Relevancia de las relaciones intrafamiliares en pacientes consumidores de heroína de la ciudad de Armenia / Relevance of intrafamily relations in heroin-consuming patients of the city of Armenia

Se propuso conocer la importancia de las relaciones intrafamiliares en consumidores de heroína, con una muestra de 10 heroinómanos que oscilan entre los 18 y 29 años de edad. Para ello se realiza un estudio cuantitativo-descriptivo de corte transversal con base a pacientes que asisten a consulta externa del Hospital Departamental Universitario del Quindío San Juan de Dios. Para tal fin, se utilizó una entrevista estructurada y el cuestionario de clima familiar de FES DE MOOS, que evalúan las relaciones interpersonales, aspectos de desarrollo y estructura básica. De acuerdo a los resultados obtenidos, el 100% coincide que la familia es el factor principal para recibir ayuda profesional; en cuanto a las subescalas los niveles más representativos fueron: conflicto (61.1), moralidad-religiosidad (55.5) y control (52.1).

It aimed to know the importance of intra-family relationships in heroin users, with a sample of 10 heroin addicts ranging between 18 and 29 years of age. For this quantitative study is performed descriptive cross-sectional basis to patients attending outpatient department of the Hospital Universitario del Quindío Departmental San Juan de Dios. To this end, we used a structured interview and questionnaire FES family environment of Moose, which assess interpersonal aspects of development and basic structure. According to results, 100% agree that the family is the main factor for professional help, and as for the subscales were more representative levels: conflict (61.1), moral-religious (55.5) and control (52.1).

Research of ultra-structural pathological changes of nervous, endocrine and immune system in heroin addicts / 法医学杂志

OBJECTIVE@#To investigate ultrastructural pathological changes of Heroin-Addicts.@*METHODS@#Heroin-Addicts' central nervous system, endocrine system, immune system and reproductive system in 4 cases are observed by using transmission electron microscope(TEM).@*RESULTS@#The changes of central nervous system are mitochondrion swelling, crista fragmentation and disappear. Endoplasmic reticulum dilation, nervous fibres and cell organelles reduction; mitochondrion swelling, Partial crista fragmentation and endoplasmic reticulum dilation are also found in endocrine system; Lymphocytes reduction, cytoplasm ingredient reduction and dead lymphocytes increase in immune system; in reproductive system, spermatogenic cells and cell organelles are reduced in the male and follicle disappeared in the female.@*CONCLUSION@#Ultra-structural pathological changes of heroin-addicts are presented acute, chronic oxygen deficiency degeneration and necrosis.

respiratory nasal mucosa in addicts sniffing heroin: a histological and ultrastructural study

This study was carried out on ten male addicts admitted in the Psychiatry Department of the Hadara University Hospital aged from 30- 50 years and they were sniffing heroin for more than five years, control nasal biopsies were taken from ten volunteers with matched age, and sex. The nasal biopsies were subjected to histological study using H and E stain and ultrastructural study using the transmission electron microscope. Statistical analysis of the morphological grading of the nasal mucosa was done using the t- test and the coefficient correlation test. Histologically, most of the cases of heroin sniffing addiction showed squamous metaplasia with budding of the epithelium into the lamina propria. Variable degrees of degeneration of the epithelial cells and decrease in the total number of the tunical glands with predominance of the mucous acini. Statistically, a highly significant difference was found between the addicts and the control group. Ultrastructurally, the metaplastic epithelial cells were greatly separated from each other. The mucous glands were hyperactive producing different ultrastructural types of mucous granules. The blood vessels showed hypertrophy of their endothelial cells and the lamina propria showed cellular infiltration by fibroblasts, macrophages and foreign body giant cells