ultrastructure of the foregut and its influence on bancroftian microfilariae ingestion in three Egyptian mosquito species

Laboratory observation on the uptake of bancroftian microfilaria [mf.] by 3 Egyptian mosquito species revealed that microfilaria ingested by some tested species were badly damaged during ingestion. The foregut structures in Culex pipiens, Aedes caspius and Anopheles multicolor were investigated by light and scanning microscope techniques. In Ae. caspius, which has well developed pharyngeal armatures, and An. multicolor, which has well developed cibarial armature, high proportion of microfilaria was scored and damaged. Vice versa, Cx. pipiens, considered as the main vector of bancroftian filariasis, had neither developed pharyngeal nor cibarial pumps, the percentage of damaged mf was very small. The relationship between the injury of mf in mosquito midgut and the presence of the foregut armatures was discussed

Description of hastospiculum bipinnatum [Linstow 1899] Chandler, 1929 [nematoda: diplotriaenoidea] from Egyptian varanus griseus

Hastospiculum bipinnatum worms were recovered from the thoracic cavity of the lizard Varanus griseus from Egypt. Both adult worms and their larvae were described and compared with the related species. The present is the first record of the parasite from Egypt

Physiologic surgery for lower limbs filarial lymphoedema

This study is an expansion of previously undertaken early surgical trials to test the efficacy of lymphnodovenous shunts [LNVS] for the treatment of filarial lymphoedema of the lower limbs. LNVS was carried out in fifteen patients suffering from lower limbs filarial lymphoedema over a 3.5 years period, after failed previous conservative therapy. Mean follow-up was 13.7 months. Eleven patients had benefit from this type of physiologic surgery as judged by regular postoperative limb circumference measurements, radio- isotope lymphoscanning and incidence of recurrent cellulitis or lymphangitis. The lymphnodovenous shunt [LNVS] represents an appealing therapeutic option in properly selected cases of [secondary] filarial lymphoedema of lower limbs. Larger series and longer follow- up are awaited to further confirm the durable efficacy of such procedure in a most challenging problem in vascular surgery

Primer caso de Microfilariasis de ocurrencia fatal en Santa Cruz-Bolivia / The first of case microfilariasis probably fatal in Santa Cruz-Bolivia

Se presenta el primer caso de Microfilariasis patogena probable Mansonella Ozzardi, diagnosticado por estudio Histopalogico, en un nino de 12 anos de edad, procedente de la ciudad de Santa Cruz, con un cuadro clinico atipico y desenlace fatal

Mansonella ozzardi, Faust 1929: paciente infestado con madera procedente del norte argentino / Mansonella ozzardi, Faust 1929: patient infected with wood from of the North of Argentine

Human parasitism with Filaria, Mansponella ozzardi, Faust 1929, is very frecuent in the Argentine North-West, principally in Tucumán, Catamarca and Salta provinces, But few with infestación show evidents signs. The case reported here, with conjuntival edema and rubicundity, adquired these infectation handling sawmill woods, in summer, brogth from the North-West of our place (General Alvear - Mendoza, Argentine), aproximately 1,000 Kilometers away. Probably this patients fell ill from mosquito or gnat (jejenes here) already infested, carried in the load. Diagnostic was made with sternal punture (see photography) and was treated with a veterinary product with "Invermectin". One year later, he is healthy and the blood smear is normal, without eosinophilia or parasitism

Brugia timori: experimental infection in some laboratory animals.

Experimental infection with Brugia timori of 7 jirds (Merionesunguiculatus), 4 cats and 2 monkeys (Macaca fascicularis) is described. Although no microfilariae were detected by examining 20 microliter samples of tail blood of jirds, adult worms were recovered from 6 of the 7 jirds at autopsy 69-141 days following infection. Some worms were gravid and microfilariae were found in visceral blood of 2 animals. The adult recovery rate in jirds was 16%; the male to female ratio was 1:3. In cats patent infection developed in 95-105 days but microfilaraemias were of low level and transient. No parasites were recovered from monkeys.

Experimental Brugia malayi infections in the rhesus monkey.

Twenty-eight rhesus monkeys in 3 groups were exposed to single (Group I), double (Group II), and multiple (Group III) inoculations with B. malayi infective larvae. Infections were monitored by microfilarial and blood counts, selected biochemical tests, IFA responses, and records of body temperature and lymphadenopathy before and/or after treatment with DEC. As a whole, the highest microfilaraemia levels were observed in Group II and lowest in Group III monkeys. Eosinophilia was a common occurrence but reached the highest mean levels in Group III. Intermittent fevers and lymph node enlargements were observed in all groups of monkeys and the occurrence of these appeared to be correlated. No definite pattern of antibody production was discernable among groups, but an inverse relationship existed between microfilaraemia and detectable microfilarial antibodies. Treatment with DEC produced a microfilaraemia-taxic effect within the initial half hour and responses to treatment varied according to individuals. Although post-treatment reinfection appeared to cause lymphoid responses and tissue eosinophilia, no substantial resistance to reinfection was observed.