal mucoepidermoid carcinoma that developed after adjuvant radiotherapy (RT) treatment of a recurrent pituitary macroadenoma. Case Report Male patient, 62 years old, presented with recurrent nasal epistaxis on the right, associated with intense pulsatile headache, visual analogical scale (VAS) 10/10, with improvement only with the use of opioids andmorphine. After undergoing oncological screening and study by imaging exams, the presence of an expansive seal lesion with suprasellar extension was seen, involving the medial wall of the cavernous segment of the right carotid artery and the anterior cerebral artery, as well as the presence of a new expansive lesion in the right nasal cavity, with ethmoid bone invasion superiorly and medial orbit wall invasion laterally, compressing the ipsilateral optic nerve canal. Discussion Sinonasal neoplasms represent a small portion of all malignancies of the upper aerodigestive tract, accounting for<5% of these neoplasms. The development of MEC involves risk factors such as occupational issues, history of trauma and surgery involving the nasal area, and radiation exposure, as in previous RT. Conclusion Mucoepidermoid carcinoma is an uncommon neoplasia and can be associated with RT treatment, as used in cases of recurrent pituitary macroadenoma. In general, surgical resection to obtain free margins of neoplastic tissue is the aimed treatment, seeking better prognosis.

Carcinoma mucoepidermoide intraóseo en mandíbula: Reporte de caso y revisión de la literatura / Intraosseous mucoepidermoid carcinoma in mandible: Case report and literature review Intrao

Resumen Introdución: El carcinoma mucoepidermoide intraóseo es una neoplasia maligna muy rara de las glándulas salivales, posee la capacidad de desarrollarse en cualquier parte de la boca, siendo la zona de molares- premolares y ángulo mandibular los sitios más frecuentes de su hallazgo. Objetivo: Reportar el caso de un carcinoma mucoepidermoide intraóseo de bajo grado en mandíbula, de una paciente adulta mayor que fue diagnosticada en un Servicio de Cirugía Oral y Maxilofacial después de ser referida por un odontólogo particular general. Métodos: Se le realizo un examen clínico e indico la toma de radiografía panorámica, tomografía y biopsia incisional. Resultados: La biopsia dio como resultado carcinoma mucoepidermoide intraóseo y posteriormente fue transferida al Servicio de Oncología. Conclusión: El carcinoma mucoepidermoide intraóseo es una patología infrecuente, de pronóstico favorable cuando es detectado a tiempo y posee características similares a otras patologías no tan agresivas.

Abstract Introduction: Intraosseous mucoepidermoid carcinoma is a very rare malignant neoplasm of the salivary glands, it has the ability to develop in any part of the mouth, being the molar-premolar area and mandibular angle the most frequent sites of its finding. Objective: To report the case of a low grade intraosseous mucoepidermoid carcinoma in the jaw, in an older adult patient who was diagnosed in an Oral and Maxillofacial Surgery Service after being referred by a general private dentist. Methods: A clinical examination was carried out and indicated the taking of panoramic radiography, tomography and incisional biopsy. Results: The biopsy resulted in intraosseous mucoepidermoid carcinoma and was later transferred to the Oncology Service. Conclusion: Intraosseous mucoepidermoid carcinoma is an infrequent pathology, with a favorable prognosis when it is detected early and has similar characteristics to other not so aggressive pathologies.

Mucoepidermoid Carcinoma of Palate: A Case Report.

The most common types of salivary gland tumors are the pleomorphic adenoma and the mucoepidermoid carcinoma (MEC). MEC mainly occurs in the parotid gland; intraorally MEC appears as asymptomatic swellings in minor salivary glands, most commonly occurs on palate. It shows a variety of biological behaviors and variable natural history. Clinical, radiological and histopathological findings of palatal MEC in a young woman presented here. Surgical resection was done. Follow-up of one and half year did not show any recurrence.

Mucoepidermoid carcinoma of the lung--a case report.

Mucoepidermoid carcinoma is an uncommon primary lung tumor. Mucoepidermoid carcinomas have been reported in all age group and equally in both sexes. A case of mucoepidermoid carcinoma histologically confirmed by biopsy is reported here. The patient is a 15 years old male presented with cough and dyspnoea for 5 days. Chest roentgenography showed segmental consolidation of right lower lobe. Chest computed tomography revealed a soft tissue mass with calcification within the lumen of lower trachea in precarinal location. The patient underwent thoracotomy for endotracheal mass and resection was done. Following operation, the patient is symptom free and follow-up CT scan shows normal tracheal outline.

Solitary skull metastasis from mucoepidermoid mimicking a parotid tumour.

Metastatic parotid tumours in the skull are very rare. An interesting case of a mucoepidermoid parotid tumour metastasizing to the skull vault is described in a patient who had previously been operated for a pituitary adenoma 20 years back with no post operative radiotherapy; however, she required hormonal supplementation therapy. She underwent an operation for a parotid tumour 7 years ago and received postoperative radiotherapy for the parotid tumour away from the site of the skull metastases. No local recurrence of the parotid tumour was noted. The initial diagnosis was that of a solitary intradiploic meningioma. Interesting clinico-radiological findings are presented.