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Rev. méd. Chile ; 147(5): 568-573, mayo 2019. tab, graf
Article Dans Espagnol | LILACS | ID: biblio-1014265

Résumé

Background: In patients with hemophilia, radionuclide synoviorthesis, or the intra-articular injection of a radionuclide to decrease the synovial hypertrophy tissue, aims to decrease or avoid hemarthrosis. Aim: To evaluate the effectiveness of radionuclide synoviorthesis in hemophilia. Material and Methods: Observational retrospective study of the evolution of 107 male patients aged 3 to 54 years who were subjected to radionuclide synoviorthesis between 2007 and 2015. Results: Of 164 treated joints, in 65% treatment was successful, (defined as zero to two hemarthroses and absence of synovitis during the follow up period), in 17% it was partially successful (defined as two or less hemarthroses, but persistence of the synovitis) and failed in 18% of the procedures. No important complications were recorded. Conclusions: Radionuclide synoviorthesis has an overall 82% success rate, is minimally invasive, can be used at any age and is inexpensive We recommend its implementation in Chilean hemophilia treatment centers.


Sujets)
Humains , Mâle , Enfant d'âge préscolaire , Enfant , Adolescent , Adulte , Adulte d'âge moyen , Jeune adulte , Radio-isotopes/administration et posologie , Rhénium/usage thérapeutique , Synovite/thérapie , Radio-isotopes de l'yttrium/usage thérapeutique , Hémarthrose/thérapie , Hémophilie A/thérapie , Synovite/physiopathologie , Synovite/imagerie diagnostique , Facteurs temps , Reproductibilité des résultats , Études rétrospectives , Résultat thérapeutique , Hémarthrose/physiopathologie , Hémarthrose/imagerie diagnostique , Hémophilie A/physiopathologie , Injections articulaires
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