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1.
J Environ Biol ; 2007 Oct; 28(4): 701-5
Article Dans Anglais | IMSEAR | ID: sea-113716

Résumé

This investigation was conducted in an area of oil spill along the east coast of Thailand to examine the relations among cytochrome P450 1A activity in liver and PAHs in the bile of the tonguefish and petroleum hydrocarbons in the sediments. PAH sediment concentrations in the reference and oil spill areas were 5.03 +/- 0.42 and 0.21 +/- 0.043 microg(-1) dry weight respectively Cytochrome activity in fish liver from oil spill area was 45.40 +/- 3.50 pmoles/ min/mg protein, almost threefold higher than that from the reference sites. Flourescense detection in bile metabolites at the oil spill area, 69.8 +/- 9.9 flourescense unit was significantly higher than that at the reference sites, 22.9 +/- 5.5 and 22.2 +/- 3.5 fluorescence unit. A strong correlation was found among cytochrome P450 1A activity in liver, PAH of bile metabolites and petroleum hydrocarbons. Both cytochrome and bile metabolites activity decreased seaward varying to the distance from the oil polluted area. We concluded that both detections in tonguefish can be regarded as a complementary biomarkers for the exposure of PAHs in tropical marine environments.


Sujets)
Animaux , Bile/composition chimique , Cytochrome P-450 enzyme system/métabolisme , Poissons , Sédiments géologiques/composition chimique , Foie/enzymologie , Pétrole/analyse , Composés polycycliques/analyse , Spectrométrie de fluorescence , Polluants chimiques de l'eau/analyse
2.
Indian J Exp Biol ; 1991 Jul; 29(7): 611-4
Article Dans Anglais | IMSEAR | ID: sea-56215

Résumé

South Indian food dishes, comprising several deep fried items have been proved to be mutagenic. Polycyclic aromatic hydrocarbons (PAHs) such as, benzo(a)pyrene, chrysene and dibenzanthracene, which are potent and proven carcinogens have been identified and quantified in several of the commonly consumed South Indian food dishes and food components. Most of the pyrolysed items contained PAHs in appreciable quantities. PAHs were detected in significant levels in salted, sundried and oil fried vegetables and fishes. Some of the raw and uncooked food components also revealed the presence of PAHs.


Sujets)
Animaux , Benzo[a]pyrène/analyse , Cancérogènes/analyse , Chrysènes/analyse , Pollution de l'environnement , Poissons , Analyse d'aliment , Contamination des aliments , Manipulation des aliments , Tumeurs gastro-intestinales/épidémiologie , Température élevée , Inde/épidémiologie , Mutagènes/analyse , Composés polycycliques/analyse , Légumes
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