Histological and immunohistochemical study of the effect of aging and dietary restriction on rat testicular germ cells with special reference to apoptosis

This study was done to throw light on the effect of aging as well as dietary restriction on the microscopic structure of the testis. Germ cells apoptosis was also studied, as apoptosis in testicular germ cells is critical for spermatogenesis in mammals. Twenty male albino rats were used in this study. They were classified into four groups: Groups I and II consisted of 5 adult rats each, of 4-5 months of age weighing 120-150 g. Groups III and IV consisted of 5 senile rats each, of 18-24 months of age weighing 250-300 g. Groups I and III received free access to diet and water. Whereas, groups II and IV received only free access to water. Group I served as a control group. After four days, all animals were sacrificed, the testis were removed and processed for routine H and E, PAS and Feulgin reaction. The specimens were immune stained using anti Bclx protein. Statistical analysis was also done to evaluate the morphometric data. The results of the study are given

A propósito de un caso de tumor del seno endodermal del mediastino y breve revisión de la literatura / A case of endodermal sinue tumor at the mediastinum literature revision

El tumor del Seno Endodermal (TSE) es una neoplasia de las células germinales, de baja presentación en la población general y extraordinariamente rara en el compartimiento mediastinal. En el presente informe se hace referencia de un paciente de 20 años de edad que presentó TSE del mediastino anterior de grandes dimensiones, localmente avanzado y con comportamiento muy agresivo. El diagnóstico se estableció mediante biopsia intratorácica percutánea por aspiración y el paciente recibió quimioterapia combinada con plantino y eptopósido, falleciendo antes de completar el primer curso de tratamiento